Bronnendatabase

Twitter/X — Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you

Tweet/X post: Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you start prescribing them to nearly 40 million Americans, you have to expect complications and side effects, like with any medication. About 4% of people experience serious gastr - x.com Published: Tue, 03 Feb 2026 08:00:00 GMT Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you start prescribing them to nearly 40 million Americans, you have to expect complications and side

EMA/EudraVigilance — EU safety committee says semaglutide carries 'very rare' risk of vision loss - F

EU safety committee says semaglutide carries 'very rare' risk of vision loss - FirstWord Pharma Source: FirstWord Pharma Published: Fri, 06 Jun 2025 07:00:00 GMT EU safety committee says semaglutide carries 'very rare' risk of vision loss  FirstWord Pharma

Cochrane/Nature — A systematic review and meta-analysis of the efficacy and safety of pharmacologi

A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults - Nature Source: Nature Published: Thu, 02 Oct 2025 07:00:00 GMT A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults  Nature

TCTMD.com — Weight Regained Within 18 Months of Stopping GLP-1 Drugs - TCTMD.com

Weight Regained Within 18 Months of Stopping GLP-1 Drugs - TCTMD.com Source: TCTMD.com Published: Thu, 08 Jan 2026 08:00:00 GMT Weight Regained Within 18 Months of Stopping GLP-1 Drugs  TCTMD.com

Reddit r/compoundedtirzepatide — Injection Site Redness Doesn’t Go Away

Does anyone have the same? Been using Reta since November 2025 and last 10 injections are red. I use sterile everything, made sure to do so. Actually it was 2 before visible and now I see all 10 they seem to appear more red in the past couple weeks. Wondering if any advice how to get rid of them.

Reddit r/compoundedtirzepatide — If Saxenda/Liraglutide has been feeling less effective, make sure you're rotatin

The past few months I've been disheartened by a progressive reduction in efficacy from Saxenda. Some food noise began coming back, and the appetite reduction has felt lessened. It turns out, I may have been causing this issue myself. I've been injecting Saxenda into the same spot every day for months, oblivious to the fact that you're supposed to rotate injection sites. When I touch that area of my stomach, I can feel a slightly hard little lump, but I didn't think very much of it until I read

Reddit r/compoundedtirzepatide — If Saxenda/Liraglutide has been feeling less effective, make sure you're rotatin

The past few months I've been disheartened by a progressive reduction in efficacy from Saxenda. Some food noise began coming back, and the appetite reduction has felt lessened. It turns out, I may have been causing this issue myself. I've been injecting Saxenda into the same spot every day for months, oblivious to the fact that you're supposed to rotate injection sites. When I touch that area of my stomach, I can feel a slightly hard little lump, but I didn't think very much of it until I read

Reddit r/compoundedtirzepatide — Blood Test for Peptide Stack

37, 193, 5'-10" male, on a pretty popular peptide stack consisting of Retatrutide (2 months in at 4mg), Tessamorelin (3 weeks in), Ipamorelin, GLOW. Did Mots-c for 1 month at 5mg a day 6 days a week, but stopped due to injection site lumps and itching. About to also add Pinealon and Epithalon for 20 and 10 days respectively. I did get these all tested for Endotoxin, Sterility and heavy metals in addition to mass analysis. Probably not wise to inject peps... but if im gonna do this, I'd like to d

Reddit r/PeptideSource — Workout Suggestions

Hi everyone! I wanted to ask what your workout routines are? I have crazy fatigue and going to the gym can be quite difficult. If I go three times in one week, I usually end up needing the entire next week to recover because I’ve completely drained my energy so I wanted to ask if you guys have any suggestions for working out while having endo.

Reddit r/semaglutide — Workout Suggestions

Hi everyone! I wanted to ask what your workout routines are? I have crazy fatigue and going to the gym can be quite difficult. If I go three times in one week, I usually end up needing the entire next week to recover because I’ve completely drained my energy so I wanted to ask if you guys have any suggestions for working out while having endo.

Twitter/X — I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effe

Tweet/X post: I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effect I'd never heard of... and doctors say it's now on the rise - x.com Published: Mon, 25 Aug 2025 07:00:00 GMT I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effect I'd never heard of... and doctors say it's now on the rise  x.com

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I have taken Bydureon for about 3 months. My blood sugar has gone from over 200 to 125-180, which is a nice improvement. I do not yet know what has happened to my A1c. I inject the Bydureon into my thigh. I alternate sides each week so each thigh has two weeks to recover. I have had no side effects. I have been trying to lose weight in 2014. So far, I am down 14 pounds from 179 to 165 pounds."

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

India News — India’s doctors sound alarm over boom in availability of weight loss jabs - The

India’s doctors sound alarm over boom in availability of weight loss jabs - The Guardian Published: Sun, 21 Dec 2025 08:00:00 GMT India’s doctors sound alarm over boom in availability of weight loss jabs  The Guardian

Reddit r/Ozempic — Pancreatitis

I got hospitalized for acute pancreatitis at 23 last year for 6 days and later relapsed a month later and until I went back again for only 4 days in February but the pain wasn't as bad. I started binge drinking again and was on a bender this past weekend while at an event in my city and vented/crying to my mom about personal issues and I shared embarrassing texts to my sister (it wasn't really embarrassing in hindsight it was just me showing her my art and my favorite songs and we talked for hou

Reddit r/Ozempic — Pancreatitis

I got hospitalized for acute pancreatitis at 23 last year for 6 days and later relapsed a month later and until I went back again for only 4 days in February but the pain wasn't as bad. I started binge drinking again and was on a bender this past weekend while at an event in my city and vented/crying to my mom about personal issues and I shared embarrassing texts to my sister (it wasn't really embarrassing in hindsight it was just me showing her my art and my favorite songs and we talked for hou

Reddit r/Ozempic — Emergency room/hospital for trans person

​ So I'm needing to go to the hospital/emergency room. I think I have pancreatitis. I have blue cross blue shield. I'm a trans woman. What hospital has good lgbt care. Had a really bad experience with Kaiser last year where I was treated horribly and put in an unsafe situation by staff. I have new insurance now. I'm nervous and scared to go to a hospital again but need help. Any recommendations on which to go to as a trans person? Will probably go to the ER tomorrow when my partner

Reddit r/Mounjaro — Sudden shift to happiness (does mention talk of suicide.)

I am now happy I guess, which is pretty awesome cause being happy, smiling, randomly is nice, cause like a month\~ ago I absolutely spiraled, and was realistically, not gonna last long, and right as I got absolutely ***miserable*** (prolly would’ve killed myself the next day or the next few.) in the next day, feeling ok-ish early in the day, got really, REALLY *happy* later in the day, where I literally described it as drugged and couldn’t stop talking about it, and ever since then I’ve felt mi

Reddit r/intermittentfasting — Emergency room/hospital for trans person

​ So I'm needing to go to the hospital/emergency room. I think I have pancreatitis. I have blue cross blue shield. I'm a trans woman. What hospital has good lgbt care. Had a really bad experience with Kaiser last year where I was treated horribly and put in an unsafe situation by staff. I have new insurance now. I'm nervous and scared to go to a hospital again but need help. Any recommendations on which to go to as a trans person? Will probably go to the ER tomorrow when my partner

PubMed — Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis.

N Engl J Med. 2024 Oct 31;391(17):1573-1583. doi: 10.1056/NEJMoa2403664. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis. Bliddal H(1), Bays H(1), Czernichow S(1), Uddén Hemmingsson J(1), Hjelmesæth J(1), Hoffmann Morville T(1), Koroleva A(1), Skov Neergaard J(1), Vélez Sánchez P(1), Wharton S(1), Wizert A(1), Kristensen LE(1); STEP 9 Study Group. Collaborators: Akhras R, Dzongowski P, Lowe D, Tytus R, Wharton S, Londoño Patiño J, Jaller Raad J, Vélez Sánchez P, Hau

Twitter/X — Some patients have reported a negative experience on GLP-1s -- a sort of emotion

Tweet/X post: Some patients have reported a negative experience on GLP-1s -- a sort of emotional flattening colloquially referred to as "Ozempic personality." Read more at: - x.com Published: Sun, 26 Apr 2026 17:06:00 GMT Some patients have reported a negative experience on GLP-1s -- a sort of emotional flattening colloquially referred to as "Ozempic personality." Read more at:  x.com

Reddit r/compoundedtirzepatide — Accidentally tasted t and it was awful

i do subq injections and on my last injection it bled a little more than normal, drop of blood came from the injection site and on instinct i wiped it on my finger & put it in my mouth. it was so bad. It tasted like what i imagine the bottom of a shoe tastes like after going on a long hike and stepping in dog shit. Like how dirt tastes if the dirt was evil and something died in it. Do not put t in your mouth under any conditions. thought you guys might want to hear lol

Reddit r/WegovyWeightLoss — Accidentally tasted t and it was awful

i do subq injections and on my last injection it bled a little more than normal, drop of blood came from the injection site and on instinct i wiped it on my finger & put it in my mouth. it was so bad. It tasted like what i imagine the bottom of a shoe tastes like after going on a long hike and stepping in dog shit. Like how dirt tastes if the dirt was evil and something died in it. Do not put t in your mouth under any conditions. thought you guys might want to hear lol

Quora — I am diabetic 8/10. What medicine should I take now? - Quora

Quora Q&A: I am diabetic 8/10. What medicine should I take now? - Quora Published: Thu, 17 Apr 2025 07:00:00 GMT I am diabetic 8/10. What medicine should I take now?  Quora

Science Daily — Simple “gut reset” may stop weight gain after Ozempic or Wegovy - Science Daily

Simple “gut reset” may stop weight gain after Ozempic or Wegovy - Science Daily Source: Science Daily Published: Thu, 23 Apr 2026 06:46:53 GMT Simple “gut reset” may stop weight gain after Ozempic or Wegovy  Science Daily

The 19th News — Sleepless nights, diapers and GLP-1s: More people are turning to weight loss dru

Sleepless nights, diapers and GLP-1s: More people are turning to weight loss drugs after having babies - The 19th News Source: The 19th News Published: Thu, 23 Apr 2026 13:12:04 GMT Sleepless nights, diapers and GLP-1s: More people are turning to weight loss drugs after having babies  The 19th News

Reddit r/compoundedtirzepatide — Sleeping 11 hours a day and still tired

(24F) The past few months, I’ve been hit with this extreme, debilitating fatigue making it hard to do anything. Even after getting 10-11 hours of sleep everyday, I feel tired. Also, recently, I’ve been getting full really easily (after just a couple bites of food). I still try to eat a normal amount so that I get enough calories and nutrients. The fatigue came first so I don’t think this is the cause of the fatigue. I used to be a fairly active, high-energy person, so this has been especially de

Reddit r/compoundedtirzepatide — Sleeping 11 hours a day and still tired

(24F) The past few months, I’ve been hit with this extreme, debilitating fatigue making it hard to do anything. Even after getting 10-11 hours of sleep everyday, I feel tired. Also, recently, I’ve been getting full really easily (after just a couple bites of food). I still try to eat a normal amount so that I get enough calories and nutrients. The fatigue came first so I don’t think this is the cause of the fatigue. I used to be a fairly active, high-energy person, so this has been especially de

Reddit r/compoundedtirzepatide — Is this RLS or something else?

I had covid in december and i am now still in recovery from post covid syndrome. I suffer from headaches, breathing problems and fatigue. But the worst part is i cannot fall asleep. I have sleeping meds and melatonin but as soon as i go to bet my body decides i need to go and walk. My legs feel normal but i have this weird muscle tension and tingling in my lower belly that is sooo awful that it makes me wanna scream. It only stops when i walk. I have occasionally had this ever since i was a ch

Reddit r/compoundedtirzepatide — Is this RLS or something else?

I had covid in december and i am now still in recovery from post covid syndrome. I suffer from headaches, breathing problems and fatigue. But the worst part is i cannot fall asleep. I have sleeping meds and melatonin but as soon as i go to bet my body decides i need to go and walk. My legs feel normal but i have this weird muscle tension and tingling in my lower belly that is sooo awful that it makes me wanna scream. It only stops when i walk. I have occasionally had this ever since i was a ch

Reddit r/Mounjaro — I think its just depression + self hatred but just wanting to know if others fee

Recently ive not understood human feelings or processes, it’s not like I never felt them I just don’t understand them in an odd way. I feel hunger, I understand that I must eat to gain energy to survive yet I dislike that I must and I have to I dont understand why but all the same feel and know why, yet I also feel great pleasure for consuming food and quite enjoy so, yet I don’t like that I consume I quite wish I could just not. As for emotions, for example anxiety confuses me, my mind and body

PubMed — Alopecia and Semaglutide: Connecting the Dots for Patient Safety.

J Cosmet Dermatol. 2025 Mar;24(3):e70125. doi: 10.1111/jocd.70125. Alopecia and Semaglutide: Connecting the Dots for Patient Safety. Haykal D(1). Author information: (1)Centre Laser Palaiseau, private practice, Palaiseau, France. DOI: 10.1111/jocd.70125 PMCID: PMC11909624 PMID: 40087997 Conflict of interest statement: The author declares no conflicts of interest.

PubMed — 10.1111/jdv.20197. Epub 2024 Jun 24.

J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e153-e154. doi: 10.1111/jdv.20197. Epub 2024 Jun 24. Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023. Godfrey H(1), Leibovit-Reiben Z(1), Jedlowski P(2), Thiede R(2). Author information: (1)University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA. (2)Division of Dermatology, University of Arizona College of Medicine

PubMed — 10.1111/jdv.20197. Epub 2024 Jun 24.

J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e153-e154. doi: 10.1111/jdv.20197. Epub 2024 Jun 24. Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023. Godfrey H(1), Leibovit-Reiben Z(1), Jedlowski P(2), Thiede R(2). Author information: (1)University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA. (2)Division of Dermatology, University of Arizona College of Medicine

PubMed — Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use:

Cureus. 2025 Sep 16;17(9):e92454. doi: 10.7759/cureus.92454. eCollection 2025 Sep. Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review. Alsuwailem OA(1), Alanazi R(2), Almutairi HM(3), Asiree RH(3), Almutairi W(4), Almutairi TM(3), Zamandar A(4), Alkhames S(5). Author information: (1)College of Medicine and Surgery, King Faisal University, Al-Ahsa, SAU. (2)College of Medicine, Dar Al Uloom University, Riyadh, SAU. (3)College of Medicine, Majm

Twitter/X — A large study of 23andMe customers found variants in two genes that play a role

Tweet/X post: A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting. - x.com Published: Fri, 17 Apr 2026 17:25:14 GMT A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting.  x.com

Twitter/X — A large study of 23andMe customers found variants in two genes that play a role

Tweet/X post: A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting. - x.com Published: Fri, 17 Apr 2026 17:25:14 GMT A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting.  x.com

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Sun, 19 Apr 2026 23:00:13 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

EMA/EudraVigilance — European drugs regulator to review Wegovy, Ozempic following reports of suicidal

European drugs regulator to review Wegovy, Ozempic following reports of suicidal thoughts - CNBC Source: CNBC Published: Mon, 10 Jul 2023 07:00:00 GMT European drugs regulator to review Wegovy, Ozempic following reports of suicidal thoughts  CNBC

Docwire News — Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawa

Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawal - Docwire News Source: Docwire News Published: Fri, 24 Apr 2026 18:27:07 GMT Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawal  Docwire News

Wiley — Semaglutide impacts skeletal muscle to a similar extent as caloric restriction i

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet-induced obesity - Wiley Source: Wiley Published: Mon, 22 Sep 2025 07:00:00 GMT Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet-induced obesity  Wiley

UNC Health — New Study Finds Weight Loss Causes Significant Muscle Loss - UNC Health

New Study Finds Weight Loss Causes Significant Muscle Loss - UNC Health Source: UNC Health Published: Fri, 17 Apr 2026 16:01:26 GMT New Study Finds Weight Loss Causes Significant Muscle Loss  UNC Health

MedPage Today — 'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s? -

'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s? - MedPage Today Source: MedPage Today Published: Thu, 23 Apr 2026 21:43:48 GMT 'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s?  MedPage Today

FDA FAERS — exenatide — WEIGHT DECREASED

FDA adverse event reports for exenatide: WEIGHT DECREASED reported 12125 times out of 94694 total reports (12.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Reddit r/loseit — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Reddit r/loseit — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Reddit r/Zepbound — Suffering from past few years from Cognitive Function which destroyed my life

Hi guys, I suffer from brutal 6-7 year old maladaptive daydreaming habit, overthinking, And 2024 at end year I went to pschiatrist and they gave me SSRIs and now I also suffer from PSSD, anhedonia, and emotional blunting. On top of it all these, I suffer from serious brain fog, short term and long term memory issues, can't execute any task or finish any task, numb brain, no creativity, not able to think at all, and my brain cant process any information and every small task looks very big to me.

Reddit r/Ozempic — 28M discomfort just under ribs on right side

Needless to say throwaway account. Some prior history. (28M) Gall bladder removal about a year ago Kidney stones every few years High bp (managed with losartan) Gerd (managed with omeprasole) And it has been noted on CT scans that I have fatty liver. (Trying to eat better and taking fish oil supplements to hope they help, lol) I weigh about 250 (working on losing weight, dropped about 8ish pounds in the last 2 months) 6ft Prior vitamin d deficiency (i take supplements for now) The

Reddit r/Ozempic — 28M discomfort just under ribs on right side

Needless to say throwaway account. Some prior history. (28M) Gall bladder removal about a year ago Kidney stones every few years High bp (managed with losartan) Gerd (managed with omeprasole) And it has been noted on CT scans that I have fatty liver. (Trying to eat better and taking fish oil supplements to hope they help, lol) I weigh about 250 (working on losing weight, dropped about 8ish pounds in the last 2 months) 6ft Prior vitamin d deficiency (i take supplements for now) The

Reddit r/Ozempic — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Reddit r/Ozempic — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Reddit r/Ozempic — Unable to sleep due to reflux

21 F, 189 lbs, 5’2”, never smoked. I’m autistic(level 1) with severe ADHD and OCD, so I’m not very independent(live at home and still need mom’s permission for everything- I’m very smart and mentally competent but too scatterbrained to take care of myself because I just don’t remember to) and cannot drive. I take a LOT of meds but haven’t taken most of them in 24 hours, only Nexium(40mg a few hours ago), Pepcid(40mg recently), Zofran(I can’t remember the dosage but it’s just 1 little pill, a f

Reddit r/Ozempic — acid reflux and working night shifts

Hi, I've been mostly lurking on this subreddit reading about everyones experience with GERD/LPR. I've been recently diagnosed and I'm trying to guide myself throught it - first with diet and taking care of myself properly. Decided to go on proper diet and I wanna try my best to stick to it, but there's a little problem - my work schedule. I work 2 night shifts, then I have 2 days off and then i work normal shifts that are up to 12 hours. How do i manage with my diet during the night? Does anyo

Reddit r/Mounjaro — Suffering from past few years from Cognitive Function which destroyed my life

Hi guys, I suffer from brutal 6-7 year old maladaptive daydreaming habit, overthinking, And 2024 at end year I went to pschiatrist and they gave me SSRIs and now I also suffer from PSSD, anhedonia, and emotional blunting. On top of it all these, I suffer from serious brain fog, short term and long term memory issues, can't execute any task or finish any task, numb brain, no creativity, not able to think at all, and my brain cant process any information and every small task looks very big to me.

Reddit r/Mounjaro — HELP. Went from months of emotional blunting to overwhelming emotion in a split

I’ve been on escitalopram since October, started out at 5mg and have been on 20mg since late November-early December. I’m generally doing a lot better than I was before, probably due to the emotional blunting, which I prefer to the multiple daily panic attacks and constant thoughts of ending things. The thing is I got some upsetting news at work yesterday and since then I feel completely overwhelmed with anger and sadness and can’t stop crying, which I hadn’t been able to do for months. Litera

PubMed — Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss

JAMA. 2021 Apr 13;325(14):1414-1425. doi: 10.1001/jama.2021.3224. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. Rubino D(1), Abrahamsson N(2), Davies M(3)(4), Hesse D(5), Greenway FL(6), Jensen C(5), Lingvay I(7), Mosenzon O(8), Rosenstock J(9), Rubio MA(10), Rudofsky G(11), Tadayon S(5), Wadden TA(12), Dicker D(13); STEP 4 Investigators. Collaborators: Friberg M, Sjödin

MHRA/The Pharmaceutical Journal — ‘Life-threatening condition’ added to Mounjaro patient information leaflet - The

‘Life-threatening condition’ added to Mounjaro patient information leaflet - The Pharmaceutical Journal Source: The Pharmaceutical Journal Published: Fri, 28 Nov 2025 08:00:00 GMT ‘Life-threatening condition’ added to Mounjaro patient information leaflet  The Pharmaceutical Journal

India News — India's 'Mounjaro brides': weight-loss injections become part of pre-wedding pre

India's 'Mounjaro brides': weight-loss injections become part of pre-wedding preparation - Reuters Published: Sat, 04 Apr 2026 07:00:00 GMT India's 'Mounjaro brides': weight-loss injections become part of pre-wedding preparation  Reuters

Reddit r/PeptideSource — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/PeptideSource — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/semaglutide — Reversal expectations

I had a perforated bowel due to SEVERE constipation six months ago. I woke up from surgery with a colostomy bag. Since then the whole goal of my recovery has been to have it reversed. I don't mean to offend anyone here, it just is what it is. My reversal is scheduled for May 1. Colonoscopy the day before. The surgery will be open because I have massive scarring; my incision was left open with a wound vac because it was such a mess in there. So the surgeon will go in through the same incision an

Reddit r/semaglutide — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/semaglutide — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/semaglutide — Benefiber vs Metamucil

The doctor told me to take Senokot for constipation since at 6 weeks I’m still having trouble. It worked but caused me to rush to the bathroom and have messy poop. MiraLAX and even the MiraFast did that too. The nurse said she takes Metamusil but I chose to buy a store brand of Benifiber since it’s not gritty and mixes with anything. Though I have gluten issues and it says its gluten free by the way the make it, I’m afraid to take it. Is there anything that works and doesn’t cause diarrhea or ru

Reddit r/semaglutide — Benefiber vs Metamucil

The doctor told me to take Senokot for constipation since at 6 weeks I’m still having trouble. It worked but caused me to rush to the bathroom and have messy poop. MiraLAX and even the MiraFast did that too. The nurse said she takes Metamusil but I chose to buy a store brand of Benifiber since it’s not gritty and mixes with anything. Though I have gluten issues and it says its gluten free by the way the make it, I’m afraid to take it. Is there anything that works and doesn’t cause diarrhea or ru

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Reddit r/loseit — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/loseit — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Reddit r/Zepbound — Just had surgery, any tips?

I just got home from the hospital today from gallbladder surgery and emergency escaped gallstone surgery (I had a 3cm gallstone ripping apart my pancreas), my mom and grandma watched him while I was in the hospital. He is a super clingy baby because he's been teething. He weighs about 20lbs and has been killing my abdomen. Does anyone have any tips on how to lift and take care of him and how to not suffer so much from the mom guilt of occasionally having to let him just cry for a second to regai

Reddit r/Zepbound — Just had surgery, any tips?

I just got home from the hospital today from gallbladder surgery and emergency escaped gallstone surgery (I had a 3cm gallstone ripping apart my pancreas), my mom and grandma watched him while I was in the hospital. He is a super clingy baby because he's been teething. He weighs about 20lbs and has been killing my abdomen. Does anyone have any tips on how to lift and take care of him and how to not suffer so much from the mom guilt of occasionally having to let him just cry for a second to regai

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Sun, 19 Apr 2026 23:00:13 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

WHO/Nature — Pharmacovigilance analysis of neurological adverse events associated with GLP-1

Pharmacovigilance analysis of neurological adverse events associated with GLP-1 receptor agonists based on the FDA Adverse Event Reporting System - Nature Source: Nature Published: Sat, 24 May 2025 07:00:00 GMT Pharmacovigilance analysis of neurological adverse events associated with GLP-1 receptor agonists based on the FDA Adverse Event Reporting System  Nature

India News — Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Los

Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Loss With Mounjaro - Outlook Luxe Published: Sat, 18 Apr 2026 07:30:00 GMT Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Loss With Mounjaro  Outlook Luxe

Ars Technica — There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests - A

There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests - Ars Technica Source: Ars Technica Published: Tue, 25 Nov 2025 08:00:00 GMT There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests  Ars Technica

McGill University — Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound - McGill Universit

Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound - McGill University Source: McGill University Published: Fri, 01 Aug 2025 07:00:00 GMT Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound  McGill University

MedPage Today — GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedP

GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedPage Today Source: MedPage Today Published: Tue, 21 Apr 2026 19:36:03 GMT GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk  MedPage Today

MedPage Today — GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedP

GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedPage Today Source: MedPage Today Published: Tue, 21 Apr 2026 19:36:03 GMT GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk  MedPage Today

Medical Xpress — Weight loss leads to notable muscle loss, study finds - Medical Xpress

Weight loss leads to notable muscle loss, study finds - Medical Xpress Source: Medical Xpress Published: Fri, 17 Apr 2026 18:40:04 GMT Weight loss leads to notable muscle loss, study finds  Medical Xpress

EMJ — Tirzepatide linked to more lean mass loss than semaglutide - EMJ

Tirzepatide linked to more lean mass loss than semaglutide - EMJ Source: EMJ Published: Fri, 17 Apr 2026 11:17:54 GMT Tirzepatide linked to more lean mass loss than semaglutide  EMJ

EMJ — Tirzepatide linked to more lean mass loss than semaglutide - EMJ

Tirzepatide linked to more lean mass loss than semaglutide - EMJ Source: EMJ Published: Fri, 17 Apr 2026 11:17:54 GMT Tirzepatide linked to more lean mass loss than semaglutide  EMJ

Reddit r/diabetes_t2 — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Reddit r/diabetes_t2 — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

Reddit r/diabetes — Nothing i do helps

Tldr nothing I've tried helps with my scalp and I'm really struggling with hair loss and breakage I've had eczema, mild and mostly managed without meds for most of my life. Then a couple years ago my skin and scalp flipped out. Weeping broken skin at the groin, behind the ears and my scalp was inflamed, red painful and itchy. Got to a Dermatologist, trying different tropicals, even tried biologics (a couple because at first they thought it was psoriasis) nothing really made a big difference.

Reddit r/PCOS — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Reddit r/PCOS — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

Reddit r/compoundedtirzepatide — Nothing i do helps

Tldr nothing I've tried helps with my scalp and I'm really struggling with hair loss and breakage I've had eczema, mild and mostly managed without meds for most of my life. Then a couple years ago my skin and scalp flipped out. Weeping broken skin at the groin, behind the ears and my scalp was inflamed, red painful and itchy. Got to a Dermatologist, trying different tropicals, even tried biologics (a couple because at first they thought it was psoriasis) nothing really made a big difference.

Reddit r/PeptideSource — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Reddit r/PeptideSource — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

medRxiv — GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic

Preprint: GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic review and meta-analysis Authors: Hume, S.; Bakker, L.; Caganek, T.; Rooprai, A. Date: 2026-03-23 Category: endocrinology Abstract: BackgroundThere are concerns that glucagon-like peptide-1 receptor agonists (GLP1s) increase the risk of acute pancreatitis. MethodsWe searched Medline and clinicaltrials.gov in March 2026 for placebo-controlled randomized trials of semaglutide and tirzepatide reporting the i

medRxiv — GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic

Preprint: GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic review and meta-analysis Authors: Hume, S.; Bakker, L.; Caganek, T.; Rooprai, A. Date: 2026-03-23 Category: endocrinology Abstract: BackgroundThere are concerns that glucagon-like peptide-1 receptor agonists (GLP1s) increase the risk of acute pancreatitis. MethodsWe searched Medline and clinicaltrials.gov in March 2026 for placebo-controlled randomized trials of semaglutide and tirzepatide reporting the i

WHO/CBS News — FDA warns Novo Nordisk over unreported potential Ozempic side effects - CBS News

FDA warns Novo Nordisk over unreported potential Ozempic side effects - CBS News Source: CBS News Published: Tue, 10 Mar 2026 07:00:00 GMT FDA warns Novo Nordisk over unreported potential Ozempic side effects  CBS News

India News — Centre increases monitoring of weight-loss drugs, flags safety concerns - Busine

Centre increases monitoring of weight-loss drugs, flags safety concerns - Business Standard Published: Sat, 04 Apr 2026 07:00:00 GMT Centre increases monitoring of weight-loss drugs, flags safety concerns  Business Standard

India News — Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss dr

Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss drugs - The News Mill Published: Mon, 20 Apr 2026 11:43:47 GMT Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss drugs  The News Mill

Reddit r/diabetes — How far should I push myself.

This is more of a cardio question than specifically a running question but thought it would be a good place to ask. How do I know when to stop running? I'm an intermediate weight lifter that started hitting cardio related walls like consitent nausea. What is the ideal way to push your cardio I assume throwing up every time is not ideal. Do i just stop when it feels like a heart attack, tight chest can barely breathe or should I stop even earlier.

Reddit r/diabetes — How far should I push myself.

This is more of a cardio question than specifically a running question but thought it would be a good place to ask. How do I know when to stop running? I'm an intermediate weight lifter that started hitting cardio related walls like consitent nausea. What is the ideal way to push your cardio I assume throwing up every time is not ideal. Do i just stop when it feels like a heart attack, tight chest can barely breathe or should I stop even earlier.

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Cochrane/Cochrane Library — Semaglutide for adults living with obesity - Bracchiglione, J - 2025 - Cochrane

Semaglutide for adults living with obesity - Bracchiglione, J - 2025 - Cochrane Library Source: Cochrane Library Published: Thu, 30 Oct 2025 07:00:00 GMT Semaglutide for adults living with obesity - Bracchiglione, J - 2025  Cochrane Library

Reddit r/loseit — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Reddit r/loseit — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Reddit r/loseit — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Reddit r/Ozempic — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Reddit r/Ozempic — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Reddit r/Ozempic — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Reddit r/intermittentfasting — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Wed, 15 Apr 2026 23:00:18 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

EMA/EudraVigilance — Weight-loss jabs investigated for suicide risk - BBC

Weight-loss jabs investigated for suicide risk - BBC Source: BBC Published: Sun, 09 Jul 2023 07:00:00 GMT Weight-loss jabs investigated for suicide risk  BBC

MHRA/genomicsengland.co.uk — The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of

The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of acute pancreatitis - genomicsengland.co.uk Source: genomicsengland.co.uk Published: Thu, 26 Jun 2025 07:00:00 GMT The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of acute pancreatitis  genomicsengland.co.uk

MHRA/The BMJ — GLP-1 drugs: New warning after rise in reported deaths from pancreatitis - The B

GLP-1 drugs: New warning after rise in reported deaths from pancreatitis - The BMJ Source: The BMJ Published: Fri, 30 Jan 2026 08:00:00 GMT GLP-1 drugs: New warning after rise in reported deaths from pancreatitis  The BMJ

Cureus — Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation

Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists and Other Anti-obesity Drugs - Cureus Source: Cureus Published: Sun, 19 Oct 2025 07:00:00 GMT Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists and Other Anti-obesity Drugs  Cureus

Scientific American — Experimental GLP-3 weight-loss drug retatrutide shows promising results in clini

Experimental GLP-3 weight-loss drug retatrutide shows promising results in clinical trial - Scientific American Source: Scientific American Published: Thu, 19 Mar 2026 07:00:00 GMT Experimental GLP-3 weight-loss drug retatrutide shows promising results in clinical trial  Scientific American

FDA FAERS — semaglutide — PRODUCT USE IN UNAPPROVED INDICATION

FDA adverse event reports for semaglutide: PRODUCT USE IN UNAPPROVED INDICATION reported 3039 times out of 99460 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Reddit r/PeptideSource — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/PeptideSource — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/PeptideSource — Am I crazy or is there something wrong with me? 20F

Hi everyone! About me: I'm a white 20 female and I'm a 192 pounds. I don't smoke, drink, and or use any drugs. The only existing medical issue that I have is diagnosed PCOS. I do have a constant history with constipation. As for medications, I'm on Concerta (36mg) for ADHD. Semaglutide injections once a week (15 units, been on it for a year and have lost over 70 pounds with no problems). Last, Zofran (8mg) as needed. I work out and eat clean as well. Family history: On my father's side; grandm

Reddit r/semaglutide — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/semaglutide — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/semaglutide — Need advice on whether this gallbladder actually needs to come out. Ultrasound p

**5’5”, 30 years old, 185 pounds, don’t smoke, 50mg vyvanse and 10mg xyzal a day. Currently use Zyns, vaped for about a year. I have PCOS, mild insulin resistance, Chronic Spontaneous Urticaria, IBS-C, and got a 5mm colon adenoma removed earlier this month.** I recently had an abdominal ultrasound that showed a gallbladder polyp, with the radiology report stating “multiple polyps, one polyp up to 6 mm.” My gallbladder wall measured 1.66 mm (normal), common bile duct about 5.8 mm (upper end of no

Reddit r/WegovyWeightLoss — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Reddit r/WegovyWeightLoss — Why are doctors so hesitant to remove gallbladders?

That’s been my observation, anyway. I know a few people, including myself, that have confirmed stones + a ton of symptoms due to it but doctors refuse to do surgery. Why is that?

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/loseit — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/loseit — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Reddit r/Zepbound — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Reddit r/Zepbound — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Reddit r/Zepbound — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Reddit r/Zepbound — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Reddit r/Zepbound — Why are doctors so hesitant to remove gallbladders?

That’s been my observation, anyway. I know a few people, including myself, that have confirmed stones + a ton of symptoms due to it but doctors refuse to do surgery. Why is that?

Reddit r/Zepbound — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/Zepbound — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/Zepbound — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Reddit r/Zepbound — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "No need for details. I experienced the same awful side effects as many of the posters. So I quit the drug and went on a low-carb diet (little or no grains, starches, or sugar) and started walking 20 minutes every day as fast as I could. Lost 40 lbs. A1C went from 8.0 to 5.5. Never felt better. But I am still diabetic, meaning I cannot go back to my old ways. If I can do it, you can do it. Oh, and the money I am saving!"

FDA FAERS — dulaglutide — EXTRA DOSE ADMINISTERED

FDA adverse event reports for dulaglutide: EXTRA DOSE ADMINISTERED reported 3106 times out of 101618 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/semaglutide — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Reddit r/semaglutide — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/WegovyWeightLoss — Restarting Zepbound after 3 weeks off, doctor said it was okay to continue on th

TW: Pregnancy Loss Hi everyone! My journey has been a bit weird so far. I started zepbound the first Friday of February. I lost about 10 pounds on the 2.5 and 8 pounds on the 5mg. I ended up ovulating and wound up pregnant with my positive happening on March 24th. I stopped my zepbound accordingly. Unfortunately, this ended in a miscarriage. I asked the NP if it was okay to continue on the 5mg and she agreed. I had missed 3 doses. I'm just wondering if anyone has had a similar experience of

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/Zepbound — Restarting Zepbound after 3 weeks off, doctor said it was okay to continue on th

TW: Pregnancy Loss Hi everyone! My journey has been a bit weird so far. I started zepbound the first Friday of February. I lost about 10 pounds on the 2.5 and 8 pounds on the 5mg. I ended up ovulating and wound up pregnant with my positive happening on March 24th. I stopped my zepbound accordingly. Unfortunately, this ended in a miscarriage. I asked the NP if it was okay to continue on the 5mg and she agreed. I had missed 3 doses. I'm just wondering if anyone has had a similar experience of

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Reddit r/Ozempic — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Reddit r/Ozempic — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

PubMed — 10.1016/S2213-8587(24)00182-7. Epub 2024 Jul 29.

Lancet Diabetes Endocrinol. 2024 Sep;12(9):631-642. doi: 10.1016/S2213-8587(24)00182-7. Epub 2024 Jul 29. Efficacy and safety of once-weekly semaglutide 2·4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial. McGowan BM(1), Bruun JM(2), Capehorn M(3), Pedersen SD(4), Pietiläinen KH(5), Muniraju HAK(6), Quiroga M(7), Varbo A(7), Lau DCW(8); STEP 10 Study Group. Author information: (1)Department of Di

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Wed, 15 Apr 2026 23:00:18 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

Twitter/X — 'I was told about the hair loss but I never expected this': The brutal Mounjaro

Tweet/X post: 'I was told about the hair loss but I never expected this': The brutal Mounjaro side-effect that only affects women - and doctors aren't warning them about it - x.com Published: Sat, 29 Nov 2025 08:00:00 GMT 'I was told about the hair loss but I never expected this': The brutal Mounjaro side-effect that only affects women - and doctors aren't warning them about it  x.com

Medical Xpress — Tirzepatide's benefits fade for most: Weight and health markers rebound after wi

Tirzepatide's benefits fade for most: Weight and health markers rebound after withdrawal, study finds - Medical Xpress Source: Medical Xpress Published: Fri, 28 Nov 2025 08:00:00 GMT Tirzepatide's benefits fade for most: Weight and health markers rebound after withdrawal, study finds  Medical Xpress

CLGF — New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How F

New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How Fast - CLGF Source: CLGF Published: Wed, 25 Feb 2026 08:00:00 GMT New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How Fast  CLGF

MedCentral — Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps - Me

Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps - MedCentral Source: MedCentral Published: Wed, 31 Dec 2025 08:00:00 GMT Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps  MedCentral

SciTechDaily — Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks

Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks, Study Warns - SciTechDaily Source: SciTechDaily Published: Mon, 12 Jan 2026 08:00:00 GMT Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks, Study Warns  SciTechDaily

The BMJ — After the Injection: GLP-1 Discontinuation and Weight Regain - The BMJ

After the Injection: GLP-1 Discontinuation and Weight Regain - The BMJ Source: The BMJ Published: Wed, 07 Jan 2026 08:00:00 GMT After the Injection: GLP-1 Discontinuation and Weight Regain  The BMJ

University of Utah Health — New Study Raises Questions About How Ozempic Affects Muscle Size and Strength -

New Study Raises Questions About How Ozempic Affects Muscle Size and Strength - University of Utah Health Source: University of Utah Health Published: Tue, 05 Aug 2025 07:00:00 GMT New Study Raises Questions About How Ozempic Affects Muscle Size and Strength  University of Utah Health

The Guardian — Is a new weight-loss drug making people fall out of love? - The Guardian

Is a new weight-loss drug making people fall out of love? - The Guardian Source: The Guardian Published: Mon, 06 Apr 2026 07:00:00 GMT Is a new weight-loss drug making people fall out of love?  The Guardian

KTLA — ‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs -

‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs - KTLA Source: KTLA Published: Thu, 16 Apr 2026 20:57:01 GMT ‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs  KTLA

The Washington Post — What is ‘Ozempic personality,’ and why does it make life feel ‘meh’? - The Washi

What is ‘Ozempic personality,’ and why does it make life feel ‘meh’? - The Washington Post Source: The Washington Post Published: Thu, 16 Apr 2026 16:00:00 GMT What is ‘Ozempic personality,’ and why does it make life feel ‘meh’?  The Washington Post

Reddit r/compoundedtirzepatide — Do you guys get these itchy spots ?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Reddit r/compoundedtirzepatide — Itchy injection sites at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Reddit r/compoundedtirzepatide — Itchy injection lumps at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Reddit r/PeptideSource — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Reddit r/PeptideSource — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Reddit r/semaglutide — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Reddit r/semaglutide — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Reddit r/WegovyWeightLoss — Do you guys get these itchy spots ?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Reddit r/WegovyWeightLoss — Itchy injection sites at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Reddit r/WegovyWeightLoss — Itchy injection lumps at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

PubMed — Tirzepatide once weekly for the treatment of obesity in people with type 2

Lancet. 2023 Aug 19;402(10402):613-626. doi: 10.1016/S0140-6736(23)01200-X. Epub 2023 Jun 26. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. Garvey WT(1), Frias JP(2), Jastreboff AM(3), le Roux CW(4), Sattar N(5), Aizenberg D(6), Mao H(7), Zhang S(7), Ahmad NN(7), Bunck MC(7), Benabbad I(7), Zhang XM(7); SURMOUNT-2 investigators. Collaborators: Abalos FH, Manghi

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Just took my third shot. I am 60 years old, female, 5'7'', and weigh 295. I lost 5 pounds by the 2nd shot. Maybe that's not terribly impressive, but I don't want to lose quickly. Here's what I think is an absolute miracle with Zepbound: NO HEAD HUNGER! For the first time (probably in my life), I don't think about food. I don't crave junk food, I get full very quickly and can only eat small amounts. I h

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I’ve been on Ozempic for 4 weeks. I am so glad that my doctor sat me down and told me what to expect. She also asked if I could handle it. She said that if you can make it through the 4th week, I promise it will get better. She was right. I was pretty sick the first two weeks. I learned that it had a lot to do with me trying to eat my normal intake of food. Once I started to catch a clue and make my portions smaller, I

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "6 months. -65 pounds. Hypertension gone. Pre-Diabetes gone. Sleep apnea gone. Lower leg skin breakdown gone. Slow progress now. I must fight the return of old eating habits. Wegovy is not for wimps. But if you really want to lose weight, this is the way to go. This is like bariatric surgery in a small needle."

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 9 / 10 "Started taking this medication off label for weight loss only. I am not diabetic. Started on Aug 30, 2020. First 2 weeks I had some mild nausea, nothing terrible, and some mild dizziness. The past 2 weeks, I have had no symptoms. I definitely cannot eat what I used to, or you will feel sick. I am doing the weekly injection at 0.25 along with Weight Watchers, and in the past 26 days, I have lost 10.5 lbs :). My sweet tooth cravings are pretty much

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 9 / 10 "Started taking this medication off label for weight loss only. I am not diabetic. Started on Aug 30, 2020. First 2 weeks I had some mild nausea, nothing terrible, and some mild dizziness. The past 2 weeks, I have had no symptoms. I definitely cannot eat what I used to, or you will feel sick. I am doing the weekly injection at 0.25 along with Weight Watchers, and in the past 26 days, I have lost 10.5 lbs :). My sweet tooth cravings are pretty much

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have been taking Wegovy for 1 week and 2 days. Only had the 0.25 dosage. I have had no side effects and I have lost 8 lbs. I am hoping as I increase the dosage I remain free of side effects and the weight continues to fall off. I will continue to leave feedback so people can see how it is working and hopefully it will help them make a decision. I almost didn't go through with the first injection beca

Reddit r/compoundedtirzepatide — started a new job and i’ve been calling in at least once a week.

i’m 18 from New Zealand and i’ve started a new job at a hardware store about a month ago, i recently graduated in november and now im doing 45 hours a week right on the spot which has been burning me out. i dont have a car so im having to take 2 busses and wake up at 5am before the sun comes up, and getting home at 7:30pm when the sun is down. i wake up everyday trying to push myself to get up but theres some days where i genuinely cant do it. i made the decision to talk to my boss since i cant

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Reddit r/compoundedtirzepatide — I Didn’t Realize How Tired I Was Until I Slowed Down

Some days I’d wake up feeling heavy and call it laziness. I’d lie there, already behind on the day, already thinking about everything I wasn’t doing. By evening, that feeling turned into guilt. The fix, in my head, was always the same: more discipline, more effort, try harder tomorrow. A few days ago, I stopped pushing for once. I didn’t try to turn the day around or compensate for it later. I rested and left it at that. That’s when something clicked. The problem wasn’t laziness. I’d been

Twitter/X — “Ozempic itch” is all over social media but should you be worried? Some people u

Tweet/X post: “Ozempic itch” is all over social media but should you be worried? Some people using GLP-1 medications may experience mild injection-site itching or redness. According to Dr. Anne Peters, these reactions usually resolve within a few days. If itching spreads - x.com Published: Tue, 10 Mar 2026 07:00:00 GMT “Ozempic itch” is all over social media but should you be worried? Some people using GLP-1 medications may experience mild injection-site itching or redness. According to Dr. An

Quora — Has anyone had any experiences with the diet drug saxenda? - Quora

Quora Q&A: Has anyone had any experiences with the diet drug saxenda? - Quora Published: Sat, 30 Apr 2016 07:00:00 GMT Has anyone had any experiences with the diet drug saxenda?  Quora

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "Started Saxenda January 1, 2020 at 300.4 lbs. To date February 21, I am down 44 lbs. 1000 to 1200 calories per day and 10k to 12k average # of steps per day. Cravings are gone low appetite, and nausea if I try to eat too much. Few side effects now but same as everyone else at the beginning. By the end of my 2nd script, I may be down 60 lbs and would like to stop shots for a while but concerned about gai

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "Started Saxenda January 1, 2020 at 300.4 lbs. To date February 21, I am down 44 lbs. 1000 to 1200 calories per day and 10k to 12k average # of steps per day. Cravings are gone low appetite, and nausea if I try to eat too much. Few side effects now but same as everyone else at the beginning. By the end of my 2nd script, I may be down 60 lbs and would like to stop shots for a while but concerned about gai

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started using Saxenda on June 2. I am 43 years old and my starting weight was 87.8 kg. My height is 172 cm and I’m very athletic. For the past two years, my weight started to slowly escalate from 73 kg to 87.8 kg. I’m not sure if that is due to hypothyroidism or age, but in either case I wasn’t very happy because no matter how much I was working out or dieting, my weight would increase. My doctor rec

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I've been on Saxenda for seven days. My starting weight was 186.4, and today I'm 181, that's >5 lbs in one week! I have had very, very mild nausea for a few minutes after the first dose, unusual taste in my mouth, I'm incredibly thirsty and have a dry mouth. I have lost my appetite and only feel the need to eat around dinner time. At this point, I have a nutritious soup and a slice of brown sourdough. I

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I've been on Saxenda for seven days. My starting weight was 186.4, and today I'm 181, that's >5 lbs in one week! I have had very, very mild nausea for a few minutes after the first dose, unusual taste in my mouth, I'm incredibly thirsty and have a dry mouth. I have lost my appetite and only feel the need to eat around dinner time. At this point, I have a nutritious soup and a slice of brown sourdough. I

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I am currently in week 3. I have lost 14 pounds. The side effects have been minimal, and are a little stronger on a day that I increase dosage. The notable side effects are a light nausea when it is time to eat, or after a meal in which I have eaten more than I should. I am incredibly pleased with the results of this medication. I feel good, and my stamina for exercise has increased. My blood pressure

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Thank you Zepbound for showing me what being full was. It's a whole new feeling. I have more pep in my step. Four weeks in, over 20 pounds lost. Bring on the 2024 weight loss journey!! (2.5 dose, going up next shot)"

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have been on the 15 mg/0.5 mL for the last four months and on Mounjaro for a total of ten months starting with the 2.5 mg dosage. Well, I have to say I love it. I had a bit of nausea in the beginning but that’s it, never had it again. I have lost a total of 115 lbs. I don’t just eat whatever I want though, I have mainly been eating chicken, eggs, and turkey with things like cauliflower rice and once

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Just took my third shot. I am 60 years old, female, 5'7'', and weigh 295. I lost 5 pounds by the 2nd shot. Maybe that's not terribly impressive, but I don't want to lose quickly. Here's what I think is an absolute miracle with Zepbound: NO HEAD HUNGER! For the first time (probably in my life), I don't think about food. I don't crave junk food, I get full very quickly and can only eat small amounts. I h

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have learned to manage side effects (constipation) with probiotics. This is the only thing that has allowed me to lose the weight I gained post-menopause. I was a size 22 and am now almost a size 10. My BMI went from 39 to just over 30, and I have about 25 more pounds to go. I lost 45 pounds currently. I am no longer taking medication for migraines, asthma, and chronic edema, and my BP medication has

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "315-pound man, 64 heavy drinker, quit all booze, gained weight. Began rowing machine daily, gained weight. Counted all calories, 2500/day, no loss. A1C not bad 7, went on Mounjaro lowest dose 2.5. Have lost 40 pounds (!) in two months, eat anything and everything just way less and no desire to snack between. Still losing a bit, but feel plateau, may ask for larger dose. A miracle, has changed my life m

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I am an African American female, 58 years old, 5’8” tall, weighed an unbelievable 270 lbs on 12/30/22. I asked my doctor if I could take this medication, and now here we are, 8 weeks later. I currently weigh 244.6 lbs. I lost 16 lbs in the first 3 weeks. I was extremely shocked and a little worried. My health is a constant concern, I suffer from chronic allergies, and frequently took steroid shots to ma

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I am an African American female, 58 years old, 5’8” tall, weighed an unbelievable 270 lbs on 12/30/22. I asked my doctor if I could take this medication, and now here we are, 8 weeks later. I currently weigh 244.6 lbs. I lost 16 lbs in the first 3 weeks. I was extremely shocked and a little worried. My health is a constant concern, I suffer from chronic allergies, and frequently took steroid shots to ma

EMA/EudraVigilance — Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (

Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists for Weight Loss: A Scoping Review - Cureus Source: Cureus Published: Wed, 13 Aug 2025 07:00:00 GMT Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists for Weight Loss: A Scoping Review  Cureus

ClinicalTrials.gov — Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Clinical trial: Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment NCT ID: NCT07226947 Status: RECRUITING Phase: NA Enrollment: 100 participants Conditions: Obesity, Body Composition Interventions: Smartwatch activity and body composition monitor, General guidance on recommended exercise Primary outcomes: Lean mass (kg) Secondary outcomes: Lean mass index (kg/m2); Appendicular lean mass index (kg/m2); Fat mass index (kg/m2); Fat mass (kg); Visceral adipose tissue (k

ClinicalTrials.gov — Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Clinical trial: Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment NCT ID: NCT07226947 Status: RECRUITING Phase: NA Enrollment: 100 participants Conditions: Obesity, Body Composition Interventions: Smartwatch activity and body composition monitor, General guidance on recommended exercise Primary outcomes: Lean mass (kg) Secondary outcomes: Lean mass index (kg/m2); Appendicular lean mass index (kg/m2); Fat mass index (kg/m2); Fat mass (kg); Visceral adipose tissue (k

Reuters — GLP-1 weight loss, side effects linked to genetic variations - Reuters

GLP-1 weight loss, side effects linked to genetic variations - Reuters Source: Reuters Published: Fri, 10 Apr 2026 20:08:12 GMT GLP-1 weight loss, side effects linked to genetic variations  Reuters

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 24M turning 25 soon. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyw

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Twitter/X — Learn about some effective ways to manage common GLP-1 side effects—like nausea

Tweet/X post: Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCare - x.com Published: Fri, 16 May 2025 07:00:00 GMT Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCa

Twitter/X — Learn about some effective ways to manage common GLP-1 side effects—like nausea

Tweet/X post: Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCare - x.com Published: Fri, 16 May 2025 07:00:00 GMT Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCa

Twitter/X — GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs w

Tweet/X post: GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects both mild and serious to taking GLP-1 drugs, including nausea and dizziness t - x.com Published: Wed, 01 Apr 2026 06:17:59 GMT GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects b

Twitter/X — GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs w

Tweet/X post: GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects both mild and serious to taking GLP-1 drugs, including nausea and dizziness t - x.com Published: Wed, 01 Apr 2026 06:17:59 GMT GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects b

Twitter/X — Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Su

Tweet/X post: Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio) #GLP1 #GutHealth #Semaglutide #LowFODMAP - x.com Published: Sat, 21 Mar 2026 07:00:00 GMT Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio

Twitter/X — Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Su

Tweet/X post: Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio) #GLP1 #GutHealth #Semaglutide #LowFODMAP - x.com Published: Sat, 21 Mar 2026 07:00:00 GMT Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio

Twitter/X — JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely

Tweet/X post: JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely walk. Instead I am reduced to crawling on my hands and knees. I never saw this devastating side-effect coming... - x.com Published: Wed, 03 Dec 2025 08:00:00 GMT JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely walk. Instead I am reduced to crawling on my hands and knees. I never saw this devastating side-effect coming...  x.com

Twitter/X — Ozempic and Mounjaro linked to vision loss—new study Research has connected the

Tweet/X post: Ozempic and Mounjaro linked to vision loss—new study Research has connected the diabetes and weight-loss drugs Ozempic and Mounjaro to a rare eye condition called NAION, which can cause permanent vision loss. Although diabetes itself can cause blin - x.com Published: Tue, 11 Feb 2025 08:00:00 GMT Ozempic and Mounjaro linked to vision loss—new study Research has connected the diabetes and weight-loss drugs Ozempic and Mounjaro to a rare eye condition called NAION, which can cause

Twitter/X — Is a new weight-loss drug making people fall out of love? A recent TikTok video

Tweet/X post: Is a new weight-loss drug making people fall out of love? A recent TikTok video shows a man in a black baseball cap, with text over the video stating: “strange effects of Reta” and “ruining relationships”. He is referring to retatrutide, an experimental weight-loss - x.com Published: Tue, 07 Apr 2026 07:39:45 GMT Is a new weight-loss drug making people fall out of love? A recent TikTok video shows a man in a black baseball cap, with text over the video stating: “strange effects o

Twitter/X — The weight you lose and the nausea you experience from GLP-1 drugs may be linked

Tweet/X post: The weight you lose and the nausea you experience from GLP-1 drugs may be linked to common gene variants, but they can’t fully explain why some people lose more weight than others - x.com Published: Wed, 08 Apr 2026 15:05:04 GMT The weight you lose and the nausea you experience from GLP-1 drugs may be linked to common gene variants, but they can’t fully explain why some people lose more weight than others  x.com

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I'm in my fifth week taking injections. I've been on 2000mg metformin daily for 4 years but my A1C has been creeping up over the last year (7.3) and my fasting blood sugars (morning) had averaged around 160 and almost never registering below 150 and too often above 170. Over the last 4 weeks, my fasting sugars have steadily dropped. Last week they averaged 116 and this week they are averaging 107. I've experienced sporadi

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I'm in my fifth week taking injections. I've been on 2000mg metformin daily for 4 years but my A1C has been creeping up over the last year (7.3) and my fasting blood sugars (morning) had averaged around 160 and almost never registering below 150 and too often above 170. Over the last 4 weeks, my fasting sugars have steadily dropped. Last week they averaged 116 and this week they are averaging 107. I've experienced sporadi

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 9 months now. My A1c's came down from 12 to 6.5. My sugar is always around 90-100 and never drops. I feel fantastic. I've dropped 60 lbs and eat when I want and never finish a meal. I ride my bike 20 miles with no issues."

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I have been on Byetta since August last year and except for some nausea and slight constipation have found it to be a miracle for me. My sugar levels have improved and also have halved my blood pressure medication. Also my eyesight has improved greatly. I have lost 30kg and am feeling great. Thanks Byetta!"

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I have been on Byetta since August last year and except for some nausea and slight constipation have found it to be a miracle for me. My sugar levels have improved and also have halved my blood pressure medication. Also my eyesight has improved greatly. I have lost 30kg and am feeling great. Thanks Byetta!"

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 18 months, and used Byetta for 8 months before that. I switched from the Byetta because I couldn't handle the digestive upset any more, but the results were amazing. My A1c has come down to the 5.7-5.9 level consistently. Fasting BG is in the 80s normally. I haven't had any of the stomach upset with Bydureon. The shots are a pain, and I don't think I like the pen very much since I can't control

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 18 months, and used Byetta for 8 months before that. I switched from the Byetta because I couldn't handle the digestive upset any more, but the results were amazing. My A1c has come down to the 5.7-5.9 level consistently. Fasting BG is in the 80s normally. I haven't had any of the stomach upset with Bydureon. The shots are a pain, and I don't think I like the pen very much since I can't control

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I have been on Bydureon since 11/12. My A1c has gone from 9.5 to 6.0, and I am off of all insulin. When I first started the med, I was 5'2" and 187 pounds. I am now just over 10 months later 138 lbs. This has worked miracles for me as none of the oral medications helped me at all. I have not had any side effects. The shot is a bit painful, but I've found if you let it warm up about 15 minutes, it's a little easier. I do

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I am enjoying the results of Bydureon - 5th shot is tomorrow. I've lost 19 lbs and sometimes have to make myself eat something. Bydureon is helping me eat very healthy, and I've lost my cravings for sweets and carbs. My sugars have dropped from 220-300 range to 90-110 range. I have energy to spare. I also take 500 mg of Metformin twice a day. No issues with lumps, but the medicine does burn at times when injected."

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I am enjoying the results of Bydureon - 5th shot is tomorrow. I've lost 19 lbs and sometimes have to make myself eat something. Bydureon is helping me eat very healthy, and I've lost my cravings for sweets and carbs. My sugars have dropped from 220-300 range to 90-110 range. I have energy to spare. I also take 500 mg of Metformin twice a day. No issues with lumps, but the medicine does burn at times when injected."

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Well, this is my second review on this drug. I am now on my 3rd week of taking Trulicity and can happily report I’m getting on brilliantly, no more side effects, not that there were many anyway, just slight wind and nausea. Very, very easy and painless to inject. Sugar levels gone from 18 to 5.5-6, therefore being able to reduce my daily insulin dose significantly. Appetite cut in half, not really losing weight yet, bu

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Well, this is my second review on this drug. I am now on my 3rd week of taking Trulicity and can happily report I’m getting on brilliantly, no more side effects, not that there were many anyway, just slight wind and nausea. Very, very easy and painless to inject. Sugar levels gone from 18 to 5.5-6, therefore being able to reduce my daily insulin dose significantly. Appetite cut in half, not really losing weight yet, bu

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Trulicity last week. I was a bit nervous before using it because so many people complained of gastric distress. I am very pleased to say I had no problem with the Trulicity. No gastric issues, the injection is painless, and best of all, my blood sugar is actually in a normal range. I'm so glad my physician suggested I try Trulicity."

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Update to earlier post. It's now been 5 weeks since starting Trulicity and happy to report the side effects have mostly disappeared. My appetite is very subdued. Blood sugar levels ranging between 3.4 and 6.5. Weight has reduced further. Another 7 lb shed in 2 weeks. Total weight loss now 17 pounds. All very positive. This drug works great for me. Everyone reacts differently to new meds but it's so worth a go. Make it

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "No need for details. I experienced the same awful side effects as many of the posters. So I quit the drug and went on a low-carb diet (little or no grains, starches, or sugar) and started walking 20 minutes every day as fast as I could. Lost 40 lbs. A1C went from 8.0 to 5.5. Never felt better. But I am still diabetic, meaning I cannot go back to my old ways. If I can do it, you can do it. Oh, and the money I am saving!"

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 5 / 10 For Type 2 Diabetes "I must say you guys were scaring me about the negative side effects, so I was weighing up whether or not to start. I realized that I am more than a conqueror, and can overcome any undesirable side effects that come up. Well, about 4 hours later and time to eat, the yucky stomach started. I thought, is it just my mind or is it really the new meds kicking in. I didn't eat much, a good thing. HERE IS WHAT TOOK THE SICK FEE

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "My husband of over fifty years was put on this drug at the beginning of 2020. He was over 270 pounds, and his A1C was over 11. The doctor was desperate. My husband experienced horrible nausea and abdominal pain. He began to lose weight but not as fast as the doctor wanted. He was put on concentrated insulin twice a day. He started becoming sicker. He was taken to the ER in August of 2020. He was placed on a ventilator f

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "My husband of over fifty years was put on this drug at the beginning of 2020. He was over 270 pounds, and his A1C was over 11. The doctor was desperate. My husband experienced horrible nausea and abdominal pain. He began to lose weight but not as fast as the doctor wanted. He was put on concentrated insulin twice a day. He started becoming sicker. He was taken to the ER in August of 2020. He was placed on a ventilator f

Guidelines/NICE website — Tirzepatide for managing overweight and obesity - NICE website

Tirzepatide for managing overweight and obesity - NICE website Source: NICE website Published: Mon, 23 Dec 2024 08:00:00 GMT Tirzepatide for managing overweight and obesity  NICE website

MHRA/The Guardian — Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warn

Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warns - The Guardian Source: The Guardian Published: Thu, 29 Jan 2026 08:00:00 GMT Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warns  The Guardian

MHRA/Medscape — MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs - Medscape

MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs - Medscape Source: Medscape Published: Fri, 30 Jan 2026 08:00:00 GMT MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs  Medscape

MHRA/European Medical Journal — Acute Pancreatitis Warnings Strengthened on GLP-1RAs - European Medical Journal

Acute Pancreatitis Warnings Strengthened on GLP-1RAs - European Medical Journal Source: European Medical Journal Published: Sat, 07 Feb 2026 08:00:00 GMT Acute Pancreatitis Warnings Strengthened on GLP-1RAs  European Medical Journal

MHRA/Pulse Today — MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis - P

MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis - Pulse Today Source: Pulse Today Published: Fri, 30 Jan 2026 08:00:00 GMT MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis  Pulse Today

PubMed India — 10.1001/jamainternmed.2025.3599.

JAMA Intern Med. 2025 Oct 1;185(10):1206-1217. doi: 10.1001/jamainternmed.2025.3599. Oral Semaglutide in an East Asian Population With Overweight or Obesity, With or Without Type 2 Diabetes: The OASIS 2 Randomized Clinical Trial. Kadowaki T(1), Heftdal LD(2), Ko HJ(3), Overvad M(2), Shimomura I(4), Thamattoor UK(5), Kim KK(6); OASIS 2 Investigators. Collaborators: Kunishige H, Okude J, Sato N, Takeda S, Uemura K, Osonoi T, Isshiki S, Ito N, Naito H, Oka N, Hosoya M, Saito M, Takizawa H, A

Think Global Health — The Mental Health Effects of Ozempic and GLP-1 Drugs - Think Global Health

The Mental Health Effects of Ozempic and GLP-1 Drugs - Think Global Health Source: Think Global Health Published: Thu, 04 Dec 2025 08:00:00 GMT The Mental Health Effects of Ozempic and GLP-1 Drugs  Think Global Health

FDA FAERS — semaglutide — OFF LABEL USE

FDA adverse event reports for semaglutide: OFF LABEL USE reported 6855 times out of 99460 total reports (6.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Reddit r/compoundedtirzepatide — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Reddit r/compoundedtirzepatide — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Reddit r/compoundedtirzepatide — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Reddit r/compoundedtirzepatide — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Reddit r/semaglutide — Extreme Fatigue

Currently 8 weeks pregnant and I don’t have much symptoms just sore breasts and increased appetite. The nausea has subsided ALOT, BUT the fatigue is crazy…. I can barely even get up to go take a shower because it sounds like too much work. I am someone that is constantly on the go, loves to cook and I can’t even move from the couch to get to my bed!!! It is so bad I am ordering pre cooked rice and chicken breast from chic fila because there is just no energy. Is this normal? When will it passss

Reddit r/semaglutide — Extreme Fatigue

Currently 8 weeks pregnant and I don’t have much symptoms just sore breasts and increased appetite. The nausea has subsided ALOT, BUT the fatigue is crazy…. I can barely even get up to go take a shower because it sounds like too much work. I am someone that is constantly on the go, loves to cook and I can’t even move from the couch to get to my bed!!! It is so bad I am ordering pre cooked rice and chicken breast from chic fila because there is just no energy. Is this normal? When will it passss

Reddit r/WegovyWeightLoss — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Reddit r/WegovyWeightLoss — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Reddit r/WegovyWeightLoss — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Reddit r/WegovyWeightLoss — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

PubMed — Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity.

N Engl J Med. 2024 Oct 3;391(13):1193-1205. doi: 10.1056/NEJMoa2404881. Epub 2024 Jun 21. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. Malhotra A(1), Grunstein RR(1), Fietze I(1), Weaver TE(1), Redline S(1), Azarbarzin A(1), Sands SA(1), Schwab RJ(1), Dunn JP(1), Chakladar S(1), Bunck MC(1), Bednarik J(1); SURMOUNT-OSA Investigators. Collaborators: Eckert DJ, Grunstein RR, Santos Canani LH, Halpern B, Cercato C, Delgado Fernandes M, Alves BB, Kerr Saraiva JF, Reis

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Emotional blunting / Reduced pleasure: 12%. Widely discussed on Reddit and forums but absent from clinical trial data. Users describe feeling 'flat' — less joy from food but also from music, socialising, and other activities. Some find it distressing, others see it as a neutral side effect.

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 2% at low dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 2% at low dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Reddit r/Ozempic emotional blunting megathread (2024-2026)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Reddit r/Ozempic emotional blunting megathread (2024-2026)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.