Sources Database

Every data point behind our side effects predictor. Fully transparent. You can see exactly where our data comes from.

717

Total data points

91

Clinical study

467

User report

78

News source

81

Regulatory data

User reportabdominal_pain4%severe

Twitter/X — Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you

Tweet/X post: Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you start prescribing them to nearly 40 million Americans, you have to expect complications and side effects, like with any medication. About 4% of people experience serious gastr - x.com Published: Tue, 03 Feb 2026 08:00:00 GMT Ozempic and other GLP1 drugs have been helpful for a lot of people. But when you start prescribing them to nearly 40 million Americans, you have to expect complications and side

Collected: 5/1/2026n=40000000Extraction: medium
Regulatory datavision_loss

EMA/EudraVigilance — EU safety committee says semaglutide carries 'very rare' risk of vision loss - F

EU safety committee says semaglutide carries 'very rare' risk of vision loss - FirstWord Pharma Source: FirstWord Pharma Published: Fri, 06 Jun 2025 07:00:00 GMT EU safety committee says semaglutide carries 'very rare' risk of vision loss  FirstWord Pharma

Collected: 5/1/2026Extraction: low
Clinical studynausea

Cochrane/Nature — A systematic review and meta-analysis of the efficacy and safety of pharmacologi

A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults - Nature Source: Nature Published: Thu, 02 Oct 2025 07:00:00 GMT A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults  Nature

Collected: 5/1/2026Extraction: low
News sourceweight_regain

TCTMD.com — Weight Regained Within 18 Months of Stopping GLP-1 Drugs - TCTMD.com

Weight Regained Within 18 Months of Stopping GLP-1 Drugs - TCTMD.com Source: TCTMD.com Published: Thu, 08 Jan 2026 08:00:00 GMT Weight Regained Within 18 Months of Stopping GLP-1 Drugs  TCTMD.com

Collected: 5/1/2026Extraction: low
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Injection Site Redness Doesn’t Go Away

Does anyone have the same? Been using Reta since November 2025 and last 10 injections are red. I use sterile everything, made sure to do so. Actually it was 2 before visible and now I see all 10 they seem to appear more red in the past couple weeks. Wondering if any advice how to get rid of them.

Collected: 5/1/2026n=1Extraction: high
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — If Saxenda/Liraglutide has been feeling less effective, make sure you're rotatin

The past few months I've been disheartened by a progressive reduction in efficacy from Saxenda. Some food noise began coming back, and the appetite reduction has felt lessened. It turns out, I may have been causing this issue myself. I've been injecting Saxenda into the same spot every day for months, oblivious to the fact that you're supposed to rotate injection sites. When I touch that area of my stomach, I can feel a slightly hard little lump, but I didn't think very much of it until I read

Collected: 5/1/2026Extraction: high
User reportreduced_appetite

Reddit r/compoundedtirzepatide — If Saxenda/Liraglutide has been feeling less effective, make sure you're rotatin

The past few months I've been disheartened by a progressive reduction in efficacy from Saxenda. Some food noise began coming back, and the appetite reduction has felt lessened. It turns out, I may have been causing this issue myself. I've been injecting Saxenda into the same spot every day for months, oblivious to the fact that you're supposed to rotate injection sites. When I touch that area of my stomach, I can feel a slightly hard little lump, but I didn't think very much of it until I read

Collected: 5/1/2026Extraction: high
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Blood Test for Peptide Stack

37, 193, 5'-10" male, on a pretty popular peptide stack consisting of Retatrutide (2 months in at 4mg), Tessamorelin (3 weeks in), Ipamorelin, GLOW. Did Mots-c for 1 month at 5mg a day 6 days a week, but stopped due to injection site lumps and itching. About to also add Pinealon and Epithalon for 20 and 10 days respectively. I did get these all tested for Endotoxin, Sterility and heavy metals in addition to mass analysis. Probably not wise to inject peps... but if im gonna do this, I'd like to d

Collected: 5/1/2026Dose: highn=1Extraction: high
User reportfatigue

Reddit r/PeptideSource — Workout Suggestions

Hi everyone! I wanted to ask what your workout routines are? I have crazy fatigue and going to the gym can be quite difficult. If I go three times in one week, I usually end up needing the entire next week to recover because I’ve completely drained my energy so I wanted to ask if you guys have any suggestions for working out while having endo.

Collected: 5/1/2026Extraction: low
User reportfatigue

Reddit r/semaglutide — Workout Suggestions

Hi everyone! I wanted to ask what your workout routines are? I have crazy fatigue and going to the gym can be quite difficult. If I go three times in one week, I usually end up needing the entire next week to recover because I’ve completely drained my energy so I wanted to ask if you guys have any suggestions for working out while having endo.

Collected: 5/1/2026Extraction: high
User reportweight_regain

Twitter/X — I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effe

Tweet/X post: I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effect I'd never heard of... and doctors say it's now on the rise - x.com Published: Mon, 25 Aug 2025 07:00:00 GMT I lost nine stone on Mounjaro but then I was hit with this disfiguring side-effect I'd never heard of... and doctors say it's now on the rise  x.com

Collected: 4/30/2026Extraction: low
User reportno_side_effects_reported

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I have taken Bydureon for about 3 months. My blood sugar has gone from over 200 to 125-180, which is a nice improvement. I do not yet know what has happened to my A1c. I inject the Bydureon into my thigh. I alternate sides each week so each thigh has two weeks to recover. I have had no side effects. I have been trying to lose weight in 2014. So far, I am down 14 pounds from 179 to 165 pounds."

Collected: 4/30/2026n=1Extraction: high
Regulatory dataabdominal_pain

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

Collected: 4/30/2026Extraction: low
Regulatory datavomiting

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

Collected: 4/30/2026Extraction: low
Regulatory datadiarrhea

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

Collected: 4/30/2026Extraction: low
Regulatory datanausea

WHO/Medscape — GI Safety Similar for Popular Weight-Loss Drugs - Medscape

GI Safety Similar for Popular Weight-Loss Drugs - Medscape Source: Medscape Published: Tue, 04 Nov 2025 08:00:00 GMT GI Safety Similar for Popular Weight-Loss Drugs  Medscape

Collected: 4/30/2026Extraction: low
News sourcenausea

India News — India’s doctors sound alarm over boom in availability of weight loss jabs - The

India’s doctors sound alarm over boom in availability of weight loss jabs - The Guardian Published: Sun, 21 Dec 2025 08:00:00 GMT India’s doctors sound alarm over boom in availability of weight loss jabs  The Guardian

Collected: 4/30/2026Extraction: low
User reportnauseamild

Reddit r/Ozempic — Pancreatitis

I got hospitalized for acute pancreatitis at 23 last year for 6 days and later relapsed a month later and until I went back again for only 4 days in February but the pain wasn't as bad. I started binge drinking again and was on a bender this past weekend while at an event in my city and vented/crying to my mom about personal issues and I shared embarrassing texts to my sister (it wasn't really embarrassing in hindsight it was just me showing her my art and my favorite songs and we talked for hou

Collected: 4/30/2026n=1Extraction: low
User reportpancreatitissevere

Reddit r/Ozempic — Pancreatitis

I got hospitalized for acute pancreatitis at 23 last year for 6 days and later relapsed a month later and until I went back again for only 4 days in February but the pain wasn't as bad. I started binge drinking again and was on a bender this past weekend while at an event in my city and vented/crying to my mom about personal issues and I shared embarrassing texts to my sister (it wasn't really embarrassing in hindsight it was just me showing her my art and my favorite songs and we talked for hou

Collected: 4/30/2026n=1Extraction: medium
User reportpancreatitis

Reddit r/Ozempic — Emergency room/hospital for trans person

​ So I'm needing to go to the hospital/emergency room. I think I have pancreatitis. I have blue cross blue shield. I'm a trans woman. What hospital has good lgbt care. Had a really bad experience with Kaiser last year where I was treated horribly and put in an unsafe situation by staff. I have new insurance now. I'm nervous and scared to go to a hospital again but need help. Any recommendations on which to go to as a trans person? Will probably go to the ER tomorrow when my partner

Collected: 4/30/2026Extraction: medium
User reportemotional_blunting

Reddit r/Mounjaro — Sudden shift to happiness (does mention talk of suicide.)

I am now happy I guess, which is pretty awesome cause being happy, smiling, randomly is nice, cause like a month\~ ago I absolutely spiraled, and was realistically, not gonna last long, and right as I got absolutely ***miserable*** (prolly would’ve killed myself the next day or the next few.) in the next day, feeling ok-ish early in the day, got really, REALLY *happy* later in the day, where I literally described it as drugged and couldn’t stop talking about it, and ever since then I’ve felt mi

Collected: 4/30/2026Extraction: low
User reportpancreatitis

Reddit r/intermittentfasting — Emergency room/hospital for trans person

​ So I'm needing to go to the hospital/emergency room. I think I have pancreatitis. I have blue cross blue shield. I'm a trans woman. What hospital has good lgbt care. Had a really bad experience with Kaiser last year where I was treated horribly and put in an unsafe situation by staff. I have new insurance now. I'm nervous and scared to go to a hospital again but need help. Any recommendations on which to go to as a trans person? Will probably go to the ER tomorrow when my partner

Collected: 4/30/2026Extraction: low
Clinical studynausea

PubMed — Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis.

N Engl J Med. 2024 Oct 31;391(17):1573-1583. doi: 10.1056/NEJMoa2403664. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis. Bliddal H(1), Bays H(1), Czernichow S(1), Uddén Hemmingsson J(1), Hjelmesæth J(1), Hoffmann Morville T(1), Koroleva A(1), Skov Neergaard J(1), Vélez Sánchez P(1), Wharton S(1), Wizert A(1), Kristensen LE(1); STEP 9 Study Group. Collaborators: Akhras R, Dzongowski P, Lowe D, Tytus R, Wharton S, Londoño Patiño J, Jaller Raad J, Vélez Sánchez P, Hau

Collected: 4/30/2026Extraction: low
User reportemotional_blunting

Twitter/X — Some patients have reported a negative experience on GLP-1s -- a sort of emotion

Tweet/X post: Some patients have reported a negative experience on GLP-1s -- a sort of emotional flattening colloquially referred to as "Ozempic personality." Read more at: - x.com Published: Sun, 26 Apr 2026 17:06:00 GMT Some patients have reported a negative experience on GLP-1s -- a sort of emotional flattening colloquially referred to as "Ozempic personality." Read more at:  x.com

Collected: 4/28/2026Extraction: medium
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Accidentally tasted t and it was awful

i do subq injections and on my last injection it bled a little more than normal, drop of blood came from the injection site and on instinct i wiped it on my finger & put it in my mouth. it was so bad. It tasted like what i imagine the bottom of a shoe tastes like after going on a long hike and stepping in dog shit. Like how dirt tastes if the dirt was evil and something died in it. Do not put t in your mouth under any conditions. thought you guys might want to hear lol

Collected: 4/28/2026n=1Extraction: high
User reportinjection_site_reaction

Reddit r/WegovyWeightLoss — Accidentally tasted t and it was awful

i do subq injections and on my last injection it bled a little more than normal, drop of blood came from the injection site and on instinct i wiped it on my finger & put it in my mouth. it was so bad. It tasted like what i imagine the bottom of a shoe tastes like after going on a long hike and stepping in dog shit. Like how dirt tastes if the dirt was evil and something died in it. Do not put t in your mouth under any conditions. thought you guys might want to hear lol

Collected: 4/28/2026n=1Extraction: medium
User report

Quora — I am diabetic 8/10. What medicine should I take now? - Quora

Quora Q&A: I am diabetic 8/10. What medicine should I take now? - Quora Published: Thu, 17 Apr 2025 07:00:00 GMT I am diabetic 8/10. What medicine should I take now?  Quora

Collected: 4/27/2026Extraction: low
News sourceweight_regain

Science Daily — Simple “gut reset” may stop weight gain after Ozempic or Wegovy - Science Daily

Simple “gut reset” may stop weight gain after Ozempic or Wegovy - Science Daily Source: Science Daily Published: Thu, 23 Apr 2026 06:46:53 GMT Simple “gut reset” may stop weight gain after Ozempic or Wegovy  Science Daily

Collected: 4/27/2026Extraction: medium
News sourcediarrhea

The 19th News — Sleepless nights, diapers and GLP-1s: More people are turning to weight loss dru

Sleepless nights, diapers and GLP-1s: More people are turning to weight loss drugs after having babies - The 19th News Source: The 19th News Published: Thu, 23 Apr 2026 13:12:04 GMT Sleepless nights, diapers and GLP-1s: More people are turning to weight loss drugs after having babies  The 19th News

Collected: 4/27/2026Extraction: low
User reportreduced_appetitemoderate

Reddit r/compoundedtirzepatide — Sleeping 11 hours a day and still tired

(24F) The past few months, I’ve been hit with this extreme, debilitating fatigue making it hard to do anything. Even after getting 10-11 hours of sleep everyday, I feel tired. Also, recently, I’ve been getting full really easily (after just a couple bites of food). I still try to eat a normal amount so that I get enough calories and nutrients. The fatigue came first so I don’t think this is the cause of the fatigue. I used to be a fairly active, high-energy person, so this has been especially de

Collected: 4/27/2026n=1Extraction: high
User reportfatiguesevere

Reddit r/compoundedtirzepatide — Sleeping 11 hours a day and still tired

(24F) The past few months, I’ve been hit with this extreme, debilitating fatigue making it hard to do anything. Even after getting 10-11 hours of sleep everyday, I feel tired. Also, recently, I’ve been getting full really easily (after just a couple bites of food). I still try to eat a normal amount so that I get enough calories and nutrients. The fatigue came first so I don’t think this is the cause of the fatigue. I used to be a fairly active, high-energy person, so this has been especially de

Collected: 4/27/2026n=1Extraction: high
User reportfatigue

Reddit r/compoundedtirzepatide — Is this RLS or something else?

I had covid in december and i am now still in recovery from post covid syndrome. I suffer from headaches, breathing problems and fatigue. But the worst part is i cannot fall asleep. I have sleeping meds and melatonin but as soon as i go to bet my body decides i need to go and walk. My legs feel normal but i have this weird muscle tension and tingling in my lower belly that is sooo awful that it makes me wanna scream. It only stops when i walk. I have occasionally had this ever since i was a ch

Collected: 4/27/2026Extraction: low
User reportheadache

Reddit r/compoundedtirzepatide — Is this RLS or something else?

I had covid in december and i am now still in recovery from post covid syndrome. I suffer from headaches, breathing problems and fatigue. But the worst part is i cannot fall asleep. I have sleeping meds and melatonin but as soon as i go to bet my body decides i need to go and walk. My legs feel normal but i have this weird muscle tension and tingling in my lower belly that is sooo awful that it makes me wanna scream. It only stops when i walk. I have occasionally had this ever since i was a ch

Collected: 4/27/2026Extraction: low
User reportemotional_blunting

Reddit r/Mounjaro — I think its just depression + self hatred but just wanting to know if others fee

Recently ive not understood human feelings or processes, it’s not like I never felt them I just don’t understand them in an odd way. I feel hunger, I understand that I must eat to gain energy to survive yet I dislike that I must and I have to I dont understand why but all the same feel and know why, yet I also feel great pleasure for consuming food and quite enjoy so, yet I don’t like that I consume I quite wish I could just not. As for emotions, for example anxiety confuses me, my mind and body

Collected: 4/26/2026Extraction: medium
Clinical studyhair_loss

PubMed — Alopecia and Semaglutide: Connecting the Dots for Patient Safety.

J Cosmet Dermatol. 2025 Mar;24(3):e70125. doi: 10.1111/jocd.70125. Alopecia and Semaglutide: Connecting the Dots for Patient Safety. Haykal D(1). Author information: (1)Centre Laser Palaiseau, private practice, Palaiseau, France. DOI: 10.1111/jocd.70125 PMCID: PMC11909624 PMID: 40087997 Conflict of interest statement: The author declares no conflicts of interest.

Collected: 4/26/2026Extraction: medium
Clinical studyhair_loss

PubMed — 10.1111/jdv.20197. Epub 2024 Jun 24.

J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e153-e154. doi: 10.1111/jdv.20197. Epub 2024 Jun 24. Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023. Godfrey H(1), Leibovit-Reiben Z(1), Jedlowski P(2), Thiede R(2). Author information: (1)University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA. (2)Division of Dermatology, University of Arizona College of Medicine

Collected: 4/26/2026Extraction: medium
Clinical studyhair_loss

PubMed — 10.1111/jdv.20197. Epub 2024 Jun 24.

J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e153-e154. doi: 10.1111/jdv.20197. Epub 2024 Jun 24. Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023. Godfrey H(1), Leibovit-Reiben Z(1), Jedlowski P(2), Thiede R(2). Author information: (1)University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA. (2)Division of Dermatology, University of Arizona College of Medicine

Collected: 4/26/2026Extraction: medium
Clinical studyhair_loss

PubMed — Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use:

Cureus. 2025 Sep 16;17(9):e92454. doi: 10.7759/cureus.92454. eCollection 2025 Sep. Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review. Alsuwailem OA(1), Alanazi R(2), Almutairi HM(3), Asiree RH(3), Almutairi W(4), Almutairi TM(3), Zamandar A(4), Alkhames S(5). Author information: (1)College of Medicine and Surgery, King Faisal University, Al-Ahsa, SAU. (2)College of Medicine, Dar Al Uloom University, Riyadh, SAU. (3)College of Medicine, Majm

Collected: 4/26/2026Extraction: medium
User reportvomiting

Twitter/X — A large study of 23andMe customers found variants in two genes that play a role

Tweet/X post: A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting. - x.com Published: Fri, 17 Apr 2026 17:25:14 GMT A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting.  x.com

Collected: 4/25/2026Extraction: low
User reportnausea

Twitter/X — A large study of 23andMe customers found variants in two genes that play a role

Tweet/X post: A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting. - x.com Published: Fri, 17 Apr 2026 17:25:14 GMT A large study of 23andMe customers found variants in two genes that play a role in weight loss, and nausea and vomiting.  x.com

Collected: 4/25/2026Extraction: low
User reportnausea

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Sun, 19 Apr 2026 23:00:13 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

Collected: 4/25/2026Extraction: medium
Regulatory dataemotional_blunting

EMA/EudraVigilance — European drugs regulator to review Wegovy, Ozempic following reports of suicidal

European drugs regulator to review Wegovy, Ozempic following reports of suicidal thoughts - CNBC Source: CNBC Published: Mon, 10 Jul 2023 07:00:00 GMT European drugs regulator to review Wegovy, Ozempic following reports of suicidal thoughts  CNBC

Collected: 4/25/2026Extraction: low
News sourceweight_regain

Docwire News — Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawa

Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawal - Docwire News Source: Docwire News Published: Fri, 24 Apr 2026 18:27:07 GMT Duodenal Mucosal Resurfacing May Prevent Weight Regain Following GLP-1 Withdrawal  Docwire News

Collected: 4/25/2026Extraction: low
News sourcemuscle_loss

Wiley — Semaglutide impacts skeletal muscle to a similar extent as caloric restriction i

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet-induced obesity - Wiley Source: Wiley Published: Mon, 22 Sep 2025 07:00:00 GMT Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet-induced obesity  Wiley

Collected: 4/25/2026Extraction: medium
News sourcemuscle_losssignificant

UNC Health — New Study Finds Weight Loss Causes Significant Muscle Loss - UNC Health

New Study Finds Weight Loss Causes Significant Muscle Loss - UNC Health Source: UNC Health Published: Fri, 17 Apr 2026 16:01:26 GMT New Study Finds Weight Loss Causes Significant Muscle Loss  UNC Health

Collected: 4/25/2026Extraction: low
News sourceemotional_blunting

MedPage Today — 'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s? -

'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s? - MedPage Today Source: MedPage Today Published: Thu, 23 Apr 2026 21:43:48 GMT 'Ozempic Personality': Is Emotional Flattening Another Side Effect of GLP-1s?  MedPage Today

Collected: 4/25/2026Extraction: medium
Regulatory dataweight_loss13%

FDA FAERS — exenatide — WEIGHT DECREASED

FDA adverse event reports for exenatide: WEIGHT DECREASED reported 12125 times out of 94694 total reports (12.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/24/2026n=94694Extraction: high
User reportgallstones

Reddit r/loseit — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Collected: 4/24/2026Extraction: high
User reportacid_refluxsevere

Reddit r/loseit — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Collected: 4/24/2026Extraction: high
User reportemotional_blunting

Reddit r/Zepbound — Suffering from past few years from Cognitive Function which destroyed my life

Hi guys, I suffer from brutal 6-7 year old maladaptive daydreaming habit, overthinking, And 2024 at end year I went to pschiatrist and they gave me SSRIs and now I also suffer from PSSD, anhedonia, and emotional blunting. On top of it all these, I suffer from serious brain fog, short term and long term memory issues, can't execute any task or finish any task, numb brain, no creativity, not able to think at all, and my brain cant process any information and every small task looks very big to me.

Collected: 4/24/2026Extraction: low
User reportbloatingmild

Reddit r/Ozempic — 28M discomfort just under ribs on right side

Needless to say throwaway account. Some prior history. (28M) Gall bladder removal about a year ago Kidney stones every few years High bp (managed with losartan) Gerd (managed with omeprasole) And it has been noted on CT scans that I have fatty liver. (Trying to eat better and taking fish oil supplements to hope they help, lol) I weigh about 250 (working on losing weight, dropped about 8ish pounds in the last 2 months) 6ft Prior vitamin d deficiency (i take supplements for now) The

Collected: 4/24/2026n=1Extraction: medium
User reportabdominal_painmild

Reddit r/Ozempic — 28M discomfort just under ribs on right side

Needless to say throwaway account. Some prior history. (28M) Gall bladder removal about a year ago Kidney stones every few years High bp (managed with losartan) Gerd (managed with omeprasole) And it has been noted on CT scans that I have fatty liver. (Trying to eat better and taking fish oil supplements to hope they help, lol) I weigh about 250 (working on losing weight, dropped about 8ish pounds in the last 2 months) 6ft Prior vitamin d deficiency (i take supplements for now) The

Collected: 4/24/2026n=1Extraction: medium
User reportacid_refluxsevere

Reddit r/Ozempic — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Collected: 4/24/2026n=1Extraction: medium
User reportgallstones

Reddit r/Ozempic — So I took a LOA till figure things out.. turns out my gallbladder isn’t working.

So for context, long story short, I’m 20 years old and have been struggling with stomach issues since 2021, and just now getting some answers. I went on a leave of absence from my job to get said answers and I’m still slightly in denial I’m gonna need surgery. I go back to work and I wanted to start bringing lunch to work because money sucks right now and I’m not door dashing, it’s expensive. What’s the best food to bring or to cook? Even in general. I don’t know if it goes by person on what

Collected: 4/24/2026n=1Extraction: medium
User reportacid_refluxsevere

Reddit r/Ozempic — Unable to sleep due to reflux

21 F, 189 lbs, 5’2”, never smoked. I’m autistic(level 1) with severe ADHD and OCD, so I’m not very independent(live at home and still need mom’s permission for everything- I’m very smart and mentally competent but too scatterbrained to take care of myself because I just don’t remember to) and cannot drive. I take a LOT of meds but haven’t taken most of them in 24 hours, only Nexium(40mg a few hours ago), Pepcid(40mg recently), Zofran(I can’t remember the dosage but it’s just 1 little pill, a f

Collected: 4/24/2026n=1Extraction: high
User reportacid_reflux

Reddit r/Ozempic — acid reflux and working night shifts

Hi, I've been mostly lurking on this subreddit reading about everyones experience with GERD/LPR. I've been recently diagnosed and I'm trying to guide myself throught it - first with diet and taking care of myself properly. Decided to go on proper diet and I wanna try my best to stick to it, but there's a little problem - my work schedule. I work 2 night shifts, then I have 2 days off and then i work normal shifts that are up to 12 hours. How do i manage with my diet during the night? Does anyo

Collected: 4/24/2026Extraction: medium
User reportemotional_blunting

Reddit r/Mounjaro — Suffering from past few years from Cognitive Function which destroyed my life

Hi guys, I suffer from brutal 6-7 year old maladaptive daydreaming habit, overthinking, And 2024 at end year I went to pschiatrist and they gave me SSRIs and now I also suffer from PSSD, anhedonia, and emotional blunting. On top of it all these, I suffer from serious brain fog, short term and long term memory issues, can't execute any task or finish any task, numb brain, no creativity, not able to think at all, and my brain cant process any information and every small task looks very big to me.

Collected: 4/24/2026Extraction: low
User reportemotional_bluntingmoderate

Reddit r/Mounjaro — HELP. Went from months of emotional blunting to overwhelming emotion in a split

I’ve been on escitalopram since October, started out at 5mg and have been on 20mg since late November-early December. I’m generally doing a lot better than I was before, probably due to the emotional blunting, which I prefer to the multiple daily panic attacks and constant thoughts of ending things. The thing is I got some upsetting news at work yesterday and since then I feel completely overwhelmed with anger and sadness and can’t stop crying, which I hadn’t been able to do for months. Litera

Collected: 4/24/2026Extraction: medium
Clinical studynausea

PubMed — Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss

JAMA. 2021 Apr 13;325(14):1414-1425. doi: 10.1001/jama.2021.3224. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. Rubino D(1), Abrahamsson N(2), Davies M(3)(4), Hesse D(5), Greenway FL(6), Jensen C(5), Lingvay I(7), Mosenzon O(8), Rosenstock J(9), Rubio MA(10), Rudofsky G(11), Tadayon S(5), Wadden TA(12), Dicker D(13); STEP 4 Investigators. Collaborators: Friberg M, Sjödin

Collected: 4/24/2026Extraction: low
Regulatory datapancreatitissevere

MHRA/The Pharmaceutical Journal — ‘Life-threatening condition’ added to Mounjaro patient information leaflet - The

‘Life-threatening condition’ added to Mounjaro patient information leaflet - The Pharmaceutical Journal Source: The Pharmaceutical Journal Published: Fri, 28 Nov 2025 08:00:00 GMT ‘Life-threatening condition’ added to Mounjaro patient information leaflet  The Pharmaceutical Journal

Collected: 4/23/2026Extraction: medium
News source

India News — India's 'Mounjaro brides': weight-loss injections become part of pre-wedding pre

India's 'Mounjaro brides': weight-loss injections become part of pre-wedding preparation - Reuters Published: Sat, 04 Apr 2026 07:00:00 GMT India's 'Mounjaro brides': weight-loss injections become part of pre-wedding preparation  Reuters

Collected: 4/23/2026Extraction: low
User reportabdominal_painmild

Reddit r/PeptideSource — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: medium
User reportconstipationmoderate

Reddit r/PeptideSource — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: high
User reportabdominal_painsevere

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: medium
User reportreduced_appetitesevere

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportnauseamoderate

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportgallstonessevere

Reddit r/semaglutide — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportconstipationsevere

Reddit r/semaglutide — Reversal expectations

I had a perforated bowel due to SEVERE constipation six months ago. I woke up from surgery with a colostomy bag. Since then the whole goal of my recovery has been to have it reversed. I don't mean to offend anyone here, it just is what it is. My reversal is scheduled for May 1. Colonoscopy the day before. The surgery will be open because I have massive scarring; my incision was left open with a wound vac because it was such a mess in there. So the surgeon will go in through the same incision an

Collected: 4/23/2026n=1Extraction: medium
User reportabdominal_painmild

Reddit r/semaglutide — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: medium
User reportconstipationsevere

Reddit r/semaglutide — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: high
User reportdiarrheamild

Reddit r/semaglutide — Benefiber vs Metamucil

The doctor told me to take Senokot for constipation since at 6 weeks I’m still having trouble. It worked but caused me to rush to the bathroom and have messy poop. MiraLAX and even the MiraFast did that too. The nurse said she takes Metamusil but I chose to buy a store brand of Benifiber since it’s not gritty and mixes with anything. Though I have gluten issues and it says its gluten free by the way the make it, I’m afraid to take it. Is there anything that works and doesn’t cause diarrhea or ru

Collected: 4/23/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/semaglutide — Benefiber vs Metamucil

The doctor told me to take Senokot for constipation since at 6 weeks I’m still having trouble. It worked but caused me to rush to the bathroom and have messy poop. MiraLAX and even the MiraFast did that too. The nurse said she takes Metamusil but I chose to buy a store brand of Benifiber since it’s not gritty and mixes with anything. Though I have gluten issues and it says its gluten free by the way the make it, I’m afraid to take it. Is there anything that works and doesn’t cause diarrhea or ru

Collected: 4/23/2026n=1Extraction: high
User reportabdominal_pain

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportconstipation

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportdiarrhea

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportnausea

Reddit r/semaglutide — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportreduced_appetitesevere

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportnauseamoderate

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportgallstonessevere

Reddit r/loseit — A call for help - 11 months post-op

Hello, I’m F(27). I had my gallbladder removed on May 21, 2025. I had a lot of gallstones, and my gallbladder was twice the normal size. Before that, I had never had any health issues. A few weeks before the surgery, after my last attack and a CT scan, I was told I had fecal stasis (basically constipation). The days leading up to the surgery were awful—lots of nausea, barely eating, and still struggling to go to the bathroom. I had the surgery, and I was told everything went well and that I

Collected: 4/23/2026n=1Extraction: high
User reportabdominal_painmild

Reddit r/loseit — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: medium
User reportconstipationmoderate

Reddit r/loseit — Musely Age Well Pill

Hi All, I’ve been on the Musely Age Well Pill (750 mg Metformin and some other stuff) for about six weeks. When I began, I had lost about 10 lbs. Since I started the new medication, I have lost an additional 13 lbs. It definitely helps me with weight loss. However, the constipation is BAD. I usually tend towards getting diarrhea WAY more, so it’s been hard to deal with this. I’ve been taking stool softeners and a small dose of an herbal clean out daily, and my stomach still feels weird a lot o

Collected: 4/23/2026n=1Extraction: high
User reportvomitingmoderate

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Collected: 4/23/2026Dose: mediumn=1Extraction: high
User reportacid_refluxmoderate

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Collected: 4/23/2026Dose: mediumn=1Extraction: high
User reportdiarrheamild

Reddit r/Zepbound — Success on 2.5, struggling HARD on 5mg… stay or drop back down?

Hello all! Long post incoming… I’m struggling with side effects and I’m hoping to get some advice from others on what you would do in my situation. Background info- I’ve been on Zepbound since March 3rd, started on 2.5mg. My first dose was a doozy with sulfur burps and diarrhea but other than that it was smooth sailing and I lost about 13lbs in those 4 weeks on 2.5. I decided to move up to 5mg which is where the problems started for me. 24 hrs after my first dose the sulfur burps came back

Collected: 4/23/2026Dose: lown=1Extraction: high
User reportabdominal_painmoderate

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Collected: 4/23/2026Extraction: medium
User reportgallstones

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Collected: 4/23/2026Extraction: medium
User reportacid_reflux

Reddit r/Zepbound — Tacos are the word thing on the planet.

I was gonna post this on r/gallbladder but I’m still in denial mine needs to get removed, so I’m posting this here. Slowly overtime I haven’t been able to enjoy tacos because of my stomach problems. My mom made tacos for dinner, I was hungry and we really don’t have much to eat right now.. it can’t be so bad right? RIGHT?! Oh lord I was so wrong. I’m upstairs in my room and I’m like, okay feels kinda weird but I’ll power though..(I JUST GOT INTO COSPLAY) I take some medicine(tums and zofran) a

Collected: 4/23/2026Extraction: medium
User reportpancreatitissevere

Reddit r/Zepbound — Just had surgery, any tips?

I just got home from the hospital today from gallbladder surgery and emergency escaped gallstone surgery (I had a 3cm gallstone ripping apart my pancreas), my mom and grandma watched him while I was in the hospital. He is a super clingy baby because he's been teething. He weighs about 20lbs and has been killing my abdomen. Does anyone have any tips on how to lift and take care of him and how to not suffer so much from the mom guilt of occasionally having to let him just cry for a second to regai

Collected: 4/23/2026n=1Extraction: medium
User reportgallstonessevere

Reddit r/Zepbound — Just had surgery, any tips?

I just got home from the hospital today from gallbladder surgery and emergency escaped gallstone surgery (I had a 3cm gallstone ripping apart my pancreas), my mom and grandma watched him while I was in the hospital. He is a super clingy baby because he's been teething. He weighs about 20lbs and has been killing my abdomen. Does anyone have any tips on how to lift and take care of him and how to not suffer so much from the mom guilt of occasionally having to let him just cry for a second to regai

Collected: 4/23/2026n=1Extraction: medium
User reportabdominal_pain

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportconstipation

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportdiarrhea

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportnausea

Reddit r/Zepbound — Surgery on the 28th

I have a laparoscopic hysterectomy due to chronic painful periods that we haven’t been able to get under control. But while they are in there they will look for endometrial lesions! At the same time though, I will be having a general surgeon remove my hyperkinetic gallbladder as that has been causing a lot of upper right abdominal pain and nausea. I don’t know if they are related, but the pain gets worse when I ovulate so I think so. The thing is, I don’t want to wake up from this surgery at a

Collected: 4/23/2026Extraction: low
User reportnausea

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Sun, 19 Apr 2026 23:00:13 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

Collected: 4/22/2026Extraction: medium
Regulatory datadizziness

WHO/Nature — Pharmacovigilance analysis of neurological adverse events associated with GLP-1

Pharmacovigilance analysis of neurological adverse events associated with GLP-1 receptor agonists based on the FDA Adverse Event Reporting System - Nature Source: Nature Published: Sat, 24 May 2025 07:00:00 GMT Pharmacovigilance analysis of neurological adverse events associated with GLP-1 receptor agonists based on the FDA Adverse Event Reporting System  Nature

Collected: 4/22/2026Extraction: low
News source

India News — Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Los

Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Loss With Mounjaro - Outlook Luxe Published: Sat, 18 Apr 2026 07:30:00 GMT Forget Bridezillas, Meet The Indian Injection Bride Fast-Tracking Her Weight Loss With Mounjaro  Outlook Luxe

Collected: 4/22/2026Extraction: low
News sourceweight_regain

Ars Technica — There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests - A

There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests - Ars Technica Source: Ars Technica Published: Tue, 25 Nov 2025 08:00:00 GMT There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests  Ars Technica

Collected: 4/22/2026Extraction: low
News sourceweight_regain

McGill University — Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound - McGill Universit

Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound - McGill University Source: McGill University Published: Fri, 01 Aug 2025 07:00:00 GMT Don’t Play Yo-Yo with Your Weight: The ‘Post-Ozempic’ Rebound  McGill University

Collected: 4/22/2026Extraction: medium
News sourceemotional_blunting

MedPage Today — GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedP

GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedPage Today Source: MedPage Today Published: Tue, 21 Apr 2026 19:36:03 GMT GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk  MedPage Today

Collected: 4/22/2026Extraction: low
News sourcemuscle_loss

MedPage Today — GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedP

GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk - MedPage Today Source: MedPage Today Published: Tue, 21 Apr 2026 19:36:03 GMT GLP-1s and Muscle Loss; 'Ozempic Personality'; Acromegaly and Cancer Risk  MedPage Today

Collected: 4/22/2026Extraction: low
News sourcemuscle_lossmoderate

Medical Xpress — Weight loss leads to notable muscle loss, study finds - Medical Xpress

Weight loss leads to notable muscle loss, study finds - Medical Xpress Source: Medical Xpress Published: Fri, 17 Apr 2026 18:40:04 GMT Weight loss leads to notable muscle loss, study finds  Medical Xpress

Collected: 4/22/2026Extraction: low
News sourcemuscle_loss

EMJ — Tirzepatide linked to more lean mass loss than semaglutide - EMJ

Tirzepatide linked to more lean mass loss than semaglutide - EMJ Source: EMJ Published: Fri, 17 Apr 2026 11:17:54 GMT Tirzepatide linked to more lean mass loss than semaglutide  EMJ

Collected: 4/22/2026Extraction: medium
News sourcemuscle_loss

EMJ — Tirzepatide linked to more lean mass loss than semaglutide - EMJ

Tirzepatide linked to more lean mass loss than semaglutide - EMJ Source: EMJ Published: Fri, 17 Apr 2026 11:17:54 GMT Tirzepatide linked to more lean mass loss than semaglutide  EMJ

Collected: 4/22/2026Extraction: medium
User reportmuscle_loss

Reddit r/diabetes_t2 — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Collected: 4/22/2026Dose: lowExtraction: medium
User reportmuscle_lossmoderate

Reddit r/diabetes_t2 — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

Collected: 4/22/2026n=1Extraction: high
User reporthair_loss

Reddit r/diabetes — Nothing i do helps

Tldr nothing I've tried helps with my scalp and I'm really struggling with hair loss and breakage I've had eczema, mild and mostly managed without meds for most of my life. Then a couple years ago my skin and scalp flipped out. Weeping broken skin at the groin, behind the ears and my scalp was inflamed, red painful and itchy. Got to a Dermatologist, trying different tropicals, even tried biologics (a couple because at first they thought it was psoriasis) nothing really made a big difference.

Collected: 4/22/2026Extraction: low
User reportmuscle_loss

Reddit r/PCOS — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Collected: 4/22/2026Dose: lowExtraction: medium
User reportmuscle_lossmoderate

Reddit r/PCOS — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

Collected: 4/22/2026n=1Extraction: high
User reporthair_loss

Reddit r/compoundedtirzepatide — Nothing i do helps

Tldr nothing I've tried helps with my scalp and I'm really struggling with hair loss and breakage I've had eczema, mild and mostly managed without meds for most of my life. Then a couple years ago my skin and scalp flipped out. Weeping broken skin at the groin, behind the ears and my scalp was inflamed, red painful and itchy. Got to a Dermatologist, trying different tropicals, even tried biologics (a couple because at first they thought it was psoriasis) nothing really made a big difference.

Collected: 4/22/2026Extraction: low
User reportmuscle_loss

Reddit r/PeptideSource — Anyone start tirz at age 75+.

My grandma is starting at a microdose for her inflammation and arthritis on her knees and hands. I'm worried about muscle loss. The microdose would be 1mg

Collected: 4/22/2026Dose: lowExtraction: medium
User reportmuscle_lossmoderate

Reddit r/PeptideSource — To What Extent?

Tw: Weight, medical, self sabotage(?) I’m 17 year old girl and a year ago I was 180lbs and now I’m 120lbs. I made this happen through getting a job to pay for a Wegovy prescription my mom approved of. I’ve lost significant muscle, I can feel and see it on my body. And if I lose 10 more pounds I’ll be underweight. (Not my goal. I’m trying to maintain and gain muscle.) A year ago I thought, “people would like me more if I got skinny, it would change so many things.” Yes, but not in the way I exp

Collected: 4/22/2026n=1Extraction: high
Clinical studypancreatitis

medRxiv — GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic

Preprint: GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic review and meta-analysis Authors: Hume, S.; Bakker, L.; Caganek, T.; Rooprai, A. Date: 2026-03-23 Category: endocrinology Abstract: BackgroundThere are concerns that glucagon-like peptide-1 receptor agonists (GLP1s) increase the risk of acute pancreatitis. MethodsWe searched Medline and clinicaltrials.gov in March 2026 for placebo-controlled randomized trials of semaglutide and tirzepatide reporting the i

Collected: 4/21/2026n=40274Extraction: high
Clinical studypancreatitis

medRxiv — GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic

Preprint: GLP-1 receptor agonists and the risk of acute pancreatitis: a living systematic review and meta-analysis Authors: Hume, S.; Bakker, L.; Caganek, T.; Rooprai, A. Date: 2026-03-23 Category: endocrinology Abstract: BackgroundThere are concerns that glucagon-like peptide-1 receptor agonists (GLP1s) increase the risk of acute pancreatitis. MethodsWe searched Medline and clinicaltrials.gov in March 2026 for placebo-controlled randomized trials of semaglutide and tirzepatide reporting the i

Collected: 4/21/2026n=40274Extraction: high
Regulatory data

WHO/CBS News — FDA warns Novo Nordisk over unreported potential Ozempic side effects - CBS News

FDA warns Novo Nordisk over unreported potential Ozempic side effects - CBS News Source: CBS News Published: Tue, 10 Mar 2026 07:00:00 GMT FDA warns Novo Nordisk over unreported potential Ozempic side effects  CBS News

Collected: 4/21/2026Extraction: low
News sourcepancreatitis

India News — Centre increases monitoring of weight-loss drugs, flags safety concerns - Busine

Centre increases monitoring of weight-loss drugs, flags safety concerns - Business Standard Published: Sat, 04 Apr 2026 07:00:00 GMT Centre increases monitoring of weight-loss drugs, flags safety concerns  Business Standard

Collected: 4/21/2026Extraction: low
News sourcenausea

India News — Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss dr

Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss drugs - The News Mill Published: Mon, 20 Apr 2026 11:43:47 GMT Indian Pharmacopoeia Commission monitors adverse events linked to weight-loss drugs  The News Mill

Collected: 4/21/2026Extraction: low
User reportvomitingmild

Reddit r/diabetes — How far should I push myself.

This is more of a cardio question than specifically a running question but thought it would be a good place to ask. How do I know when to stop running? I'm an intermediate weight lifter that started hitting cardio related walls like consitent nausea. What is the ideal way to push your cardio I assume throwing up every time is not ideal. Do i just stop when it feels like a heart attack, tight chest can barely breathe or should I stop even earlier.

Collected: 4/21/2026Extraction: medium
User reportnauseamild

Reddit r/diabetes — How far should I push myself.

This is more of a cardio question than specifically a running question but thought it would be a good place to ask. How do I know when to stop running? I'm an intermediate weight lifter that started hitting cardio related walls like consitent nausea. What is the ideal way to push your cardio I assume throwing up every time is not ideal. Do i just stop when it feels like a heart attack, tight chest can barely breathe or should I stop even earlier.

Collected: 4/21/2026Extraction: high
Clinical studyabdominal_pain

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Collected: 4/21/2026Extraction: low
Clinical studynausea

Cochrane/Cochrane Library — Semaglutide for adults living with obesity - Bracchiglione, J - 2025 - Cochrane

Semaglutide for adults living with obesity - Bracchiglione, J - 2025 - Cochrane Library Source: Cochrane Library Published: Thu, 30 Oct 2025 07:00:00 GMT Semaglutide for adults living with obesity - Bracchiglione, J - 2025  Cochrane Library

Collected: 4/20/2026Extraction: low
User reportdiarrhea

Reddit r/loseit — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Collected: 4/20/2026Extraction: high
User reportacid_refluxmoderate

Reddit r/loseit — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Collected: 4/20/2026Extraction: high
User reportacid_reflux

Reddit r/loseit — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Collected: 4/20/2026Extraction: medium
User reportreduced_appetite

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: low
User reportacid_refluxmoderate

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: low
User reportvomiting

Reddit r/loseit — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: low
User reportdizziness

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Collected: 4/20/2026Extraction: low
User reportheadache

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Collected: 4/20/2026Extraction: low
User reportacid_refluxsevere

Reddit r/Ozempic — Eyelid twitching, Eye muscle pain and pressure, Eyes can't focus and light sensi

Hi. I'm F(26). For context I have GERD/Gastritis and Asthma as well as undiagnosed sinusitis (since I haven't visited an ENT ever) since I was a child. So, March 17th, my symptoms started when I hard severe attack of GERD and apparently also high level UTI (though I don't have sever symptoms only muscle aches and sick feeling). I battled for a month and finally went into a GI doctor and she also treated my UTI in about 2 weeks. She asked for a urine culture, prescribed me antibiotics first is ce

Collected: 4/20/2026Extraction: low
User reportdiarrheamoderate

Reddit r/Ozempic — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Collected: 4/20/2026Extraction: low
User reportacid_refluxmoderate

Reddit r/Ozempic — Hives + GERD post-treatment

Hi everyone. My husband (31M, PMBCL) has had a host of issues post-chemo and radiation. We’re still waiting for his PET scan to see results of treatment end of May. He’s been itching on and off, and any scratching of the skin results in raised marks/hives. He also has terrible acid reflux and loose bowels. Other than that, some breathlessness upon exertion and a few small boils on his skin that could also be ingrown hairs. We’ve spoken to his team about a few of these issues and they don’t s

Collected: 4/20/2026Extraction: low
User reportacid_reflux

Reddit r/Ozempic — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Collected: 4/20/2026Extraction: medium
User reportnausea

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: medium
User reportreduced_appetite

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: medium
User reportacid_refluxsevere

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: high
User reportvomiting

Reddit r/Ozempic — How to get rid of acid in throat after throwing up!

Whenever I throw up, I feel the acid in my throat and chest linger for the entire day. After that I cant even taste my food, or eat and feel sick the entire day. I’m now going into 3 trimester and my acid reflux is BAD. So it’s even worse now. Is there anything I can do to get rid of the acid feeling in my throat and chest after throwing up?

Collected: 4/20/2026Extraction: high
User reportacid_reflux

Reddit r/intermittentfasting — Has anyone tried Mounjaro with GERD?

Given the slow motility I understand it may make my GERD symptoms worse. But my doctor has said my nighttime reflux symptoms, which really affect my sleep, may improve if I lose weight - so I am tempted to try it. Any experiences?

Collected: 4/20/2026Extraction: medium
User reportnausea

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Wed, 15 Apr 2026 23:00:18 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

Collected: 4/19/2026Extraction: medium
Regulatory dataemotional_blunting

EMA/EudraVigilance — Weight-loss jabs investigated for suicide risk - BBC

Weight-loss jabs investigated for suicide risk - BBC Source: BBC Published: Sun, 09 Jul 2023 07:00:00 GMT Weight-loss jabs investigated for suicide risk  BBC

Collected: 4/19/2026Extraction: low
Regulatory datapancreatitis

MHRA/genomicsengland.co.uk — The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of

The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of acute pancreatitis - genomicsengland.co.uk Source: genomicsengland.co.uk Published: Thu, 26 Jun 2025 07:00:00 GMT The Yellow Card Biobank starts investigating GLP-1 medicines and genetic risk of acute pancreatitis  genomicsengland.co.uk

Collected: 4/19/2026Extraction: low
Regulatory datapancreatitissevere

MHRA/The BMJ — GLP-1 drugs: New warning after rise in reported deaths from pancreatitis - The B

GLP-1 drugs: New warning after rise in reported deaths from pancreatitis - The BMJ Source: The BMJ Published: Fri, 30 Jan 2026 08:00:00 GMT GLP-1 drugs: New warning after rise in reported deaths from pancreatitis  The BMJ

Collected: 4/19/2026Extraction: medium
News sourceweight_regain

Cureus — Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation

Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists and Other Anti-obesity Drugs - Cureus Source: Cureus Published: Sun, 19 Oct 2025 07:00:00 GMT Rebound or Retention: A Meta-Analysis of Weight Regain After the Discontinuation of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists and Other Anti-obesity Drugs  Cureus

Collected: 4/19/2026Extraction: low
News sourcenausea

Scientific American — Experimental GLP-3 weight-loss drug retatrutide shows promising results in clini

Experimental GLP-3 weight-loss drug retatrutide shows promising results in clinical trial - Scientific American Source: Scientific American Published: Thu, 19 Mar 2026 07:00:00 GMT Experimental GLP-3 weight-loss drug retatrutide shows promising results in clinical trial  Scientific American

Collected: 4/19/2026Extraction: low
Regulatory dataproduct_use_in_unapproved_indication3%

FDA FAERS — semaglutide — PRODUCT USE IN UNAPPROVED INDICATION

FDA adverse event reports for semaglutide: PRODUCT USE IN UNAPPROVED INDICATION reported 3039 times out of 99460 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/19/2026n=99460Extraction: high
User reportdiarrheamoderate

Reddit r/PeptideSource — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: low
User reportconstipation

Reddit r/PeptideSource — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: low
User reportconstipation

Reddit r/PeptideSource — Am I crazy or is there something wrong with me? 20F

Hi everyone! About me: I'm a white 20 female and I'm a 192 pounds. I don't smoke, drink, and or use any drugs. The only existing medical issue that I have is diagnosed PCOS. I do have a constant history with constipation. As for medications, I'm on Concerta (36mg) for ADHD. Semaglutide injections once a week (15 units, been on it for a year and have lost over 70 pounds with no problems). Last, Zofran (8mg) as needed. I work out and eat clean as well. Family history: On my father's side; grandm

Collected: 4/19/2026Dose: mediumn=1Extraction: high
User reportdiarrheamoderate

Reddit r/semaglutide — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: high
User reportconstipation

Reddit r/semaglutide — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: high
User reportgallstones

Reddit r/semaglutide — Need advice on whether this gallbladder actually needs to come out. Ultrasound p

**5’5”, 30 years old, 185 pounds, don’t smoke, 50mg vyvanse and 10mg xyzal a day. Currently use Zyns, vaped for about a year. I have PCOS, mild insulin resistance, Chronic Spontaneous Urticaria, IBS-C, and got a 5mm colon adenoma removed earlier this month.** I recently had an abdominal ultrasound that showed a gallbladder polyp, with the radiology report stating “multiple polyps, one polyp up to 6 mm.” My gallbladder wall measured 1.66 mm (normal), common bile duct about 5.8 mm (upper end of no

Collected: 4/19/2026n=1Extraction: medium
User reportgallstones

Reddit r/WegovyWeightLoss — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Collected: 4/19/2026Extraction: medium
User reportabdominal_painsevere

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Collected: 4/19/2026Extraction: low
User reportacid_refluxmoderate

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Collected: 4/19/2026Extraction: low
User reportgallstonessevere

Reddit r/WegovyWeightLoss — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Collected: 4/19/2026Extraction: low
User reportgallstones

Reddit r/WegovyWeightLoss — Why are doctors so hesitant to remove gallbladders?

That’s been my observation, anyway. I know a few people, including myself, that have confirmed stones + a ton of symptoms due to it but doctors refuse to do surgery. Why is that?

Collected: 4/19/2026Extraction: medium
User reportkidney_issuesmoderate

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: low
User reportabdominal_painsevere

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: medium
User reportkidney_issuessevere

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: medium
User reportabdominal_painsevere

Reddit r/WegovyWeightLoss — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: high
User reportdiarrheamoderate

Reddit r/loseit — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: low
User reportconstipation

Reddit r/loseit — it’s liquid

Ok autism alone isn’t enough I need to switch between constipation and LIQUID DIARRHEA.

Collected: 4/19/2026Extraction: low
User reportgallstonesmoderate

Reddit r/Zepbound — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Collected: 4/19/2026n=1Extraction: medium
User reportinjection_site_reactionsevere

Reddit r/Zepbound — First, I have been to 2 doctors now. I have a dermatologist appointment coming u

The 1st time I had one on each breast, almost identical. The 2nd time I had 1 on each side also just above ass cheeks, on lower back. Almost identical on each side. 3rd time, one on each shoulder blade also almost identical placement on each side. I now have huge scars from all of them. 😢 The second incident, I happened to be in the hospital for my gallbladder. So, the attending doctor sent a dermatologist and she did a biopsy. Results came back..... nothing. Nothing came back abnormal. She h

Collected: 4/19/2026n=1Extraction: high
User reportacid_refluxmild

Reddit r/Zepbound — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Collected: 4/19/2026Extraction: low
User reportgallstonesmoderate

Reddit r/Zepbound — what feels like an attack 2 years after removal

hi gang, I got my gallbladder removed 2 years ago (march 24’). i started getting horrible attacks nov ‘24 and since then I’ve been dealing with annoying GERD and heartburn issues on the daily. anyway today I went in on some pizza, something I have done since my removal, and 3 hours later and the area where my gallbladder used to be is pulsing painfully. It’s gotta be the pizza right? I’m so used to heartburn but not pain like this. I’d love some reassurance lol (also no history of stones, got

Collected: 4/19/2026Extraction: low
User reportgallstones

Reddit r/Zepbound — Why are doctors so hesitant to remove gallbladders?

That’s been my observation, anyway. I know a few people, including myself, that have confirmed stones + a ton of symptoms due to it but doctors refuse to do surgery. Why is that?

Collected: 4/19/2026Extraction: medium
User reportkidney_issuesmoderate

Reddit r/Zepbound — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: medium
User reportabdominal_painsevere

Reddit r/Zepbound — Spiked AST and ALT - new here, what does it mean?

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: high
User reportkidney_issuesmoderate

Reddit r/Zepbound — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: medium
User reportabdominal_painsevere

Reddit r/Zepbound — Spiked AST and ALT - new here and I'm scared

A few days ago I (41F) was writhing on the floor at work in terrible pain. Went to ER. My AST and ALT went from normal to 400 to 2000 in less than 12 hrs. 3 days later numbers are coming down (AST 500 and ALT 1300). Hospital sent me home with orders to follow-up w gi later next week. Pain isn't zero but it's bearable. I'm spiraling and unsure what to do. Alkaline phosphatase (sp?) and ammonia are high. Hepatitis is negative. I eat pretty healthy, veggies at every meal. Exercise 3-4x/week. No di

Collected: 4/19/2026n=1Extraction: high
User reportgeneral_side_effectssevere

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "No need for details. I experienced the same awful side effects as many of the posters. So I quit the drug and went on a low-carb diet (little or no grains, starches, or sugar) and started walking 20 minutes every day as fast as I could. Lost 40 lbs. A1C went from 8.0 to 5.5. Never felt better. But I am still diabetic, meaning I cannot go back to my old ways. If I can do it, you can do it. Oh, and the money I am saving!"

Collected: 4/18/2026Extraction: low
Regulatory data3%

FDA FAERS — dulaglutide — EXTRA DOSE ADMINISTERED

FDA adverse event reports for dulaglutide: EXTRA DOSE ADMINISTERED reported 3106 times out of 101618 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/18/2026Dose: highn=101618Extraction: high
User reportabdominal_painsevere

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportdiarrheamoderate

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportvomitingsevere

Reddit r/semaglutide — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportdiarrheamoderate

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportvomitingmoderate

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportnauseamild

Reddit r/semaglutide — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportconstipationmoderate

Reddit r/semaglutide — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Collected: 4/18/2026n=1Extraction: high
User reportnauseamoderate

Reddit r/semaglutide — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Collected: 4/18/2026n=1Extraction: high
User reportreduced_appetite

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportdiarrhea

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportvomiting

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportnausea

Reddit r/semaglutide — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportweight_regain

Reddit r/WegovyWeightLoss — Restarting Zepbound after 3 weeks off, doctor said it was okay to continue on th

TW: Pregnancy Loss Hi everyone! My journey has been a bit weird so far. I started zepbound the first Friday of February. I lost about 10 pounds on the 2.5 and 8 pounds on the 5mg. I ended up ovulating and wound up pregnant with my positive happening on March 24th. I stopped my zepbound accordingly. Unfortunately, this ended in a miscarriage. I asked the NP if it was okay to continue on the 5mg and she agreed. I had missed 3 doses. I'm just wondering if anyone has had a similar experience of

Collected: 4/18/2026Dose: mediumn=1Extraction: medium
User reportabdominal_painmoderate

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportdiarrheamild

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportvomitingmoderate

Reddit r/loseit — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: medium
User reportdiarrheamoderate

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportvomitingmoderate

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportnauseamild

Reddit r/loseit — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportreduced_appetite

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportdiarrhea

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportvomiting

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportnausea

Reddit r/loseit — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User report

Reddit r/Zepbound — Restarting Zepbound after 3 weeks off, doctor said it was okay to continue on th

TW: Pregnancy Loss Hi everyone! My journey has been a bit weird so far. I started zepbound the first Friday of February. I lost about 10 pounds on the 2.5 and 8 pounds on the 5mg. I ended up ovulating and wound up pregnant with my positive happening on March 24th. I stopped my zepbound accordingly. Unfortunately, this ended in a miscarriage. I asked the NP if it was okay to continue on the 5mg and she agreed. I had missed 3 doses. I'm just wondering if anyone has had a similar experience of

Collected: 4/18/2026Dose: mediumn=1Extraction: high
User reportabdominal_painsevere

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: high
User reportdiarrheamild

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: high
User reportvomitingsevere

Reddit r/Ozempic — Nausea, vomiting and bowel issues

My child is a 16 year old female. She is 5’ tall, around 173lbs. She does not smoke. She has had pain in her right side from just under her ribs down to just above her pelvic bone that radiates towards the navel area. It cramps badly, almost like menstrual cramps, but worse. It’s a constant dull ache with bouts of stabbing pains. This started 11/6/2025 and is still ongoing. I have a long list of everything that has been going on since Nov 2025. We are working with a GI dr right now, but I wond

Collected: 4/18/2026n=1Extraction: high
User reportdiarrheamoderate

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportvomitingmoderate

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportnauseamild

Reddit r/Ozempic — Sudden Nausea

I've been on Mounjaro for about 18 months, steady on 10mg for roughly the last year. Had some minor nausea in the first few months, a bit extra gassy, nothing major. The occasional Zofran dealt with it, but rare enough that the prescription expired before I needed my first refill. About two months ago, my son tested positive for flu. We all got two weeks of Tamiflu to ward off catching it from him. (Successful as far as that went.) Toward the end of that period, I had a night where I had severa

Collected: 4/18/2026Dose: highExtraction: high
User reportconstipationmoderate

Reddit r/Ozempic — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Collected: 4/18/2026Extraction: high
User reportnauseamoderate

Reddit r/Ozempic — Do I need to go back to hospital?

I was in hospital at 5w6d and they gave me 1L of fluids and some Ondansetron. I'm taking 8mg Ondansetron every 7.5hrs but I'm still so nauseous, the only thing that helps a little is to push past the empty stomach feeling and then I get a tiny bit of relief. Not eating or drinking anything at all is the only thing that's helping. I haven't had a proper bowel movement in over a week. The stool softener powder makes me gag and makes the nausea worse. Fibre gummies didn't help. Is this go back to h

Collected: 4/18/2026Extraction: high
User reportdiarrhea

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportvomiting

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
User reportnausea

Reddit r/Ozempic — Participate in a Paid Research Study To Understand Your Experience with GLP-1 Me

Are you an adult in the US currently using an FDA-approved **GLP-1** medication for weight management? You may be eligible to participate in a research study. Bridge Access Solutions (BAS) is conducting a research study with individuals currently prescribed a GLP-1 medication to gain insight into real-world participant experiences and to identify unmet needs. **What’s Involved**: Completion of an electronic, 8–10-minute daily diary over a period of 6 weeks. You will be asked questions about yo

Collected: 4/18/2026Extraction: high
Clinical studynausea

PubMed — 10.1016/S2213-8587(24)00182-7. Epub 2024 Jul 29.

Lancet Diabetes Endocrinol. 2024 Sep;12(9):631-642. doi: 10.1016/S2213-8587(24)00182-7. Epub 2024 Jul 29. Efficacy and safety of once-weekly semaglutide 2·4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial. McGowan BM(1), Bruun JM(2), Capehorn M(3), Pedersen SD(4), Pietiläinen KH(5), Muniraju HAK(6), Quiroga M(7), Varbo A(7), Lau DCW(8); STEP 10 Study Group. Author information: (1)Department of Di

Collected: 4/18/2026Dose: highExtraction: low
User reportnausea

Twitter/X — An over-the-counter ginger supplement could help reduce nausea associated with t

Tweet/X post: An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double-blind randomized pilot trial of people with obesity and/or type 2 diabete - x.com Published: Wed, 15 Apr 2026 23:00:18 GMT An over-the-counter ginger supplement could help reduce nausea associated with the use of GLP-1 agonists, new research suggests. The findings come from a placebo-controlled, double

Collected: 4/17/2026Extraction: medium
User reporthair_loss

Twitter/X — 'I was told about the hair loss but I never expected this': The brutal Mounjaro

Tweet/X post: 'I was told about the hair loss but I never expected this': The brutal Mounjaro side-effect that only affects women - and doctors aren't warning them about it - x.com Published: Sat, 29 Nov 2025 08:00:00 GMT 'I was told about the hair loss but I never expected this': The brutal Mounjaro side-effect that only affects women - and doctors aren't warning them about it  x.com

Collected: 4/17/2026Extraction: high
News sourceweight_regain

Medical Xpress — Tirzepatide's benefits fade for most: Weight and health markers rebound after wi

Tirzepatide's benefits fade for most: Weight and health markers rebound after withdrawal, study finds - Medical Xpress Source: Medical Xpress Published: Fri, 28 Nov 2025 08:00:00 GMT Tirzepatide's benefits fade for most: Weight and health markers rebound after withdrawal, study finds  Medical Xpress

Collected: 4/17/2026Extraction: high
News sourceweight_regain

CLGF — New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How F

New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How Fast - CLGF Source: CLGF Published: Wed, 25 Feb 2026 08:00:00 GMT New Data Warn: Stopping Ozempic Often Brings Back Lost Weight, Study Shows How Fast  CLGF

Collected: 4/17/2026Extraction: medium
News sourceweight_regain

MedCentral — Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps - Me

Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps - MedCentral Source: MedCentral Published: Wed, 31 Dec 2025 08:00:00 GMT Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical Research Gaps  MedCentral

Collected: 4/17/2026Extraction: low
News sourceweight_regain

SciTechDaily — Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks

Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks, Study Warns - SciTechDaily Source: SciTechDaily Published: Mon, 12 Jan 2026 08:00:00 GMT Stopping GLP-1 Weight Loss Drugs Leads to Fast Rebound in Weight and Heart Risks, Study Warns  SciTechDaily

Collected: 4/17/2026Extraction: medium
News sourceweight_regain

The BMJ — After the Injection: GLP-1 Discontinuation and Weight Regain - The BMJ

After the Injection: GLP-1 Discontinuation and Weight Regain - The BMJ Source: The BMJ Published: Wed, 07 Jan 2026 08:00:00 GMT After the Injection: GLP-1 Discontinuation and Weight Regain  The BMJ

Collected: 4/17/2026Extraction: low
News sourcemuscle_loss

University of Utah Health — New Study Raises Questions About How Ozempic Affects Muscle Size and Strength -

New Study Raises Questions About How Ozempic Affects Muscle Size and Strength - University of Utah Health Source: University of Utah Health Published: Tue, 05 Aug 2025 07:00:00 GMT New Study Raises Questions About How Ozempic Affects Muscle Size and Strength  University of Utah Health

Collected: 4/17/2026Extraction: medium
News sourceemotional_blunting

The Guardian — Is a new weight-loss drug making people fall out of love? - The Guardian

Is a new weight-loss drug making people fall out of love? - The Guardian Source: The Guardian Published: Mon, 06 Apr 2026 07:00:00 GMT Is a new weight-loss drug making people fall out of love?  The Guardian

Collected: 4/17/2026Extraction: low
News sourceemotional_blunting

KTLA — ‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs -

‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs - KTLA Source: KTLA Published: Thu, 16 Apr 2026 20:57:01 GMT ‘Ozempic personality’: Some users reporting emotional blunting on GLP-1 drugs  KTLA

Collected: 4/17/2026Extraction: medium
News sourceemotional_blunting

The Washington Post — What is ‘Ozempic personality,’ and why does it make life feel ‘meh’? - The Washi

What is ‘Ozempic personality,’ and why does it make life feel ‘meh’? - The Washington Post Source: The Washington Post Published: Thu, 16 Apr 2026 16:00:00 GMT What is ‘Ozempic personality,’ and why does it make life feel ‘meh’?  The Washington Post

Collected: 4/17/2026Extraction: medium
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Do you guys get these itchy spots ?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Itchy injection sites at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Itchy injection lumps at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
User reportfatigue

Reddit r/PeptideSource — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Collected: 4/17/2026Extraction: low
User reporthair_loss

Reddit r/PeptideSource — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Collected: 4/17/2026Extraction: low
User reportfatiguemoderate

Reddit r/semaglutide — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Collected: 4/17/2026n=1Extraction: high
User reporthair_lossmoderate

Reddit r/semaglutide — Testosterone level 209

Hi I got told about a week ago I have pcos and my testosterone is very high I am 24 weigh 211 pounds my symptoms are I have hair loss and breakage bad , inconsistent period and was spotting like every day in-between my cycles, and excessive leg and bikini line hair, acne and cannot lose weight, very low energy And fatigue can sleep 12 hours and still be tired . My testosterone is at 209 and my estrogen is 65.. I have looked into this and found my testosterone is extremely high even for pcos, doe

Collected: 4/17/2026n=1Extraction: high
User reportinjection_site_reactionmild

Reddit r/WegovyWeightLoss — Do you guys get these itchy spots ?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
User reportinjection_site_reactionmild

Reddit r/WegovyWeightLoss — Itchy injection sites at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
User reportinjection_site_reactionmild

Reddit r/WegovyWeightLoss — Itchy injection lumps at 7.5mg?

I recently started tirzepatide at 2.5 mg, then moved up to 5 mg, and now 7.5 mg. I had no issues at first, but at the higher dose I’m getting bumps or lumps under the skin after injections. Sometimes the area is a bit red and mildly itchy, but mostly normal. My last injection was 8 days ago and I still feel a lump on my thigh that sometimes itches. I also injected again and now I’m starting to feel a similar lump forming on the other thigh. How long do these injection-site reactions usually last

Collected: 4/17/2026Dose: highExtraction: high
Clinical studynausea

PubMed — Tirzepatide once weekly for the treatment of obesity in people with type 2

Lancet. 2023 Aug 19;402(10402):613-626. doi: 10.1016/S0140-6736(23)01200-X. Epub 2023 Jun 26. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. Garvey WT(1), Frias JP(2), Jastreboff AM(3), le Roux CW(4), Sattar N(5), Aizenberg D(6), Mao H(7), Zhang S(7), Ahmad NN(7), Bunck MC(7), Benabbad I(7), Zhang XM(7); SURMOUNT-2 investigators. Collaborators: Abalos FH, Manghi

Collected: 4/17/2026Extraction: low
User reportreduced_appetite

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Just took my third shot. I am 60 years old, female, 5'7'', and weigh 295. I lost 5 pounds by the 2nd shot. Maybe that's not terribly impressive, but I don't want to lose quickly. Here's what I think is an absolute miracle with Zepbound: NO HEAD HUNGER! For the first time (probably in my life), I don't think about food. I don't crave junk food, I get full very quickly and can only eat small amounts. I h

Collected: 4/16/2026n=1Extraction: high
User reportreduced_appetitemoderate

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportnauseamoderate

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I’ve been on Ozempic for 4 weeks. I am so glad that my doctor sat me down and told me what to expect. She also asked if I could handle it. She said that if you can make it through the 4th week, I promise it will get better. She was right. I was pretty sick the first two weeks. I learned that it had a lot to do with me trying to eat my normal intake of food. Once I started to catch a clue and make my portions smaller, I

Collected: 4/16/2026n=1Extraction: high
User reportdizzinessmoderate

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportheadachemoderate

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportconstipationmoderate

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportvomitingsevere

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportacid_refluxsevere

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 1 / 10 For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever f

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportfatiguemild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Collected: 4/16/2026n=1Extraction: high
User reportheadachemild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Collected: 4/16/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed

Collected: 4/16/2026n=1Extraction: high
User reportreduced_appetitemild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportdiarrhea

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportnausea

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportweight_regain

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "6 months. -65 pounds. Hypertension gone. Pre-Diabetes gone. Sleep apnea gone. Lower leg skin breakdown gone. Slow progress now. I must fight the return of old eating habits. Wegovy is not for wimps. But if you really want to lose weight, this is the way to go. This is like bariatric surgery in a small needle."

Collected: 4/16/2026n=1Extraction: medium
User reportdizzinessmild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 9 / 10 "Started taking this medication off label for weight loss only. I am not diabetic. Started on Aug 30, 2020. First 2 weeks I had some mild nausea, nothing terrible, and some mild dizziness. The past 2 weeks, I have had no symptoms. I definitely cannot eat what I used to, or you will feel sick. I am doing the weekly injection at 0.25 along with Weight Watchers, and in the past 26 days, I have lost 10.5 lbs :). My sweet tooth cravings are pretty much

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportnauseamild

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 9 / 10 "Started taking this medication off label for weight loss only. I am not diabetic. Started on Aug 30, 2020. First 2 weeks I had some mild nausea, nothing terrible, and some mild dizziness. The past 2 weeks, I have had no symptoms. I definitely cannot eat what I used to, or you will feel sick. I am doing the weekly injection at 0.25 along with Weight Watchers, and in the past 26 days, I have lost 10.5 lbs :). My sweet tooth cravings are pretty much

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportno_side_effects_reported

Drugs.com Review — semaglutide — General

Patient review for semaglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have been taking Wegovy for 1 week and 2 days. Only had the 0.25 dosage. I have had no side effects and I have lost 8 lbs. I am hoping as I increase the dosage I remain free of side effects and the weight continues to fall off. I will continue to leave feedback so people can see how it is working and hopefully it will help them make a decision. I almost didn't go through with the first injection beca

Collected: 4/16/2026Dose: lown=1Extraction: high
User reportfatigue

Reddit r/compoundedtirzepatide — started a new job and i’ve been calling in at least once a week.

i’m 18 from New Zealand and i’ve started a new job at a hardware store about a month ago, i recently graduated in november and now im doing 45 hours a week right on the spot which has been burning me out. i dont have a car so im having to take 2 busses and wake up at 5am before the sun comes up, and getting home at 7:30pm when the sun is down. i wake up everyday trying to push myself to get up but theres some days where i genuinely cant do it. i made the decision to talk to my boss since i cant

Collected: 4/16/2026Extraction: low
User reportdiarrhea

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Collected: 4/16/2026Extraction: low
User reportfatigue

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Collected: 4/16/2026Extraction: low
User reportabdominal_pain

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Collected: 4/16/2026Extraction: low
User reportheadache

Reddit r/compoundedtirzepatide — Chronically ill and struggling to develop a routine, wondering if anyone could h

Hi all, I made a post yesterday about stress management in the chronic illness sub, and i think one thing that will help me is developing a routine but the thing is, I feel way too overwhelmed to even know where to start (19f btw if that matters) Just a disclaimer I am not seeking a diagnosis from this sub! Please know I am seeing my pcp and an allergist! (They suspect endometriosis and MCAS due to my symptoms) My biggest symptoms are: Headaches, Abdominal pain, Fatigue, shortness of breath an

Collected: 4/16/2026Extraction: low
User reportfatiguemoderate

Reddit r/compoundedtirzepatide — I Didn’t Realize How Tired I Was Until I Slowed Down

Some days I’d wake up feeling heavy and call it laziness. I’d lie there, already behind on the day, already thinking about everything I wasn’t doing. By evening, that feeling turned into guilt. The fix, in my head, was always the same: more discipline, more effort, try harder tomorrow. A few days ago, I stopped pushing for once. I didn’t try to turn the day around or compensate for it later. I rested and left it at that. That’s when something clicked. The problem wasn’t laziness. I’d been

Collected: 4/16/2026Extraction: medium
User reportinjection_site_reactionmild

Twitter/X — “Ozempic itch” is all over social media but should you be worried? Some people u

Tweet/X post: “Ozempic itch” is all over social media but should you be worried? Some people using GLP-1 medications may experience mild injection-site itching or redness. According to Dr. Anne Peters, these reactions usually resolve within a few days. If itching spreads - x.com Published: Tue, 10 Mar 2026 07:00:00 GMT “Ozempic itch” is all over social media but should you be worried? Some people using GLP-1 medications may experience mild injection-site itching or redness. According to Dr. An

Collected: 4/15/2026Extraction: high
User reportnausea

Quora — Has anyone had any experiences with the diet drug saxenda? - Quora

Quora Q&A: Has anyone had any experiences with the diet drug saxenda? - Quora Published: Sat, 30 Apr 2016 07:00:00 GMT Has anyone had any experiences with the diet drug saxenda?  Quora

Collected: 4/15/2026Extraction: low
User reportreduced_appetite

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "Started Saxenda January 1, 2020 at 300.4 lbs. To date February 21, I am down 44 lbs. 1000 to 1200 calories per day and 10k to 12k average # of steps per day. Cravings are gone low appetite, and nausea if I try to eat too much. Few side effects now but same as everyone else at the beginning. By the end of my 2nd script, I may be down 60 lbs and would like to stop shots for a while but concerned about gai

Collected: 4/15/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "Started Saxenda January 1, 2020 at 300.4 lbs. To date February 21, I am down 44 lbs. 1000 to 1200 calories per day and 10k to 12k average # of steps per day. Cravings are gone low appetite, and nausea if I try to eat too much. Few side effects now but same as everyone else at the beginning. By the end of my 2nd script, I may be down 60 lbs and would like to stop shots for a while but concerned about gai

Collected: 4/15/2026n=1Extraction: high
User reportreduced_appetitemild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Collected: 4/15/2026Dose: lowExtraction: high
User reportvomitingsevere

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Collected: 4/15/2026Dose: highExtraction: high
User reportnauseasevere

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started Saxenda on Oct. 15, 2020 and have easily lost 20 pounds. I have remained on the initial dose of 0.6 because any higher dosage and I was horribly nauseous and vomiting. Most notable for anyone who enjoys cocktails and wine (not to excess) is that I have almost an aversion to this. Smaller meals, no need to snack, increased walking and I feel great. 10 more pounds to go and not in any hurry. Th

Collected: 4/15/2026Dose: highExtraction: high
User reportreduced_appetite

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I started using Saxenda on June 2. I am 43 years old and my starting weight was 87.8 kg. My height is 172 cm and I’m very athletic. For the past two years, my weight started to slowly escalate from 73 kg to 87.8 kg. I’m not sure if that is due to hypothyroidism or age, but in either case I wasn’t very happy because no matter how much I was working out or dieting, my weight would increase. My doctor rec

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportconstipationmoderate

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Collected: 4/15/2026n=1Extraction: high
User reportacid_refluxmild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Collected: 4/15/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Started October 19, 2020. First three months, side effects were nausea and acid reflux. At about 2 months in, constipation was bad. Started eating All-Bran every morning and taking 1 FloraLax daily, and the constipation went away in two weeks. Almost 4 months in, all side effects are gone, so my body got used to the drug. Started at 201 lb, BMI 34. Now 165 lb, BMI 29. I am 62 years old and thought I co

Collected: 4/15/2026n=1Extraction: high
User reportreduced_appetite

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I've been on Saxenda for seven days. My starting weight was 186.4, and today I'm 181, that's >5 lbs in one week! I have had very, very mild nausea for a few minutes after the first dose, unusual taste in my mouth, I'm incredibly thirsty and have a dry mouth. I have lost my appetite and only feel the need to eat around dinner time. At this point, I have a nutritious soup and a slice of brown sourdough. I

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportnauseamild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I've been on Saxenda for seven days. My starting weight was 186.4, and today I'm 181, that's >5 lbs in one week! I have had very, very mild nausea for a few minutes after the first dose, unusual taste in my mouth, I'm incredibly thirsty and have a dry mouth. I have lost my appetite and only feel the need to eat around dinner time. At this point, I have a nutritious soup and a slice of brown sourdough. I

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportnauseamild

Drugs.com Review — liraglutide — General

Patient review for liraglutide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I am currently in week 3. I have lost 14 pounds. The side effects have been minimal, and are a little stronger on a day that I increase dosage. The notable side effects are a light nausea when it is time to eat, or after a meal in which I have eaten more than I should. I am incredibly pleased with the results of this medication. I feel good, and my stamina for exercise has increased. My blood pressure

Collected: 4/15/2026n=1Extraction: high
User report

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Thank you Zepbound for showing me what being full was. It's a whole new feeling. I have more pep in my step. Four weeks in, over 20 pounds lost. Bring on the 2024 weight loss journey!! (2.5 dose, going up next shot)"

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportnauseamild

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have been on the 15 mg/0.5 mL for the last four months and on Mounjaro for a total of ten months starting with the 2.5 mg dosage. Well, I have to say I love it. I had a bit of nausea in the beginning but that’s it, never had it again. I have lost a total of 115 lbs. I don’t just eat whatever I want though, I have mainly been eating chicken, eggs, and turkey with things like cauliflower rice and once

Collected: 4/15/2026Dose: mediumn=1Extraction: high
User report

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "Just took my third shot. I am 60 years old, female, 5'7'', and weigh 295. I lost 5 pounds by the 2nd shot. Maybe that's not terribly impressive, but I don't want to lose quickly. Here's what I think is an absolute miracle with Zepbound: NO HEAD HUNGER! For the first time (probably in my life), I don't think about food. I don't crave junk food, I get full very quickly and can only eat small amounts. I h

Collected: 4/15/2026n=1Extraction: high
User reportconstipation

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "I have learned to manage side effects (constipation) with probiotics. This is the only thing that has allowed me to lose the weight I gained post-menopause. I was a size 22 and am now almost a size 10. My BMI went from 39 to just over 30, and I have about 25 more pounds to go. I lost 45 pounds currently. I am no longer taking medication for migraines, asthma, and chronic edema, and my BP medication has

Collected: 4/15/2026n=1Extraction: high
User reportabdominal_painmoderate

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportdiarrheamild

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportvomitingmoderate

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportnauseamoderate

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 8 / 10 For Weight Loss (Obesity/Overweight) "Started Zepbound 2 days ago. Ate normally the day of the first injection (2.5mg/0.5ml)... boy, did I make a mistake. I ate 3 meals, my last around 6 PM. That night I felt like a rock was in my stomach, and you could hear the sloshing of water and food as I moved in bed. I started dry heaving and gagging in my sleep. Woke up Tuesday morning feeling sicker than I did when I had morning sickness from pregn

Collected: 4/15/2026Dose: lown=1Extraction: high
User reportweight_regain

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 10 / 10 For Weight Loss (Obesity/Overweight) "315-pound man, 64 heavy drinker, quit all booze, gained weight. Began rowing machine daily, gained weight. Counted all calories, 2500/day, no loss. A1C not bad 7, went on Mounjaro lowest dose 2.5. Have lost 40 pounds (!) in two months, eat anything and everything just way less and no desire to snack between. Still losing a bit, but feel plateau, may ask for larger dose. A miracle, has changed my life m

Collected: 4/15/2026Dose: lown=1Extraction: medium
User reportinjection_site_reactionmild

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I am an African American female, 58 years old, 5’8” tall, weighed an unbelievable 270 lbs on 12/30/22. I asked my doctor if I could take this medication, and now here we are, 8 weeks later. I currently weigh 244.6 lbs. I lost 16 lbs in the first 3 weeks. I was extremely shocked and a little worried. My health is a constant concern, I suffer from chronic allergies, and frequently took steroid shots to ma

Collected: 4/15/2026n=1Extraction: high
User reportfatigue

Drugs.com Review — tirzepatide — General

Patient review for tirzepatide — Rating: 9 / 10 For Weight Loss (Obesity/Overweight) "I am an African American female, 58 years old, 5’8” tall, weighed an unbelievable 270 lbs on 12/30/22. I asked my doctor if I could take this medication, and now here we are, 8 weeks later. I currently weigh 244.6 lbs. I lost 16 lbs in the first 3 weeks. I was extremely shocked and a little worried. My health is a constant concern, I suffer from chronic allergies, and frequently took steroid shots to ma

Collected: 4/15/2026n=1Extraction: high
Regulatory datahair_loss

EMA/EudraVigilance — Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (

Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists for Weight Loss: A Scoping Review - Cureus Source: Cureus Published: Wed, 13 Aug 2025 07:00:00 GMT Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists for Weight Loss: A Scoping Review  Cureus

Collected: 4/15/2026Extraction: low
Clinical studymuscle_loss

ClinicalTrials.gov — Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Clinical trial: Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment NCT ID: NCT07226947 Status: RECRUITING Phase: NA Enrollment: 100 participants Conditions: Obesity, Body Composition Interventions: Smartwatch activity and body composition monitor, General guidance on recommended exercise Primary outcomes: Lean mass (kg) Secondary outcomes: Lean mass index (kg/m2); Appendicular lean mass index (kg/m2); Fat mass index (kg/m2); Fat mass (kg); Visceral adipose tissue (k

Collected: 4/15/2026n=100Extraction: medium
Clinical studymuscle_loss

ClinicalTrials.gov — Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Clinical trial: Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment NCT ID: NCT07226947 Status: RECRUITING Phase: NA Enrollment: 100 participants Conditions: Obesity, Body Composition Interventions: Smartwatch activity and body composition monitor, General guidance on recommended exercise Primary outcomes: Lean mass (kg) Secondary outcomes: Lean mass index (kg/m2); Appendicular lean mass index (kg/m2); Fat mass index (kg/m2); Fat mass (kg); Visceral adipose tissue (k

Collected: 4/15/2026n=100Extraction: medium
News sourcediarrhea

Reuters — GLP-1 weight loss, side effects linked to genetic variations - Reuters

GLP-1 weight loss, side effects linked to genetic variations - Reuters Source: Reuters Published: Fri, 10 Apr 2026 20:08:12 GMT GLP-1 weight loss, side effects linked to genetic variations  Reuters

Collected: 4/15/2026Extraction: low
User reportemotional_blunting

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Collected: 4/15/2026Extraction: medium
User reportemotional_blunting

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Collected: 4/15/2026Extraction: low
User reportemotional_blunting

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 25M. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyway possible, but

Collected: 4/15/2026Extraction: medium
User reportemotional_bluntingsevere

Reddit r/Mounjaro — I feel like a terrible person and I am at my wits end.

To start off, I'm 24M turning 25 soon. I live in Australia. I am diagnosed with depression, generalised anxiety disorder OCD and Auditory Processing Disorder (APD a precursor to autism). I live with my parents. I have been taking the full dose of fluoxetine for 4 years and I see a psychologist for years and my next appointment with him is in 2 weeks. And I have disability support/ employment because of my APD. My relationship with my parents is good at the moment, we support each other in anyw

Collected: 4/15/2026n=1Extraction: medium
Clinical studyconstipation

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Collected: 4/15/2026Extraction: low
Clinical studydiarrhea

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Collected: 4/15/2026Extraction: low
Clinical studyvomiting

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Collected: 4/15/2026Extraction: low
User reportconstipation

Twitter/X — Learn about some effective ways to manage common GLP-1 side effects—like nausea

Tweet/X post: Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCare - x.com Published: Fri, 16 May 2025 07:00:00 GMT Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCa

Collected: 4/14/2026Extraction: low
User reportnausea

Twitter/X — Learn about some effective ways to manage common GLP-1 side effects—like nausea

Tweet/X post: Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCare - x.com Published: Fri, 16 May 2025 07:00:00 GMT Learn about some effective ways to manage common GLP-1 side effects—like nausea and constipation—so you can stay focused on your health and well-being. ihealthunifiedcare.com/articles/manag… #GLP1 #iHealth #UnifiedCa

Collected: 4/14/2026Extraction: low
User reportdizzinessmild

Twitter/X — GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs w

Tweet/X post: GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects both mild and serious to taking GLP-1 drugs, including nausea and dizziness t - x.com Published: Wed, 01 Apr 2026 06:17:59 GMT GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects b

Collected: 4/14/2026Extraction: medium
User reportnauseamild

Twitter/X — GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs w

Tweet/X post: GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects both mild and serious to taking GLP-1 drugs, including nausea and dizziness t - x.com Published: Wed, 01 Apr 2026 06:17:59 GMT GLP-1 drugs must be taken under medical supervision. The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications. There are various side-effects b

Collected: 4/14/2026Extraction: medium
User reportconstipation

Twitter/X — Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Su

Tweet/X post: Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio) #GLP1 #GutHealth #Semaglutide #LowFODMAP - x.com Published: Sat, 21 Mar 2026 07:00:00 GMT Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio

Collected: 4/14/2026Extraction: medium
User reportnausea

Twitter/X — Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Su

Tweet/X post: Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio) #GLP1 #GutHealth #Semaglutide #LowFODMAP - x.com Published: Sat, 21 Mar 2026 07:00:00 GMT Starting a GLP-1? Expect gut changes like nausea, bloating, and constipation. Support digestion with enzymes, probiotics, low-FODMAP fiber, and hydration. Shop GLP-1 Digestive Support (link in bio

Collected: 4/14/2026Extraction: medium
User reportmuscle_losssevere

Twitter/X — JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely

Tweet/X post: JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely walk. Instead I am reduced to crawling on my hands and knees. I never saw this devastating side-effect coming... - x.com Published: Wed, 03 Dec 2025 08:00:00 GMT JENNI MURRAY: After one year on Mounjaro, I have lost six stone but I can barely walk. Instead I am reduced to crawling on my hands and knees. I never saw this devastating side-effect coming...  x.com

Collected: 4/14/2026n=1Extraction: high
User reportvision_losssevere

Twitter/X — Ozempic and Mounjaro linked to vision loss—new study Research has connected the

Tweet/X post: Ozempic and Mounjaro linked to vision loss—new study Research has connected the diabetes and weight-loss drugs Ozempic and Mounjaro to a rare eye condition called NAION, which can cause permanent vision loss. Although diabetes itself can cause blin - x.com Published: Tue, 11 Feb 2025 08:00:00 GMT Ozempic and Mounjaro linked to vision loss—new study Research has connected the diabetes and weight-loss drugs Ozempic and Mounjaro to a rare eye condition called NAION, which can cause

Collected: 4/14/2026Extraction: low
User reportemotional_blunting

Twitter/X — Is a new weight-loss drug making people fall out of love? A recent TikTok video

Tweet/X post: Is a new weight-loss drug making people fall out of love? A recent TikTok video shows a man in a black baseball cap, with text over the video stating: “strange effects of Reta” and “ruining relationships”. He is referring to retatrutide, an experimental weight-loss - x.com Published: Tue, 07 Apr 2026 07:39:45 GMT Is a new weight-loss drug making people fall out of love? A recent TikTok video shows a man in a black baseball cap, with text over the video stating: “strange effects o

Collected: 4/13/2026Extraction: low
User reportnausea

Twitter/X — The weight you lose and the nausea you experience from GLP-1 drugs may be linked

Tweet/X post: The weight you lose and the nausea you experience from GLP-1 drugs may be linked to common gene variants, but they can’t fully explain why some people lose more weight than others - x.com Published: Wed, 08 Apr 2026 15:05:04 GMT The weight you lose and the nausea you experience from GLP-1 drugs may be linked to common gene variants, but they can’t fully explain why some people lose more weight than others  x.com

Collected: 4/13/2026Extraction: low
User reportnausea

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Collected: 4/13/2026Extraction: low
User reportconstipation

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Collected: 4/13/2026Extraction: low
User reportheadache

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Collected: 4/13/2026Extraction: low
User reportfatigue

Quora — Have you ever experienced side-effects like fatigue, headache, irritability, con

Quora Q&A: Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them? - Quora Published: Sun, 17 Mar 2024 07:00:00 GMT Have you ever experienced side-effects like fatigue, headache, irritability, constipation, or nausea while on a weight loss diet? How did you manage them?  Quora

Collected: 4/13/2026Extraction: low
User reportreduced_appetitemild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I'm in my fifth week taking injections. I've been on 2000mg metformin daily for 4 years but my A1C has been creeping up over the last year (7.3) and my fasting blood sugars (morning) had averaged around 160 and almost never registering below 150 and too often above 170. Over the last 4 weeks, my fasting sugars have steadily dropped. Last week they averaged 116 and this week they are averaging 107. I've experienced sporadi

Collected: 4/13/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 8 / 10 For Type 2 Diabetes "I'm in my fifth week taking injections. I've been on 2000mg metformin daily for 4 years but my A1C has been creeping up over the last year (7.3) and my fasting blood sugars (morning) had averaged around 160 and almost never registering below 150 and too often above 170. Over the last 4 weeks, my fasting sugars have steadily dropped. Last week they averaged 116 and this week they are averaging 107. I've experienced sporadi

Collected: 4/13/2026n=1Extraction: high
User reportreduced_appetite

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 9 months now. My A1c's came down from 12 to 6.5. My sugar is always around 90-100 and never drops. I feel fantastic. I've dropped 60 lbs and eat when I want and never finish a meal. I ride my bike 20 miles with no issues."

Collected: 4/13/2026n=1Extraction: high
User reportconstipationmild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I have been on Byetta since August last year and except for some nausea and slight constipation have found it to be a miracle for me. My sugar levels have improved and also have halved my blood pressure medication. Also my eyesight has improved greatly. I have lost 30kg and am feeling great. Thanks Byetta!"

Collected: 4/13/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I have been on Byetta since August last year and except for some nausea and slight constipation have found it to be a miracle for me. My sugar levels have improved and also have halved my blood pressure medication. Also my eyesight has improved greatly. I have lost 30kg and am feeling great. Thanks Byetta!"

Collected: 4/13/2026n=1Extraction: high
User reportinjection_site_reactionmild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 18 months, and used Byetta for 8 months before that. I switched from the Byetta because I couldn't handle the digestive upset any more, but the results were amazing. My A1c has come down to the 5.7-5.9 level consistently. Fasting BG is in the 80s normally. I haven't had any of the stomach upset with Bydureon. The shots are a pain, and I don't think I like the pen very much since I can't control

Collected: 4/13/2026n=1Extraction: high
User reportabdominal_painmoderate

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I've been on Bydureon for 18 months, and used Byetta for 8 months before that. I switched from the Byetta because I couldn't handle the digestive upset any more, but the results were amazing. My A1c has come down to the 5.7-5.9 level consistently. Fasting BG is in the 80s normally. I haven't had any of the stomach upset with Bydureon. The shots are a pain, and I don't think I like the pen very much since I can't control

Collected: 4/13/2026n=1Extraction: high
User reportinjection_site_reactionmild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 10 / 10 For Type 2 Diabetes "I have been on Bydureon since 11/12. My A1c has gone from 9.5 to 6.0, and I am off of all insulin. When I first started the med, I was 5'2" and 187 pounds. I am now just over 10 months later 138 lbs. This has worked miracles for me as none of the oral medications helped me at all. I have not had any side effects. The shot is a bit painful, but I've found if you let it warm up about 15 minutes, it's a little easier. I do

Collected: 4/13/2026n=1Extraction: high
User reportabdominal_painmoderate

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Collected: 4/13/2026n=1Extraction: high
User reportacid_refluxmild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Collected: 4/13/2026n=1Extraction: high
User reportreduced_appetitemoderate

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Collected: 4/13/2026n=1Extraction: high
User reportnauseamoderate

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "Had taken my 4th injection of Bydureon. No problems at the injection site, but after my 3rd injection, I began to feel sick all the time. No appetite at all, not even coffee. Had persistent bloating, heartburn, and a bad taste in my mouth. Stopped craving sweets and carbs. A1c went from 8.5 to 6.3 in 4 weeks. Blood sugars down from 166-180 to 120-125. Love the way this medication works, but can hardly tolerate the discomf

Collected: 4/13/2026n=1Extraction: high
User reportinjection_site_reactionmild

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I am enjoying the results of Bydureon - 5th shot is tomorrow. I've lost 19 lbs and sometimes have to make myself eat something. Bydureon is helping me eat very healthy, and I've lost my cravings for sweets and carbs. My sugars have dropped from 220-300 range to 90-110 range. I have energy to spare. I also take 500 mg of Metformin twice a day. No issues with lumps, but the medicine does burn at times when injected."

Collected: 4/13/2026n=1Extraction: high
User reportreduced_appetite

Drugs.com Review — exenatide — General

Patient review for exenatide — Rating: 9 / 10 For Type 2 Diabetes "I am enjoying the results of Bydureon - 5th shot is tomorrow. I've lost 19 lbs and sometimes have to make myself eat something. Bydureon is helping me eat very healthy, and I've lost my cravings for sweets and carbs. My sugars have dropped from 220-300 range to 90-110 range. I have energy to spare. I also take 500 mg of Metformin twice a day. No issues with lumps, but the medicine does burn at times when injected."

Collected: 4/13/2026n=1Extraction: high
User reportreduced_appetite

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Well, this is my second review on this drug. I am now on my 3rd week of taking Trulicity and can happily report I’m getting on brilliantly, no more side effects, not that there were many anyway, just slight wind and nausea. Very, very easy and painless to inject. Sugar levels gone from 18 to 5.5-6, therefore being able to reduce my daily insulin dose significantly. Appetite cut in half, not really losing weight yet, bu

Collected: 4/13/2026n=1Extraction: high
User reportnauseamild

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Well, this is my second review on this drug. I am now on my 3rd week of taking Trulicity and can happily report I’m getting on brilliantly, no more side effects, not that there were many anyway, just slight wind and nausea. Very, very easy and painless to inject. Sugar levels gone from 18 to 5.5-6, therefore being able to reduce my daily insulin dose significantly. Appetite cut in half, not really losing weight yet, bu

Collected: 4/13/2026n=1Extraction: high
User reportnausea

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "I started Trulicity last week. I was a bit nervous before using it because so many people complained of gastric distress. I am very pleased to say I had no problem with the Trulicity. No gastric issues, the injection is painless, and best of all, my blood sugar is actually in a normal range. I'm so glad my physician suggested I try Trulicity."

Collected: 4/13/2026n=1Extraction: medium
User reportreduced_appetitemild

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 10 / 10 For Type 2 Diabetes "Update to earlier post. It's now been 5 weeks since starting Trulicity and happy to report the side effects have mostly disappeared. My appetite is very subdued. Blood sugar levels ranging between 3.4 and 6.5. Weight has reduced further. Another 7 lb shed in 2 weeks. Total weight loss now 17 pounds. All very positive. This drug works great for me. Everyone reacts differently to new meds but it's so worth a go. Make it

Collected: 4/13/2026n=1Extraction: high
User reportacid_refluxmoderate

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Collected: 4/13/2026n=1Extraction: medium
User reportvomitingsevere

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Collected: 4/13/2026n=1Extraction: high
User reportdiarrheasevere

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "I’ve been on Trulicity for 4 months now, and I’m telling you, it is horrible. I have gastroparesis and had my gallbladder out 6 years ago, so of course, all these gastric side effects hit me hard! Last week, I started with the violent diarrhea and vomiting to the point I went to the ER! Of course, my doctor didn’t know why I was so sick! Well, my A1C went from 11 to 9 with this med, and most of the time, it would linger

Collected: 4/13/2026n=1Extraction: high
User report

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "No need for details. I experienced the same awful side effects as many of the posters. So I quit the drug and went on a low-carb diet (little or no grains, starches, or sugar) and started walking 20 minutes every day as fast as I could. Lost 40 lbs. A1C went from 8.0 to 5.5. Never felt better. But I am still diabetic, meaning I cannot go back to my old ways. If I can do it, you can do it. Oh, and the money I am saving!"

Collected: 4/13/2026n=1Extraction: low
User reportnauseamild

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 5 / 10 For Type 2 Diabetes "I must say you guys were scaring me about the negative side effects, so I was weighing up whether or not to start. I realized that I am more than a conqueror, and can overcome any undesirable side effects that come up. Well, about 4 hours later and time to eat, the yucky stomach started. I thought, is it just my mind or is it really the new meds kicking in. I didn't eat much, a good thing. HERE IS WHAT TOOK THE SICK FEE

Collected: 4/13/2026n=1Extraction: high
User reportabdominal_painsevere

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "My husband of over fifty years was put on this drug at the beginning of 2020. He was over 270 pounds, and his A1C was over 11. The doctor was desperate. My husband experienced horrible nausea and abdominal pain. He began to lose weight but not as fast as the doctor wanted. He was put on concentrated insulin twice a day. He started becoming sicker. He was taken to the ER in August of 2020. He was placed on a ventilator f

Collected: 4/13/2026n=1Extraction: high
User reportnauseasevere

Drugs.com Review — dulaglutide — General

Patient review for dulaglutide — Rating: 1 / 10 For Type 2 Diabetes "My husband of over fifty years was put on this drug at the beginning of 2020. He was over 270 pounds, and his A1C was over 11. The doctor was desperate. My husband experienced horrible nausea and abdominal pain. He began to lose weight but not as fast as the doctor wanted. He was put on concentrated insulin twice a day. He started becoming sicker. He was taken to the ER in August of 2020. He was placed on a ventilator f

Collected: 4/13/2026n=1Extraction: high
Clinical studynausea

Guidelines/NICE website — Tirzepatide for managing overweight and obesity - NICE website

Tirzepatide for managing overweight and obesity - NICE website Source: NICE website Published: Mon, 23 Dec 2024 08:00:00 GMT Tirzepatide for managing overweight and obesity  NICE website

Collected: 4/13/2026Extraction: low
Regulatory datapancreatitissevere

MHRA/The Guardian — Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warn

Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warns - The Guardian Source: The Guardian Published: Thu, 29 Jan 2026 08:00:00 GMT Small risk of severe acute pancreatitis with weight-loss jabs, UK regulator warns  The Guardian

Collected: 4/13/2026Extraction: medium
Regulatory datapancreatitissevere

MHRA/Medscape — MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs - Medscape

MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs - Medscape Source: Medscape Published: Fri, 30 Jan 2026 08:00:00 GMT MHRA Warns of Rare Severe Pancreatitis With GLP-1 Drugs  Medscape

Collected: 4/13/2026Extraction: medium
Regulatory datapancreatitis

MHRA/European Medical Journal — Acute Pancreatitis Warnings Strengthened on GLP-1RAs - European Medical Journal

Acute Pancreatitis Warnings Strengthened on GLP-1RAs - European Medical Journal Source: European Medical Journal Published: Sat, 07 Feb 2026 08:00:00 GMT Acute Pancreatitis Warnings Strengthened on GLP-1RAs  European Medical Journal

Collected: 4/13/2026Extraction: low
Regulatory datapancreatitissevere

MHRA/Pulse Today — MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis - P

MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis - Pulse Today Source: Pulse Today Published: Fri, 30 Jan 2026 08:00:00 GMT MHRA issues safety alert on weight-loss jabs and risk of severe pancreatitis  Pulse Today

Collected: 4/13/2026Extraction: medium
Clinical studynausea

PubMed India — 10.1001/jamainternmed.2025.3599.

JAMA Intern Med. 2025 Oct 1;185(10):1206-1217. doi: 10.1001/jamainternmed.2025.3599. Oral Semaglutide in an East Asian Population With Overweight or Obesity, With or Without Type 2 Diabetes: The OASIS 2 Randomized Clinical Trial. Kadowaki T(1), Heftdal LD(2), Ko HJ(3), Overvad M(2), Shimomura I(4), Thamattoor UK(5), Kim KK(6); OASIS 2 Investigators. Collaborators: Kunishige H, Okude J, Sato N, Takeda S, Uemura K, Osonoi T, Isshiki S, Ito N, Naito H, Oka N, Hosoya M, Saito M, Takizawa H, A

Collected: 4/13/2026Extraction: low
News sourceemotional_blunting

Think Global Health — The Mental Health Effects of Ozempic and GLP-1 Drugs - Think Global Health

The Mental Health Effects of Ozempic and GLP-1 Drugs - Think Global Health Source: Think Global Health Published: Thu, 04 Dec 2025 08:00:00 GMT The Mental Health Effects of Ozempic and GLP-1 Drugs  Think Global Health

Collected: 4/13/2026Extraction: low
Regulatory dataoff_label_use_report7%

FDA FAERS — semaglutide — OFF LABEL USE

FDA adverse event reports for semaglutide: OFF LABEL USE reported 6855 times out of 99460 total reports (6.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/13/2026n=99460Extraction: high
User reportweight_regain

Reddit r/compoundedtirzepatide — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Collected: 4/13/2026Dose: highExtraction: medium
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Collected: 4/13/2026Dose: highExtraction: high
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Collected: 4/13/2026Extraction: medium
User reportinjection_site_reactionmild

Reddit r/compoundedtirzepatide — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Collected: 4/13/2026Extraction: medium
User reportnauseamild

Reddit r/semaglutide — Extreme Fatigue

Currently 8 weeks pregnant and I don’t have much symptoms just sore breasts and increased appetite. The nausea has subsided ALOT, BUT the fatigue is crazy…. I can barely even get up to go take a shower because it sounds like too much work. I am someone that is constantly on the go, loves to cook and I can’t even move from the couch to get to my bed!!! It is so bad I am ordering pre cooked rice and chicken breast from chic fila because there is just no energy. Is this normal? When will it passss

Collected: 4/13/2026n=1Extraction: high
User reportfatiguesevere

Reddit r/semaglutide — Extreme Fatigue

Currently 8 weeks pregnant and I don’t have much symptoms just sore breasts and increased appetite. The nausea has subsided ALOT, BUT the fatigue is crazy…. I can barely even get up to go take a shower because it sounds like too much work. I am someone that is constantly on the go, loves to cook and I can’t even move from the couch to get to my bed!!! It is so bad I am ordering pre cooked rice and chicken breast from chic fila because there is just no energy. Is this normal? When will it passss

Collected: 4/13/2026n=1Extraction: high
User reportweight_regain

Reddit r/WegovyWeightLoss — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Collected: 4/13/2026Dose: highExtraction: medium
User reportinjection_site_reactionmild

Reddit r/WegovyWeightLoss — Mounjaro rash

I’ve been on it since September 2025 (now at 7.5mg) and in the last month have noticed a red dry patch at three different injection sites - both sides of my belly and left thigh. Doesn’t really itch until I start touching these spots. I’ve seen these mentioned as a side effect but the impression I have is that they go away on their own but so far they haven’t. I don’t want to inject in my arms in case the same thing happens and that’s more visible. FWIW - I’m not losing weight anymore and cra

Collected: 4/13/2026Dose: highExtraction: high
User reportinjection_site_reaction

Reddit r/WegovyWeightLoss — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Collected: 4/13/2026Extraction: medium
User reportinjection_site_reaction

Reddit r/WegovyWeightLoss — Best glp-1 injection sites for less soreness?

Soreness and bruising from GLP-1 injections usually come from technique rather than the medication itself. Pinching a small fold of skin, inserting at a 45 degree angle for leaner builds, and letting the pen warm to room temperature before injecting all reduce discomfort measurably. The abdomen is the most comfortable starting site for most people on compounded semaglutide or tirzepatide. Rotating through the upper thigh and outer arm prevents tissue buildup that degrades how the medication abs

Collected: 4/13/2026Extraction: medium
Clinical studynausea

PubMed — Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity.

N Engl J Med. 2024 Oct 3;391(13):1193-1205. doi: 10.1056/NEJMoa2404881. Epub 2024 Jun 21. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. Malhotra A(1), Grunstein RR(1), Fietze I(1), Weaver TE(1), Redline S(1), Azarbarzin A(1), Sands SA(1), Schwab RJ(1), Dunn JP(1), Chakladar S(1), Bunck MC(1), Bednarik J(1); SURMOUNT-OSA Investigators. Collaborators: Eckert DJ, Grunstein RR, Santos Canani LH, Halpern B, Cercato C, Delgado Fernandes M, Alves BB, Kerr Saraiva JF, Reis

Collected: 4/13/2026Extraction: low
User reportemotional_blunting12%moderate

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Emotional blunting / Reduced pleasure: 12%. Widely discussed on Reddit and forums but absent from clinical trial data. Users describe feeling 'flat' — less joy from food but also from music, socialising, and other activities. Some find it distressing, others see it as a neutral side effect.

Collected: 4/12/2026Extraction: medium
News sourceemotional_blunting5%moderate

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: highn=300Extraction: high
News sourceemotional_blunting3%moderate

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
News sourceemotional_blunting2%moderate

NYT 'Ozempic Changed My Personality' investigation (2025)

Emotional blunting / Reduced pleasure: clinical rate of 2% at low dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyemotional_blunting5%moderate

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyemotional_blunting3%moderate

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyemotional_blunting2%moderate

GLP-1 receptor CNS expression review (Neuroscience & Biobehavioral Reviews 2024)

Emotional blunting / Reduced pleasure: clinical rate of 2% at low dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportemotional_blunting5%moderate

Reddit r/Ozempic emotional blunting megathread (2024-2026)

Emotional blunting / Reduced pleasure: clinical rate of 5% at high dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportemotional_blunting3%moderate

Reddit r/Ozempic emotional blunting megathread (2024-2026)

Emotional blunting / Reduced pleasure: clinical rate of 3% at medium dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportemotional_blunting2%moderate

Reddit r/Ozempic emotional blunting megathread (2024-2026)

Emotional blunting / Reduced pleasure: clinical rate of 2% at low dose. Reduced emotional response to pleasurable experiences — not just food, but also hobbies, social activities, or intimacy. GLP-1 receptors in the brain's reward pathway may dampen dopamine-mediated pleasure. Not well-studied in clinical trials.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportdizziness14%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Dizziness: 14%. Users link it mostly to not drinking enough water or standing up too quickly. People on blood pressure medication should monitor closely as weight loss can lower BP further.

Collected: 4/12/2026Extraction: medium
News sourcedizziness5%mild

PCOM Safety review (2025)

Dizziness: clinical rate of 5% at high dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: highn=300Extraction: high
News sourcedizziness3%mild

PCOM Safety review (2025)

Dizziness: clinical rate of 3% at medium dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
News sourcedizziness2%mild

PCOM Safety review (2025)

Dizziness: clinical rate of 2% at low dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportdizziness5%mild

Reddit r/Ozempic dizziness reports (2024-2026)

Dizziness: clinical rate of 5% at high dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportdizziness3%mild

Reddit r/Ozempic dizziness reports (2024-2026)

Dizziness: clinical rate of 3% at medium dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportdizziness2%mild

Reddit r/Ozempic dizziness reports (2024-2026)

Dizziness: clinical rate of 2% at low dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studydizziness5%mild

STEP-2 Trial (Davies et al., Lancet 2021)

Dizziness: clinical rate of 5% at high dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studydizziness3%mild

STEP-2 Trial (Davies et al., Lancet 2021)

Dizziness: clinical rate of 3% at medium dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studydizziness2%mild

STEP-2 Trial (Davies et al., Lancet 2021)

Dizziness: clinical rate of 2% at low dose. Feeling lightheaded or unsteady. Often related to dehydration from reduced fluid/food intake or blood pressure changes during weight loss.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportinjection_site_reaction12%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Injection site reaction: 12%. Generally mild. Users describe small red bumps or slight itching that resolve within 1-2 days. Rotating injection sites helps. Rarely a reason to stop treatment.

Collected: 4/12/2026Extraction: medium
User reportinjection_site_reaction5%mild

Diabetes forum injection site discussions (2024-2026)

Injection site reaction: clinical rate of 5% at high dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportinjection_site_reaction4%mild

Diabetes forum injection site discussions (2024-2026)

Injection site reaction: clinical rate of 4% at medium dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportinjection_site_reaction3%mild

Diabetes forum injection site discussions (2024-2026)

Injection site reaction: clinical rate of 3% at low dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyinjection_site_reaction5%mild

SURMOUNT-2 Trial (Garvey et al., Lancet 2023)

Injection site reaction: clinical rate of 5% at high dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyinjection_site_reaction4%mild

SURMOUNT-2 Trial (Garvey et al., Lancet 2023)

Injection site reaction: clinical rate of 4% at medium dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyinjection_site_reaction3%mild

SURMOUNT-2 Trial (Garvey et al., Lancet 2023)

Injection site reaction: clinical rate of 3% at low dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyinjection_site_reaction5%mild

STEP-1 Trial (Wilding et al., NEJM 2021)

Injection site reaction: clinical rate of 5% at high dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyinjection_site_reaction4%mild

STEP-1 Trial (Wilding et al., NEJM 2021)

Injection site reaction: clinical rate of 4% at medium dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyinjection_site_reaction3%mild

STEP-1 Trial (Wilding et al., NEJM 2021)

Injection site reaction: clinical rate of 3% at low dose. Redness, itching, swelling, or mild pain at the injection site. Usually mild and self-resolving within a few days.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reporthair_loss15%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Hair loss (thinning): 15%. Much more commonly reported by users than clinical trials suggest (~3% in SELECT trial). Forum users describe increased shedding starting around month 3-4. Most say it stabilises once weight loss plateaus.

Collected: 4/12/2026Extraction: medium
News sourcehair_loss3%mild

RAND Corporation side effects study (2025)

Hair loss (thinning): clinical rate of 3% at high dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: highn=300Extraction: high
News sourcehair_loss2%mild

RAND Corporation side effects study (2025)

Hair loss (thinning): clinical rate of 2% at medium dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
News sourcehair_loss1%mild

RAND Corporation side effects study (2025)

Hair loss (thinning): clinical rate of 1% at low dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reporthair_loss3%mild

Reddit r/Ozempic hair loss megathread (2024-2026)

Hair loss (thinning): clinical rate of 3% at high dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reporthair_loss2%mild

Reddit r/Ozempic hair loss megathread (2024-2026)

Hair loss (thinning): clinical rate of 2% at medium dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reporthair_loss1%mild

Reddit r/Ozempic hair loss megathread (2024-2026)

Hair loss (thinning): clinical rate of 1% at low dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyhair_loss3%mild

SELECT Trial (Lincoff et al., NEJM 2023)

Hair loss (thinning): clinical rate of 3% at high dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyhair_loss2%mild

SELECT Trial (Lincoff et al., NEJM 2023)

Hair loss (thinning): clinical rate of 2% at medium dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyhair_loss1%mild

SELECT Trial (Lincoff et al., NEJM 2023)

Hair loss (thinning): clinical rate of 1% at low dose. Noticeable hair thinning or shedding (telogen effluvium). Likely caused by nutritional deficiency from rapid weight loss and reduced caloric intake, not a direct drug effect.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportgallstones4%severe

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Gallstones (cholelithiasis): 4%. Users who develop gallstones typically describe it as sudden, intense pain in the upper right abdomen — often after a fatty meal. Some required surgery (cholecystectomy). More common in those losing weight rapidly.

Collected: 4/12/2026Extraction: medium
User reportgallstones3%severe

Reddit r/Ozempic gallbladder removal posts (2024-2026)

Gallstones (cholelithiasis): clinical rate of 3% at high dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportgallstones2%severe

Reddit r/Ozempic gallbladder removal posts (2024-2026)

Gallstones (cholelithiasis): clinical rate of 2% at medium dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportgallstones1%severe

Reddit r/Ozempic gallbladder removal posts (2024-2026)

Gallstones (cholelithiasis): clinical rate of 1% at low dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: lown=200Extraction: high
News sourcegallstones3%severe

FDA safety communication on GLP-1 and gallbladder events (2024)

Gallstones (cholelithiasis): clinical rate of 3% at high dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: highn=300Extraction: high
News sourcegallstones2%severe

FDA safety communication on GLP-1 and gallbladder events (2024)

Gallstones (cholelithiasis): clinical rate of 2% at medium dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
News sourcegallstones1%severe

FDA safety communication on GLP-1 and gallbladder events (2024)

Gallstones (cholelithiasis): clinical rate of 1% at low dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studygallstones3%severe

STEP-1 Trial (Wilding et al., NEJM 2021)

Gallstones (cholelithiasis): clinical rate of 3% at high dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studygallstones2%severe

STEP-1 Trial (Wilding et al., NEJM 2021)

Gallstones (cholelithiasis): clinical rate of 2% at medium dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studygallstones1%severe

STEP-1 Trial (Wilding et al., NEJM 2021)

Gallstones (cholelithiasis): clinical rate of 1% at low dose. Formation of gallstones in the gallbladder. Associated with rapid weight loss rather than the drug directly. Symptoms include sharp pain in the upper right abdomen after eating fatty foods. Requires medical attention.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportacid_reflux20%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Acid reflux (GERD): 20%. Users with pre-existing GERD report significant worsening. Those without prior reflux may develop it temporarily. Sleeping with the head elevated and avoiding late meals helps.

Collected: 4/12/2026Extraction: medium
News sourceacid_reflux8%mild

Washington University GI side effects study (2025)

Acid reflux (GERD): clinical rate of 8% at high dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: highn=300Extraction: high
News sourceacid_reflux5%mild

Washington University GI side effects study (2025)

Acid reflux (GERD): clinical rate of 5% at medium dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
News sourceacid_reflux3%mild

Washington University GI side effects study (2025)

Acid reflux (GERD): clinical rate of 3% at low dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportacid_reflux8%mild

Reddit r/GERD & r/Ozempic cross-posts (2024-2026)

Acid reflux (GERD): clinical rate of 8% at high dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportacid_reflux5%mild

Reddit r/GERD & r/Ozempic cross-posts (2024-2026)

Acid reflux (GERD): clinical rate of 5% at medium dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportacid_reflux3%mild

Reddit r/GERD & r/Ozempic cross-posts (2024-2026)

Acid reflux (GERD): clinical rate of 3% at low dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyacid_reflux8%mild

STEP-3 Trial (Wadden et al., JAMA 2021)

Acid reflux (GERD): clinical rate of 8% at high dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyacid_reflux5%mild

STEP-3 Trial (Wadden et al., JAMA 2021)

Acid reflux (GERD): clinical rate of 5% at medium dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyacid_reflux3%mild

STEP-3 Trial (Wadden et al., JAMA 2021)

Acid reflux (GERD): clinical rate of 3% at low dose. Stomach acid flowing back into the oesophagus, causing heartburn or a burning sensation. GLP-1 drugs slow gastric emptying, which can worsen pre-existing reflux.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportabdominal_pain18%moderate

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Abdominal pain: 18%. Users describe it as a dull ache in the upper stomach, especially after eating. Most say it's tolerable but uncomfortable. Important: sharp or severe pain is different — seek help immediately.

Collected: 4/12/2026Extraction: medium
User reportabdominal_pain7%moderate

Reddit r/Ozempic user reports on stomach pain (2024-2026)

Abdominal pain: clinical rate of 7% at high dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportabdominal_pain5%moderate

Reddit r/Ozempic user reports on stomach pain (2024-2026)

Abdominal pain: clinical rate of 5% at medium dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportabdominal_pain3%moderate

Reddit r/Ozempic user reports on stomach pain (2024-2026)

Abdominal pain: clinical rate of 3% at low dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyabdominal_pain7%moderate

STEP-2 Trial (Davies et al., Lancet 2021)

Abdominal pain: clinical rate of 7% at high dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyabdominal_pain5%moderate

STEP-2 Trial (Davies et al., Lancet 2021)

Abdominal pain: clinical rate of 5% at medium dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyabdominal_pain3%moderate

STEP-2 Trial (Davies et al., Lancet 2021)

Abdominal pain: clinical rate of 3% at low dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyabdominal_pain7%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Abdominal pain: clinical rate of 7% at high dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyabdominal_pain5%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Abdominal pain: clinical rate of 5% at medium dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyabdominal_pain3%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Abdominal pain: clinical rate of 3% at low dose. Upper abdominal pain or discomfort. Usually mild but persistent pain should be investigated to rule out more serious conditions like pancreatitis.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportvomiting20%moderate

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Vomiting: 20%. Users who experience vomiting say it typically happens after eating too much or too quickly. Most learn to adapt portion sizes within 1-2 weeks.

Collected: 4/12/2026Extraction: medium
Clinical studyvomiting8%moderate

SURMOUNT-1 Trial (Jastreboff et al., NEJM 2022)

Vomiting: clinical rate of 8% at high dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyvomiting5%moderate

SURMOUNT-1 Trial (Jastreboff et al., NEJM 2022)

Vomiting: clinical rate of 5% at medium dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyvomiting3%moderate

SURMOUNT-1 Trial (Jastreboff et al., NEJM 2022)

Vomiting: clinical rate of 3% at low dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: lown=200Extraction: high
User reportvomiting8%moderate

Reddit r/Ozempic & r/Mounjaro vomiting threads (2024-2026)

Vomiting: clinical rate of 8% at high dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: highn=300Extraction: high
User reportvomiting5%moderate

Reddit r/Ozempic & r/Mounjaro vomiting threads (2024-2026)

Vomiting: clinical rate of 5% at medium dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
User reportvomiting3%moderate

Reddit r/Ozempic & r/Mounjaro vomiting threads (2024-2026)

Vomiting: clinical rate of 3% at low dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyvomiting8%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Vomiting: clinical rate of 8% at high dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: highn=300Extraction: high
Clinical studyvomiting5%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Vomiting: clinical rate of 5% at medium dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: mediumn=500Extraction: high
Clinical studyvomiting3%moderate

STEP-1 Trial (Wilding et al., NEJM 2021)

Vomiting: clinical rate of 3% at low dose. Actively throwing up, beyond just feeling nauseous. More severe than nausea and often co-occurs with it. Usually dose-dependent.

Collected: 4/12/2026Dose: lown=200Extraction: high
Clinical studyreduced_appetite22%mild

Nature — Genetic predictors of GLP1 receptor agonist weight loss and side effects (2026)

GWAS of 27,885 GLP1 RA users. GLP1R missense variant: additional -0.76 kg weight loss per allele copy (P=2.9e-10). Average BMI reduction 10.2%. 4.9% achieved >25% reduction. Genetic variation predicts differential appetite suppression efficacy.

Collected: 4/12/2026n=27885Extraction: high
Clinical studyvomiting8%moderate

Nature — Genetic predictors of GLP1 receptor agonist weight loss and side effects (2026)

GWAS of 27,885 GLP1 RA users. GIPR missense variant rs1800437 associated with vomiting in tirzepatide users (P=5.1e-9). GLP1R locus variants associated with differential vomiting risk across all GLP1 RAs.

Collected: 4/12/2026n=27885Extraction: high
Clinical studynausea35%moderate

Nature — Genetic predictors of GLP1 receptor agonist weight loss and side effects (2026)

GWAS of 27,885 GLP1 RA users. GLP1R missense variant associated with differential nausea risk. GIPR variant (rs1800437) associated with nausea specifically in tirzepatide users (P=5.1e-9). Women: ΔBMI -12.2% vs men -10.0%.

Collected: 4/12/2026n=27885Extraction: high
News sourceweight_regain

Reuters — GLP-1 weight loss, side effects linked to genetic variations - Reuters

GLP-1 weight loss, side effects linked to genetic variations - Reuters Source: Reuters Published: Fri, 10 Apr 2026 20:08:12 GMT GLP-1 weight loss, side effects linked to genetic variations  Reuters

Collected: 4/12/2026Extraction: low
News sourcenausea

Yale Medicine — GLP-1 Weight-Loss Pills: What You Need to Know - Yale Medicine

GLP-1 Weight-Loss Pills: What You Need to Know - Yale Medicine Source: Yale Medicine Published: Fri, 10 Apr 2026 18:20:51 GMT GLP-1 Weight-Loss Pills: What You Need to Know  Yale Medicine

Collected: 4/12/2026Extraction: low
News sourceconstipation

2 Minute Medicine — Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal ad

Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk - 2 Minute Medicine Source: 2 Minute Medicine Published: Sun, 23 Nov 2025 08:00:00 GMT Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk  2 Minute Medicine

Collected: 4/12/2026Extraction: low
Regulatory data7%

FDA FAERS — semaglutide — OFF LABEL USE

FDA adverse event reports for semaglutide: OFF LABEL USE reported 6855 times out of 99460 total reports (6.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=99460Extraction: medium
Clinical studyvomiting

ClinicalTrials.gov — Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide

Clinical trial: Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2) NCT ID: NCT07220629 Status: ACTIVE_NOT_RECRUITING Phase: PHASE2 Enrollment: 82 participants Conditions: Obesity Interventions: NT-0796, Placebo Primary outcomes: Assess the safety and tolerability of NT-0796 as an adjunct to semaglutide in participants with obesity by assessing AEs and SAEs, symptoms of nausea and vomiting, clinical laboratory parameters, vita

Collected: 4/12/2026n=82Extraction: high
Clinical studynausea

ClinicalTrials.gov — Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide

Clinical trial: Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2) NCT ID: NCT07220629 Status: ACTIVE_NOT_RECRUITING Phase: PHASE2 Enrollment: 82 participants Conditions: Obesity Interventions: NT-0796, Placebo Primary outcomes: Assess the safety and tolerability of NT-0796 as an adjunct to semaglutide in participants with obesity by assessing AEs and SAEs, symptoms of nausea and vomiting, clinical laboratory parameters, vita

Collected: 4/12/2026n=82Extraction: high
Clinical studyinjection_site_reaction

ClinicalTrials.gov — Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc

Clinical trial: Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc NCT ID: NCT04189848 Status: COMPLETED Phase: PHASE4 Enrollment: 104 participants Conditions: Healthy Volunteers, Diabetes Mellitus, Type 2, Overweight, Obesity Interventions: Semaglutide, Dulaglutide Primary outcomes: Intensity of Injection Site Pain Secondary outcomes: Summary: This study in healthy men and women looks at the injection site experience of semaglutide and dulaglutide given subcutaneou

Collected: 4/12/2026Dose: lown=104Extraction: medium
Clinical studyinjection_site_reaction

ClinicalTrials.gov — Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc

Clinical trial: Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc NCT ID: NCT04189848 Status: COMPLETED Phase: PHASE4 Enrollment: 104 participants Conditions: Healthy Volunteers, Diabetes Mellitus, Type 2, Overweight, Obesity Interventions: Semaglutide, Dulaglutide Primary outcomes: Intensity of Injection Site Pain Secondary outcomes: Summary: This study in healthy men and women looks at the injection site experience of semaglutide and dulaglutide given subcutaneou

Collected: 4/12/2026Dose: lown=104Extraction: medium
News sourcenausea

Reuters — GLP-1 weight loss, side effects linked to genetic variations - Reuters

GLP-1 weight loss, side effects linked to genetic variations - Reuters Source: Reuters Published: Fri, 10 Apr 2026 20:08:12 GMT GLP-1 weight loss, side effects linked to genetic variations  Reuters

Collected: 4/12/2026Extraction: low
Regulatory dataweight_loss3%

FDA FAERS — dulaglutide — WEIGHT DECREASED

FDA adverse event reports for dulaglutide: WEIGHT DECREASED reported 3349 times out of 101618 total reports (3.3%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory dataoff_label_use7%

FDA FAERS — semaglutide — OFF LABEL USE

FDA adverse event reports for semaglutide: OFF LABEL USE reported 6855 times out of 99460 total reports (6.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=99460Extraction: high
News sourcevomiting

2 Minute Medicine — Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal ad

Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk - 2 Minute Medicine Source: 2 Minute Medicine Published: Sun, 23 Nov 2025 08:00:00 GMT Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk  2 Minute Medicine

Collected: 4/12/2026Extraction: low
News sourcediarrhea

2 Minute Medicine — Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal ad

Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk - 2 Minute Medicine Source: 2 Minute Medicine Published: Sun, 23 Nov 2025 08:00:00 GMT Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk  2 Minute Medicine

Collected: 4/12/2026Extraction: low
News sourcenausea

2 Minute Medicine — Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal ad

Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk - 2 Minute Medicine Source: 2 Minute Medicine Published: Sun, 23 Nov 2025 08:00:00 GMT Dulaglutide, semaglutide, and tirzepatide exhibit comparable gastrointestinal adverse event risk  2 Minute Medicine

Collected: 4/12/2026Extraction: low
News sourceemotional_blunting

MSN — GLP-1 patients report new side effect—and it’s hitting relationships hard - MSN

GLP-1 patients report new side effect—and it’s hitting relationships hard - MSN Source: MSN Published: Fri, 10 Apr 2026 18:01:03 GMT GLP-1 patients report new side effect—and it’s hitting relationships hard  MSN

Collected: 4/12/2026Extraction: low
Regulatory data8%

FDA FAERS — lixisenatide — OFF LABEL USE

FDA adverse event reports for lixisenatide: OFF LABEL USE reported 251 times out of 3364 total reports (7.5%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: low
Regulatory datavomiting2%

FDA FAERS — lixisenatide — VOMITING

FDA adverse event reports for lixisenatide: VOMITING reported 72 times out of 3364 total reports (2.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: high
Regulatory datadiarrhea2%

FDA FAERS — lixisenatide — DIARRHOEA

FDA adverse event reports for lixisenatide: DIARRHOEA reported 72 times out of 3364 total reports (2.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: high
Regulatory datainjection_site_reaction2%

FDA FAERS — lixisenatide — INJECTION SITE PAIN

FDA adverse event reports for lixisenatide: INJECTION SITE PAIN reported 73 times out of 3364 total reports (2.2%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: high
Regulatory datavisual_impairment4%

FDA FAERS — lixisenatide — VISUAL IMPAIRMENT

FDA adverse event reports for lixisenatide: VISUAL IMPAIRMENT reported 140 times out of 3364 total reports (4.2%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: high
Regulatory datanausea4%

FDA FAERS — lixisenatide — NAUSEA

FDA adverse event reports for lixisenatide: NAUSEA reported 142 times out of 3364 total reports (4.2%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=3364Extraction: high
Regulatory datafatigue2%

FDA FAERS — exenatide — FATIGUE

FDA adverse event reports for exenatide: FATIGUE reported 1759 times out of 94688 total reports (1.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datainjection_site_reaction2%

FDA FAERS — exenatide — INJECTION SITE HAEMORRHAGE

FDA adverse event reports for exenatide: INJECTION SITE HAEMORRHAGE reported 1809 times out of 94688 total reports (1.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datainjection_site_reaction2%

FDA FAERS — exenatide — INJECTION SITE BRUISING

FDA adverse event reports for exenatide: INJECTION SITE BRUISING reported 1843 times out of 94688 total reports (1.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datapancreatitis2%

FDA FAERS — exenatide — PANCREATITIS

FDA adverse event reports for exenatide: PANCREATITIS reported 2011 times out of 94688 total reports (2.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datainjection_site_reaction2%

FDA FAERS — exenatide — INJECTION SITE PAIN

FDA adverse event reports for exenatide: INJECTION SITE PAIN reported 2023 times out of 94688 total reports (2.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory dataheadache2%

FDA FAERS — exenatide — HEADACHE

FDA adverse event reports for exenatide: HEADACHE reported 2086 times out of 94688 total reports (2.2%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datadizziness3%

FDA FAERS — exenatide — DIZZINESS

FDA adverse event reports for exenatide: DIZZINESS reported 2673 times out of 94688 total reports (2.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datadiarrhea3%

FDA FAERS — exenatide — DIARRHOEA

FDA adverse event reports for exenatide: DIARRHOEA reported 2743 times out of 94688 total reports (2.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datavomiting5%

FDA FAERS — exenatide — VOMITING

FDA adverse event reports for exenatide: VOMITING reported 4346 times out of 94688 total reports (4.6%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datareduced_appetite6%

FDA FAERS — exenatide — DECREASED APPETITE

FDA adverse event reports for exenatide: DECREASED APPETITE reported 5643 times out of 94688 total reports (6.0%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datanausea13%

FDA FAERS — exenatide — NAUSEA

FDA adverse event reports for exenatide: NAUSEA reported 12040 times out of 94688 total reports (12.7%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory dataweight_regain13%

FDA FAERS — exenatide — WEIGHT DECREASED

FDA adverse event reports for exenatide: WEIGHT DECREASED reported 12123 times out of 94688 total reports (12.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=94688Extraction: high
Regulatory datafatigue2%

FDA FAERS — dulaglutide — FATIGUE

FDA adverse event reports for dulaglutide: FATIGUE reported 2409 times out of 101618 total reports (2.4%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datainjection_site_reaction3%

FDA FAERS — dulaglutide — INJECTION SITE HAEMORRHAGE

FDA adverse event reports for dulaglutide: INJECTION SITE HAEMORRHAGE reported 3132 times out of 101618 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datareduced_appetite3%

FDA FAERS — dulaglutide — DECREASED APPETITE

FDA adverse event reports for dulaglutide: DECREASED APPETITE reported 3153 times out of 101618 total reports (3.1%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory dataweight_regain3%

FDA FAERS — dulaglutide — WEIGHT DECREASED

FDA adverse event reports for dulaglutide: WEIGHT DECREASED reported 3349 times out of 101618 total reports (3.3%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: medium
Regulatory datavomiting5%

FDA FAERS — dulaglutide — VOMITING

FDA adverse event reports for dulaglutide: VOMITING reported 5413 times out of 101618 total reports (5.3%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datadiarrhea6%

FDA FAERS — dulaglutide — DIARRHOEA

FDA adverse event reports for dulaglutide: DIARRHOEA reported 5737 times out of 101618 total reports (5.6%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datainjection_site_reaction10%

FDA FAERS — dulaglutide — INJECTION SITE PAIN

FDA adverse event reports for dulaglutide: INJECTION SITE PAIN reported 9796 times out of 101618 total reports (9.6%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datanausea10%

FDA FAERS — dulaglutide — NAUSEA

FDA adverse event reports for dulaglutide: NAUSEA reported 9986 times out of 101618 total reports (9.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=101618Extraction: high
Regulatory datadizziness3%

FDA FAERS — liraglutide — DIZZINESS

FDA adverse event reports for liraglutide: DIZZINESS reported 1517 times out of 51432 total reports (2.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=51432Extraction: high
Regulatory data3%

FDA FAERS — liraglutide — OFF LABEL USE

FDA adverse event reports for liraglutide: OFF LABEL USE reported 1761 times out of 51432 total reports (3.4%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=51432Extraction: high
Regulatory data6%

FDA FAERS — tirzepatide — OFF LABEL USE

FDA adverse event reports for tirzepatide: OFF LABEL USE reported 7726 times out of 140971 total reports (5.5%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/12/2026n=140971Extraction: high
User reportvomitingsevere

Reddit r/diabetes_t2 — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/diabetes_t2 — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportfatiguemoderate

Reddit r/diabetes_t2 — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportvomitingmoderate

Reddit r/diabetes_t2 — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportnauseamoderate

Reddit r/diabetes_t2 — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportvomitingsevere

Reddit r/diabetes_t2 — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/diabetes_t2 — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportvomitingsevere

Reddit r/diabetes_t2 — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highExtraction: high
User reportnauseasevere

Reddit r/diabetes_t2 — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highExtraction: high
User reportvomitingsevere

Reddit r/diabetes_t2 — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportabdominal_painsevere

Reddit r/diabetes_t2 — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportdiarrheasevere

Reddit r/diabetes_t2 — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportvomiting

Reddit r/diabetes — Dependence on Zepbound

Utterly random musings…. So today I haven’t felt right. Stomach is off and some other things. I am one of the lucky ones who has had almost no side effects from the start. Generally my digestive system is oh so much better with Zep and it was very bad before. For me it’s been almost all upside. Not bragging, just explaining my relationship to Zep. So of course because I am wired for ANXIETY in the back of my brain I have been all what if it’s the Zepbound and suddenly it have to stop taking

Collected: 4/10/2026Extraction: low
User reportnausea

Reddit r/diabetes — Dependence on Zepbound

Utterly random musings…. So today I haven’t felt right. Stomach is off and some other things. I am one of the lucky ones who has had almost no side effects from the start. Generally my digestive system is oh so much better with Zep and it was very bad before. For me it’s been almost all upside. Not bragging, just explaining my relationship to Zep. So of course because I am wired for ANXIETY in the back of my brain I have been all what if it’s the Zepbound and suddenly it have to stop taking

Collected: 4/10/2026Extraction: low
User reportreduced_appetite

Reddit r/diabetes — Super responder? To increase or to not increase

I recently started zep 3 weeks ago as of tomorrow. I will be taking my 4th dose tomorrow morning. I am 28f, and 5’8. I started at 318 pounds and as of today I am 291. I have been taking 2.5 and seeing some pretty good results. I know a lot of the weight lost in the beginning is inflammation, but I’ve been at a steady calorie deficit mainly eating protein and veggies. I also have made some huge life changes cutting out soda, processed sugars etc. I am currently also on my period so I’m assuming m

Collected: 4/10/2026Dose: lown=1Extraction: medium
User reportvomitingsevere

Reddit r/PCOS — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/PCOS — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportreduced_appetitemoderate

Reddit r/PCOS — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: medium
User reportfatiguemoderate

Reddit r/PCOS — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportvomitingmoderate

Reddit r/PCOS — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportnauseamoderate

Reddit r/PCOS — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportvomitingsevere

Reddit r/PCOS — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/PCOS — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportvomitingsevere

Reddit r/PCOS — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highExtraction: high
User reportnauseasevere

Reddit r/PCOS — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highExtraction: high
User reportvomitingsevere

Reddit r/PCOS — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportabdominal_painsevere

Reddit r/PCOS — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportdiarrheasevere

Reddit r/PCOS — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportvomiting

Reddit r/compoundedtirzepatide — Dependence on Zepbound

Utterly random musings…. So today I haven’t felt right. Stomach is off and some other things. I am one of the lucky ones who has had almost no side effects from the start. Generally my digestive system is oh so much better with Zep and it was very bad before. For me it’s been almost all upside. Not bragging, just explaining my relationship to Zep. So of course because I am wired for ANXIETY in the back of my brain I have been all what if it’s the Zepbound and suddenly it have to stop taking

Collected: 4/10/2026Extraction: low
User reportnausea

Reddit r/compoundedtirzepatide — Dependence on Zepbound

Utterly random musings…. So today I haven’t felt right. Stomach is off and some other things. I am one of the lucky ones who has had almost no side effects from the start. Generally my digestive system is oh so much better with Zep and it was very bad before. For me it’s been almost all upside. Not bragging, just explaining my relationship to Zep. So of course because I am wired for ANXIETY in the back of my brain I have been all what if it’s the Zepbound and suddenly it have to stop taking

Collected: 4/10/2026Extraction: low
User reportvomitingsevere

Reddit r/PeptideSource — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/PeptideSource — How long does withdrawal typically take for antipsychotics?

I was wondering if anyone had the same experience I am currently facing. I am 51 days off olanzapine (tapered off of in it 21 days cause I realized I had akathisia and it’s likely caused by olanzapine) and every day since getting off I have struggled with horrible nausea severe insomnia and akathisia (I had akathisia from day 1 on olanzapine as well). The symptoms had been pretty bad, consisting of at least one awful day once a week where my nausea would get severe. A week ago instead of my norm

Collected: 4/10/2026n=1Extraction: high
User reportreduced_appetitemoderate

Reddit r/PeptideSource — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: medium
User reportfatiguemoderate

Reddit r/PeptideSource — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportvomitingmoderate

Reddit r/PeptideSource — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportnauseamoderate

Reddit r/PeptideSource — The nausea is wearing me out

I'm 13w5d and for some reason the nausea seems to be worse than just a couple weeks ago. He's vetoing food he was fine with before, and I can't brush my teeth without vomiting. Last couple days have been a struggle bus, and I still got 3 more weeks of teaching. My energy tank is running on empty. Tell me it settles back down. Please.

Collected: 4/10/2026Extraction: high
User reportacid_reflux

Reddit r/PeptideSource — Unstoppable Diarrhea pup. Advice/Suggestions desperately needed

Hello all, I have a sweet 9 month old golden pup who randomly got sick last Saturday. Threw up his entire lunch on the couch followed by multiple vomiting episodes of bile along with diarrhea all over the place. We took him to the vet where they put him on IVs for a few hours while they ran blood tests and X-rays. All of it came back negative so they sent us home with nausea and acid reflux meds and asked us to return if things get worse. Over the next 3 days, his vomiting completely stopped bu

Collected: 4/10/2026Extraction: medium
User reportnausea

Reddit r/PeptideSource — Unstoppable Diarrhea pup. Advice/Suggestions desperately needed

Hello all, I have a sweet 9 month old golden pup who randomly got sick last Saturday. Threw up his entire lunch on the couch followed by multiple vomiting episodes of bile along with diarrhea all over the place. We took him to the vet where they put him on IVs for a few hours while they ran blood tests and X-rays. All of it came back negative so they sent us home with nausea and acid reflux meds and asked us to return if things get worse. Over the next 3 days, his vomiting completely stopped bu

Collected: 4/10/2026Extraction: medium
User reportdiarrheamoderate

Reddit r/PeptideSource — Unstoppable Diarrhea pup. Advice/Suggestions desperately needed

Hello all, I have a sweet 9 month old golden pup who randomly got sick last Saturday. Threw up his entire lunch on the couch followed by multiple vomiting episodes of bile along with diarrhea all over the place. We took him to the vet where they put him on IVs for a few hours while they ran blood tests and X-rays. All of it came back negative so they sent us home with nausea and acid reflux meds and asked us to return if things get worse. Over the next 3 days, his vomiting completely stopped bu

Collected: 4/10/2026Extraction: high
User reportvomitingmoderate

Reddit r/PeptideSource — Unstoppable Diarrhea pup. Advice/Suggestions desperately needed

Hello all, I have a sweet 9 month old golden pup who randomly got sick last Saturday. Threw up his entire lunch on the couch followed by multiple vomiting episodes of bile along with diarrhea all over the place. We took him to the vet where they put him on IVs for a few hours while they ran blood tests and X-rays. All of it came back negative so they sent us home with nausea and acid reflux meds and asked us to return if things get worse. Over the next 3 days, his vomiting completely stopped bu

Collected: 4/10/2026Extraction: high
User reportvomitingsevere

Reddit r/PeptideSource — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportnauseasevere

Reddit r/PeptideSource — Results are weird?

So I’ve been on semaglutide for one year in July. I’ve lost almost 100 pounds. I had horrible side effects with nausea and vomiting that significantly impacted what I was able to keep down. I feel like I’ve lost a huge amount of weight pound wise, but size wise? I dropped a couple sizes but don’t feel like I’m anywhere near where I should be. I’m 5 foot 7 so I would think you would look at me and see a profound difference. I was stupid and I never took before pictures so I don’t have anything to

Collected: 4/10/2026n=1Extraction: high
User reportvomitingsevere

Reddit r/PeptideSource — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highn=1Extraction: high
User reportnauseasevere

Reddit r/PeptideSource — Restarted Wegovy at 1.7 after 2.5 months off… brutal nausea/vomiting – anyone el

A couple months ago I was on Wegovy and titrated from 0.25 up to 2.0 with zero side effects. Then I had to stop for about 2.5 months. My doctor restarted me at 1.7 mg, and about 2 hours after the injection I got intense nausea and ended up vomiting everything in my stomach. I’ve felt pretty awful since then (now \~36 hours later). Went to urgent care, got anti-nausea meds which are helping. I’m slowly sipping Pedialyte and just started eating crackers — first food/liquids since it started. Ha

Collected: 4/10/2026Dose: highn=1Extraction: high
User reportvomitingsevere

Reddit r/PeptideSource — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportabdominal_painsevere

Reddit r/PeptideSource — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
User reportdiarrheasevere

Reddit r/PeptideSource — never sleeping due to emetophobia

okay i need advice on how to get over this and also just stories if anyone feels the same way. basically in 2024 i went to bali after i graduated. the whole trip i felt off with my stomach and 2 days after i was home it happened. i awoke with the worst stomach pain i have ever felt in my life and had diarrhoea all day. i began dry heaving and ended up being sick once into the bath tub (and legit pooped myself at the same time) all while my dad was yelling at me when he was supposed to be helpin

Collected: 4/10/2026Extraction: high
Clinical studynausea

PubMed — Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.

1. N Engl J Med. 2023 Aug 10;389(6):514-526. doi: 10.1056/NEJMoa2301972. Epub 2023 Jun 26. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. Jastreboff AM(1), Kaplan LM(1), Frías JP(1), Wu Q(1), Du Y(1), Gurbuz S(1), Coskun T(1), Haupt A(1), Milicevic Z(1), Hartman ML(1); Retatrutide Phase 2 Obesity Trial Investigators. Collaborators: Fatakia A, Davidson E, Brian S, Hsia S, Haggag A, Rosenstock J, Frias J, Kessler A, Widicus D, Bacchelli S, Barnes C, Sheikh-Ali M,

Collected: 4/10/2026Extraction: low
Clinical studynausea

PubMed — 10.1016/j.jcte.2024.100333. eCollection 2024 Mar.

J Clin Transl Endocrinol. 2024 Feb 29;35:100333. doi: 10.1016/j.jcte.2024.100333. eCollection 2024 Mar. GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)? A systematic review. Aoun L(1), Almardini S(1), Saliba F(1), Haddadin F(1), Mourad O(1), Jdaidani J(1), Morcos Z(1), Al Saidi I(1), Bou Sanayeh E(1), Saliba S(2), Almardini M(3), Zaidan J(4). Author information: (1)Department of Internal Medicine, Staten Island University Hospi

Collected: 4/10/2026Extraction: low
Clinical studynausea

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Collected: 4/10/2026Extraction: low
Clinical studynausea

PubMed — Once-Weekly Semaglutide in Adults with Overweight or Obesity.

1. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10. Once-Weekly Semaglutide in Adults with Overweight or Obesity. Wilding JPH(1), Batterham RL(1), Calanna S(1), Davies M(1), Van Gaal LF(1), Lingvay I(1), McGowan BM(1), Rosenstock J(1), Tran MTD(1), Wadden TA(1), Wharton S(1), Yokote K(1), Zeuthen N(1), Kushner RF(1); STEP 1 Study Group. Collaborators: Ackermann MA, Luquez C, Mayer M, Musso C, Salzberg S, Colin I, Mertens A, Scheen A, Thissen JP, Ga

Collected: 4/10/2026Extraction: low
User reportabdominal_painmild

Reddit r/diabetes_t2 — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: medium
User reportacid_refluxmoderate

Reddit r/diabetes_t2 — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportdiarrheamoderate

Reddit r/diabetes_t2 — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/diabetes_t2 — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportreduced_appetite

Reddit r/diabetes_t2 — For all the newbies in this sub

​ I’m honestly getting a little scared seeing how GLP-1 drugs (Semaglutide / Tirzepatide) are being thrown around so casually now, especially for people with normal BMI who just want to drop a few kilos. The worst part is watching how it’s being sold to brides-to-be like it’s some quick fix before the wedding. It’s not. This is literally a Schedule H drug. It’s not meant to be taken like a supplement. I’ve been on it for almost 6 months now, and yes, it has helped me a lot. I have P

Collected: 4/9/2026Extraction: high
User reportdiarrheasevere

Reddit r/diabetes_t2 — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026Extraction: high
User reportconstipationmild

Reddit r/diabetes_t2 — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026Extraction: high
User reportacid_reflux

Reddit r/diabetes_t2 — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/diabetes_t2 — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportabdominal_painmild

Reddit r/diabetes_t2 — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026n=1Extraction: high
User reportconstipationmild

Reddit r/diabetes_t2 — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026n=1Extraction: high
User reportheadache

Reddit r/diabetes — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026n=1Extraction: medium
User reportconstipation

Reddit r/diabetes — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026n=1Extraction: medium
User reportvomitingmoderate

Reddit r/diabetes — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026Dose: mediumn=1Extraction: high
User reportdiarrheamoderate

Reddit r/diabetes — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026Dose: mediumn=1Extraction: high
User reportabdominal_pain

Reddit r/diabetes — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: high
User reportfatigue

Reddit r/diabetes — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: medium
User reportconstipation

Reddit r/diabetes — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: high
User reportfatigue

Reddit r/diabetes — Anyone have a polyp cause symptoms?

A few years ago I had sludge and small stones seen on MRCP and MRI, now they can only see one 4mm polyp in the neck of the gallbladder which they don’t think is causing my symptoms. HIDA scan 69%. Has anyone ever had stones and sludge just disappear? Has anyone ever been able to have their gallbladder removed just from a small polyp and found that they felt better afterward? I also was recently diagnosed with severe exocrine pancreatic insufficiency and thought maybe the stones could have moved

Collected: 4/9/2026Extraction: medium
User reportacid_reflux

Reddit r/diabetes — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/diabetes — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportgallstonesmoderate

Reddit r/diabetes — High calorie safe foods

Greetings gallbladder gang! I’m still waiting on confirmation of my diagnosis but my doctor suspects I have gallstones. I’ve had two gallbladder attacks in the last three days and I’m a little scared to eat anything at the moment. The problem with that is I’m currently breastfeeding and need to make sure I’m eating enough to get me through my work day and to keep up my supply. I understand everyone’s bodies are different and may have different triggers, but I’m just wondering what your favou

Collected: 4/9/2026Extraction: high
User reportgallstones

Reddit r/diabetes — So happy

Today I got a 15.8% raise (no promo) I work @ MANGA Have been going through really difficult stuff \- got gallbladder removed 6 months ago \- got cleared out 1 month ago of olanzapine and psychiatric meds after 5 years \- 2 years since the last time I was commited into a psychiatric hospital for the last times \- 5 years since being disowned \- 5 years since being expelled from college \-3 years with stable housing Really happy

Collected: 4/9/2026Extraction: low
User reportgallstonessevere

Reddit r/diabetes — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: medium
User reportabdominal_painsevere

Reddit r/diabetes — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: high
User reportreduced_appetitemild

Reddit r/diabetes — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: high
User reportnauseamild

Reddit r/PCOS — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: medium
User reportacid_refluxmoderate

Reddit r/PCOS — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportdiarrheamoderate

Reddit r/PCOS — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/PCOS — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportreduced_appetitemoderate

Reddit r/PCOS — For all the newbies in this sub

​ I’m honestly getting a little scared seeing how GLP-1 drugs (Semaglutide / Tirzepatide) are being thrown around so casually now, especially for people with normal BMI who just want to drop a few kilos. The worst part is watching how it’s being sold to brides-to-be like it’s some quick fix before the wedding. It’s not. This is literally a Schedule H drug. It’s not meant to be taken like a supplement. I’ve been on it for almost 6 months now, and yes, it has helped me a lot. I have P

Collected: 4/9/2026Extraction: high
User reportdiarrheasevere

Reddit r/PCOS — Newly diagnosedvin march with a recurrence

39 yr old female. I was diagnosed with diverticulitis in the ER on 3/6. i was discharged with cipro and flagyl. I ended up getting thrush because of the antibiotics and had to get magic mouthwash to clear it up. I came to this sub bc my hospital D/C instructions were shit. I followed the 3 day liquid diet then moved to low residue. after about 1.5 weeks i started reintroducing fiber. I took it slow just adding a new food daily and then more fiber overtime. i had no pain dueing this time and last

Collected: 4/9/2026Extraction: high
User reportdiarrheasevere

Reddit r/PCOS — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026n=1Extraction: high
User reportconstipationmild

Reddit r/PCOS — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026n=1Extraction: high
User reportacid_reflux

Reddit r/PCOS — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/PCOS — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportabdominal_painmild

Reddit r/PCOS — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026Extraction: high
User reportconstipationmild

Reddit r/PCOS — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026Extraction: high
User reportgallstonessevere

Reddit r/compoundedtirzepatide — Real Face of Living Prophet Jesus Christ Kalki Kriva Dna Print

Asalamualaikum Everyone, I’m currently going through a difficult phase. I was recently hospitalized due to a serious gallbladder condition and will need surgery soon. Medical expenses have been overwhelming, and I’m trying my best to manage things while also taking care of my elderly parents. (Can chk details on my profile) If this artwork resonates with you, you can support me by purchasing a print of Prophet Jesus. Jazakallah

Collected: 4/9/2026Extraction: low
User reportheadache

Reddit r/compoundedtirzepatide — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026n=1Extraction: medium
User reportconstipation

Reddit r/compoundedtirzepatide — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026n=1Extraction: medium
User reportvomitingmoderate

Reddit r/compoundedtirzepatide — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026Dose: mediumn=1Extraction: high
User reportdiarrheamoderate

Reddit r/compoundedtirzepatide — Fed up of D&V

I've always been sensitive to side effects usually constipation and headaches. My dose day is Saturday and 2 weeks ago I took 7.5mg for the first time (upped from 6.25mg). The following Monday I had D&V. Both my kids had it over the weekend first so assumed it was a bug. Did my 2nd dose of 7.5mg, both kids and husband ill at weekend and then I had D&V again on Monday. Unlucky I thought, struggling to shake it as a family apparently. It's now Thursday morning and I've started with D&a

Collected: 4/9/2026Dose: mediumn=1Extraction: high
User reportfatigue

Reddit r/compoundedtirzepatide — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: medium
User reportabdominal_pain

Reddit r/compoundedtirzepatide — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/compoundedtirzepatide — I’m so lost and exhausted 🫩

I’ve made a few posts before saying that medroxyprogesterone (Provera) pills made my sciatica, joint pain, and RLS significantly worse. Well…I’ve been off of Provera for a week now and I’m having a horrible endo flare. Not the worst I’ve had, but muscle spasms in my abdomen and vaginal canal, constipation, and endo belly. Has anyone had experience being off of Provera for a while? Did these symptoms balance out or no? I didn’t have my Provera for about a month and didn’t have an endo flare but

Collected: 4/9/2026Extraction: high
User reportfatigue

Reddit r/compoundedtirzepatide — Anyone have a polyp cause symptoms?

A few years ago I had sludge and small stones seen on MRCP and MRI, now they can only see one 4mm polyp in the neck of the gallbladder which they don’t think is causing my symptoms. HIDA scan 69%. Has anyone ever had stones and sludge just disappear? Has anyone ever been able to have their gallbladder removed just from a small polyp and found that they felt better afterward? I also was recently diagnosed with severe exocrine pancreatic insufficiency and thought maybe the stones could have moved

Collected: 4/9/2026Extraction: medium
User reportpancreatitissevere

Reddit r/compoundedtirzepatide — Anyone have a polyp cause symptoms?

A few years ago I had sludge and small stones seen on MRCP and MRI, now they can only see one 4mm polyp in the neck of the gallbladder which they don’t think is causing my symptoms. HIDA scan 69%. Has anyone ever had stones and sludge just disappear? Has anyone ever been able to have their gallbladder removed just from a small polyp and found that they felt better afterward? I also was recently diagnosed with severe exocrine pancreatic insufficiency and thought maybe the stones could have moved

Collected: 4/9/2026Extraction: high
User reportgallstones

Reddit r/compoundedtirzepatide — Anyone have a polyp cause symptoms?

A few years ago I had sludge and small stones seen on MRCP and MRI, now they can only see one 4mm polyp in the neck of the gallbladder which they don’t think is causing my symptoms. HIDA scan 69%. Has anyone ever had stones and sludge just disappear? Has anyone ever been able to have their gallbladder removed just from a small polyp and found that they felt better afterward? I also was recently diagnosed with severe exocrine pancreatic insufficiency and thought maybe the stones could have moved

Collected: 4/9/2026Extraction: high
User reportacid_reflux

Reddit r/compoundedtirzepatide — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/compoundedtirzepatide — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportgallstonesmoderate

Reddit r/compoundedtirzepatide — High calorie safe foods

Greetings gallbladder gang! I’m still waiting on confirmation of my diagnosis but my doctor suspects I have gallstones. I’ve had two gallbladder attacks in the last three days and I’m a little scared to eat anything at the moment. The problem with that is I’m currently breastfeeding and need to make sure I’m eating enough to get me through my work day and to keep up my supply. I understand everyone’s bodies are different and may have different triggers, but I’m just wondering what your favou

Collected: 4/9/2026Extraction: high
User reportgallstones

Reddit r/compoundedtirzepatide — So happy

Today I got a 15.8% raise (no promo) I work @ MANGA Have been going through really difficult stuff \- got gallbladder removed 6 months ago \- got cleared out 1 month ago of olanzapine and psychiatric meds after 5 years \- 2 years since the last time I was commited into a psychiatric hospital for the last times \- 5 years since being disowned \- 5 years since being expelled from college \-3 years with stable housing Really happy

Collected: 4/9/2026Extraction: low
User reportgallstonessevere

Reddit r/compoundedtirzepatide — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: medium
User reportabdominal_painsevere

Reddit r/compoundedtirzepatide — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: high
User reportreduced_appetitemild

Reddit r/compoundedtirzepatide — Semaglutide

Hello. I (21F) started taking Semaglutide through Remedy Meds early 2025. I lost approximately 30 pounds relatively quickly (not too fast though) and my side effects were very mild, but I couldn’t afford the $300 a month anymore. I cancelled the membership and switched to Mochi Health. With Mochi there was no appetite reduction and my side effects were absolutely horrible. I would get the WORST gas pain which I could barely handle. Eventually I went to the hospital for this gas pain; turned out

Collected: 4/9/2026n=1Extraction: high
User reportvomitingmild

Reddit r/PeptideSource — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: medium
User reportacid_refluxmoderate

Reddit r/PeptideSource — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportdiarrheamoderate

Reddit r/PeptideSource — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportconstipationmoderate

Reddit r/PeptideSource — 3 years post GB removal and I’m having some issues .

I had my GB out three years ago . I have had “ IBS “ for years and recently I feel like things have gotten worse . I will go days with out pooping and then when I do I’m either constipated or have the runs . More times than not it’s yellow and a bran flake consistency . For the past week I’ve been going a lot !!! It’s the bran flake , yellow , urgent few times a day kinda flare im in . I also had what u believe to be heartburn recently that nothing will touch . I’m super gassy during this . Put

Collected: 4/9/2026n=1Extraction: high
User reportreduced_appetite

Reddit r/PeptideSource — For all the newbies in this sub

​ I’m honestly getting a little scared seeing how GLP-1 drugs (Semaglutide / Tirzepatide) are being thrown around so casually now, especially for people with normal BMI who just want to drop a few kilos. The worst part is watching how it’s being sold to brides-to-be like it’s some quick fix before the wedding. It’s not. This is literally a Schedule H drug. It’s not meant to be taken like a supplement. I’ve been on it for almost 6 months now, and yes, it has helped me a lot. I have P

Collected: 4/9/2026Extraction: high
User reportdiarrheasevere

Reddit r/PeptideSource — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026Extraction: high
User reportconstipationmild

Reddit r/PeptideSource — Post Chemo GI Issues?

I had 6 carbo/taxol infusions, last infusion 2/11. I coasted through chemo, relatively speaking. However, I did have constipation that became more persistent with each cycle. By cycle 4, I was constipated through the entire cycle and not just for a few days. It was not severe, but I’d describe it as sluggish digestion that required stool softeners to manage. Post-chemo, my constipation continued until a couple of weeks ago. At that point I started having watery, extremely urgent diarrhea inter

Collected: 4/9/2026Extraction: high
User reportacid_reflux

Reddit r/PeptideSource — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportconstipation

Reddit r/PeptideSource — To do surgery or not to do surgery

Hi all! So my surgery is scheduled for 4/13 and I'm getting cold feet :( I've had a 3 year history of IBS (constipation, oily/discolored stools, reflux, etc). I was wondering if anybody had insight or advice on what I should do. It started with SIBO caused by intermittent fasting, but I recently had a GI map done while not taking any digestive enzymes or supplements that confirmed that it's good and gone! No parasites or bacteria imbalance either, my dr was surprised. Basically, I have severe i

Collected: 4/9/2026Extraction: high
User reportabdominal_painmild

Reddit r/PeptideSource — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026Extraction: high
User reportconstipationmild

Reddit r/PeptideSource — Positive Anti-DGP IgA, Negative tTG IgA– False positive?

I got a blood test done because I was having consipation (3-4 days w/o bowel movements) and some abdominal pain (which I'm pretty sure was from the constipation). My doctor requested labs, and they came back with a Positive Anti-DGP IgA, but a Negative tTG IgA. I do not really have the symptoms of celiac, no weightloss, no diarrhea, no bloating (beyond the normal gas), no vomiting, etc. Is there a chance it's a false positive, especially because the tTG IgA came back negative, and it's conside

Collected: 4/9/2026Extraction: high
Regulatory datanausea50%

FDA FAERS — orforglipron — NAUSEA

FDA adverse event reports for orforglipron: NAUSEA reported 1 times out of 2 total reports (50.0%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=2Extraction: high
Regulatory dataacid_reflux50%

FDA FAERS — orforglipron — DYSPEPSIA

FDA adverse event reports for orforglipron: DYSPEPSIA reported 1 times out of 2 total reports (50.0%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=2Extraction: high
Regulatory dataabdominal_pain3%

FDA FAERS — liraglutide — ABDOMINAL PAIN UPPER

FDA adverse event reports for liraglutide: ABDOMINAL PAIN UPPER reported 1425 times out of 51432 total reports (2.8%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=51432Extraction: high
Regulatory dataconstipation3%

FDA FAERS — liraglutide — CONSTIPATION

FDA adverse event reports for liraglutide: CONSTIPATION reported 1515 times out of 51432 total reports (2.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=51432Extraction: high
Regulatory datafatigue2%

FDA FAERS — tirzepatide — FATIGUE

FDA adverse event reports for tirzepatide: FATIGUE reported 3179 times out of 140971 total reports (2.3%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=140971Extraction: high
Regulatory dataconstipation3%

FDA FAERS — tirzepatide — CONSTIPATION

FDA adverse event reports for tirzepatide: CONSTIPATION reported 4190 times out of 140971 total reports (3.0%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=140971Extraction: high
Regulatory datadizziness3%

FDA FAERS — semaglutide — DIZZINESS

FDA adverse event reports for semaglutide: DIZZINESS reported 2874 times out of 99460 total reports (2.9%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=99460Extraction: high
Regulatory dataabdominal_pain3%

FDA FAERS — semaglutide — ABDOMINAL PAIN UPPER

FDA adverse event reports for semaglutide: ABDOMINAL PAIN UPPER reported 2951 times out of 99460 total reports (3.0%). Source: FDA FAERS database. Note: FAERS data represents reported events, not incidence rates. Demographics may vary.

Collected: 4/8/2026n=99460Extraction: high
User reportabdominal_pain

Reddit r/diabetes_t2 — Gastrointestinal Distress, Hot Showers and Vasovagal Syncope

Age 38 Sex M Height 6'2" / 188cm Weight 210 lbs / 95.5 kg Race Caucasian Duration of complaint 5-10 minutes Location at home, Oregon, USA Any existing relevant medical issues N/A Current medications Omeprazole 40mg daily Hi all, hope to get some opinions here. I had this happen twice now about 3.5 years apart, with the lead in being nearly identical. Outcomes differed marginally, primarily due to my recognition of what was happening the second time. Both times I've had some sort of ga

Collected: 4/8/2026n=1Extraction: medium
User reporthair_loss

Reddit r/diabetes — Medication and supplement recs if minoxidil didn't work for you?

I took prescribed oral minoxidil and spironolactone for a year and a couple of months with no improvement. At this point I just want to take supplements to prevent hair loss if not hair growth. If oral minoxidil and spironolactone did not work for you, what medication, suplement and/or treatment did? My hairline is redonk-ulously high already naturally, I need to keep what I can fr lol (I'm diagnosed with androgenetic alopecia)

Collected: 4/8/2026Extraction: high
User reportabdominal_painmild

Reddit r/diabetes — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportreduced_appetite

Reddit r/diabetes — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportnauseamild

Reddit r/diabetes — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportfatiguemild

Reddit r/PCOS — Gastrointestinal Distress, Hot Showers and Vasovagal Syncope

Age 38 Sex M Height 6'2" / 188cm Weight 210 lbs / 95.5 kg Race Caucasian Duration of complaint 5-10 minutes Location at home, Oregon, USA Any existing relevant medical issues N/A Current medications Omeprazole 40mg daily Hi all, hope to get some opinions here. I had this happen twice now about 3.5 years apart, with the lead in being nearly identical. Outcomes differed marginally, primarily due to my recognition of what was happening the second time. Both times I've had some sort of ga

Collected: 4/8/2026n=1Extraction: medium
User reportabdominal_pain

Reddit r/PCOS — Gastrointestinal Distress, Hot Showers and Vasovagal Syncope

Age 38 Sex M Height 6'2" / 188cm Weight 210 lbs / 95.5 kg Race Caucasian Duration of complaint 5-10 minutes Location at home, Oregon, USA Any existing relevant medical issues N/A Current medications Omeprazole 40mg daily Hi all, hope to get some opinions here. I had this happen twice now about 3.5 years apart, with the lead in being nearly identical. Outcomes differed marginally, primarily due to my recognition of what was happening the second time. Both times I've had some sort of ga

Collected: 4/8/2026n=1Extraction: high
User reporthair_loss

Reddit r/compoundedtirzepatide — I'm so tired of fighting with my brain

I've been struggling a lot lately with worries of losing hair or teeth. I'm constantly looking up gum recession and hair loss, comparing it to my own hair and teeth. It's becoming a major stressor for me. I know I'm probably not losing either, but the What Ifs keep running through my mind. I'm so sick of it. It reminds me of before where I spent weeks worried I had lice or bed bugs. I assumed all the little bumps on my legs or itches of my head were some kind of bug eating away at me. It's so an

Collected: 4/8/2026Extraction: low
User reportabdominal_painmoderate

Reddit r/compoundedtirzepatide — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportreduced_appetite

Reddit r/compoundedtirzepatide — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportnauseamild

Reddit r/compoundedtirzepatide — Periods every two months- no answers

One year ago my period suddenly became irregular. I’m 22 years old (Female), weigh 140 lbs, and I'm 5'8. I’ve always had painful periods and issues with that. Those issues remain, only now they happen when I’m not bleeding too. On average based on charting my symptoms, I feel mildly to pretty badly ill for half a month, every month whether I bleed or not. I experience cramps, nausea, lower back pain, vaginal soreness, leg pain, loss of appetite, general sense of dying bc I'm dramatic, and gettin

Collected: 4/8/2026n=1Extraction: high
User reportfatiguemild

Reddit r/PeptideSource — Gastrointestinal Distress, Hot Showers and Vasovagal Syncope

Age 38 Sex M Height 6'2" / 188cm Weight 210 lbs / 95.5 kg Race Caucasian Duration of complaint 5-10 minutes Location at home, Oregon, USA Any existing relevant medical issues N/A Current medications Omeprazole 40mg daily Hi all, hope to get some opinions here. I had this happen twice now about 3.5 years apart, with the lead in being nearly identical. Outcomes differed marginally, primarily due to my recognition of what was happening the second time. Both times I've had some sort of ga

Collected: 4/8/2026n=1Extraction: medium
User reportabdominal_pain

Reddit r/PeptideSource — Gastrointestinal Distress, Hot Showers and Vasovagal Syncope

Age 38 Sex M Height 6'2" / 188cm Weight 210 lbs / 95.5 kg Race Caucasian Duration of complaint 5-10 minutes Location at home, Oregon, USA Any existing relevant medical issues N/A Current medications Omeprazole 40mg daily Hi all, hope to get some opinions here. I had this happen twice now about 3.5 years apart, with the lead in being nearly identical. Outcomes differed marginally, primarily due to my recognition of what was happening the second time. Both times I've had some sort of ga

Collected: 4/8/2026n=1Extraction: medium
Clinical studynausea

PubMed — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity.

1. N Engl J Med. 2025 Jan 30;392(5):427-437. doi: 10.1056/NEJMoa2410027. Epub 2024 Nov 16. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. Packer M(1), Zile MR(1), Kramer CM(1), Baum SJ(1), Litwin SE(1), Menon V(1), Ge J(1), Weerakkody GJ(1), Ou Y(1), Bunck MC(1), Hurt KC(1), Murakami M(1), Borlaug BA(1); SUMMIT Trial Study Group. Collaborators: Cosman C, Majul C, Resk J, Sassone S, Sarem M, Chirino Navarta D, Montaña O, Vallejos J, Wenetz LMM, Albisu Di Gennar

Collected: 4/8/2026Extraction: low
Clinical studyconstipation

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Collected: 4/8/2026Extraction: low
Clinical studydiarrhea

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Collected: 4/8/2026Extraction: low
Clinical studyvomiting

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Collected: 4/8/2026Extraction: low
Clinical studynausea

PubMed — Tirzepatide for Obesity Treatment and Diabetes Prevention.

N Engl J Med. 2025 Mar 6;392(10):958-971. doi: 10.1056/NEJMoa2410819. Epub 2024 Nov 13. Tirzepatide for Obesity Treatment and Diabetes Prevention. Jastreboff AM(1)(2), le Roux CW(3), Stefanski A(4), Aronne LJ(5), Halpern B(6), Wharton S(7)(8), Wilding JPH(9), Perreault L(10), Zhang S(4), Battula R(4), Bunck MC(4), Ahmad NN(4), Jouravskaya I(4); SURMOUNT-1 Investigators. Collaborators: Connery L, Tran H, Blevins T, Gangi S, Welch M, Nunez L, Shea H, Bhargava A, Kutner M, Nardandrea J, Will

Collected: 4/8/2026Extraction: low
Regulatory datafatigue4%

FDA FAERS — liraglutide — FATIGUE

FDA adverse event reports for liraglutide: FATIGUE reported 1656 times out of 43057 total reports (3.8%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory dataheadache5%

FDA FAERS — liraglutide — HEADACHE

FDA adverse event reports for liraglutide: HEADACHE reported 2018 times out of 43057 total reports (4.7%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datareduced_appetite5%

FDA FAERS — liraglutide — DECREASED APPETITE

FDA adverse event reports for liraglutide: DECREASED APPETITE reported 2113 times out of 43057 total reports (4.9%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datapancreatitis5%

FDA FAERS — liraglutide — PANCREATITIS

FDA adverse event reports for liraglutide: PANCREATITIS reported 2343 times out of 43057 total reports (5.4%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datadiarrhea8%

FDA FAERS — liraglutide — DIARRHOEA

FDA adverse event reports for liraglutide: DIARRHOEA reported 3345 times out of 43057 total reports (7.8%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datavomiting8%

FDA FAERS — liraglutide — VOMITING

FDA adverse event reports for liraglutide: VOMITING reported 3447 times out of 43057 total reports (8.0%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datanausea17%

FDA FAERS — liraglutide — NAUSEA

FDA adverse event reports for liraglutide: NAUSEA reported 7118 times out of 43057 total reports (16.5%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=43057Extraction: high
Regulatory datainjection_site_reaction4%

FDA FAERS — tirzepatide — INJECTION SITE ERYTHEMA

FDA adverse event reports for tirzepatide: INJECTION SITE ERYTHEMA reported 4295 times out of 122084 total reports (3.5%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory datainjection_site_reaction4%

FDA FAERS — tirzepatide — INJECTION SITE HAEMORRHAGE

FDA adverse event reports for tirzepatide: INJECTION SITE HAEMORRHAGE reported 4746 times out of 122084 total reports (3.9%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory datavomiting5%

FDA FAERS — tirzepatide — VOMITING

FDA adverse event reports for tirzepatide: VOMITING reported 5685 times out of 122084 total reports (4.7%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory datadiarrhea6%

FDA FAERS — tirzepatide — DIARRHOEA

FDA adverse event reports for tirzepatide: DIARRHOEA reported 6720 times out of 122084 total reports (5.5%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory datanausea10%

FDA FAERS — tirzepatide — NAUSEA

FDA adverse event reports for tirzepatide: NAUSEA reported 12028 times out of 122084 total reports (9.9%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory datainjection_site_reaction10%

FDA FAERS — tirzepatide — INJECTION SITE PAIN

FDA adverse event reports for tirzepatide: INJECTION SITE PAIN reported 12325 times out of 122084 total reports (10.1%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=122084Extraction: high
Regulatory dataheadache4%

FDA FAERS — semaglutide — HEADACHE

FDA adverse event reports for semaglutide: HEADACHE reported 3420 times out of 82377 total reports (4.2%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory datafatigue4%

FDA FAERS — semaglutide — FATIGUE

FDA adverse event reports for semaglutide: FATIGUE reported 3563 times out of 82377 total reports (4.3%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory dataconstipation6%

FDA FAERS — semaglutide — CONSTIPATION

FDA adverse event reports for semaglutide: CONSTIPATION reported 4612 times out of 82377 total reports (5.6%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory datareduced_appetite6%

FDA FAERS — semaglutide — DECREASED APPETITE

FDA adverse event reports for semaglutide: DECREASED APPETITE reported 4790 times out of 82377 total reports (5.8%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory datadiarrhea8%

FDA FAERS — semaglutide — DIARRHOEA

FDA adverse event reports for semaglutide: DIARRHOEA reported 6516 times out of 82377 total reports (7.9%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory datavomiting9%

FDA FAERS — semaglutide — VOMITING

FDA adverse event reports for semaglutide: VOMITING reported 7479 times out of 82377 total reports (9.1%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
Regulatory datanausea14%

FDA FAERS — semaglutide — NAUSEA

FDA adverse event reports for semaglutide: NAUSEA reported 11506 times out of 82377 total reports (14.0%). Note: FAERS data represents reported events, not incidence rates.

Collected: 4/7/2026n=82377Extraction: high
User reportvomitingmild

Reddit r/Zepbound — Throwing up occasionally but consistently

Ive been on the shots for about five months now and overall I really don’t have many bad side effects. Something that has been happening to me since \~before\~ I started Wegovy, but has kind of picked up a bit more since starting Wegovy, is that occasionally I will puke first thing in the morning. Especially if I’ve eaten too much the night before and went right to bed - I just kind of throw up that undigested food the next morning. However I just got back from a dinner where I had a few diff

Collected: 4/7/2026Extraction: high
User reportvomitingmild

Reddit r/Ozempic — Throwing up occasionally but consistently

Ive been on the shots for about five months now and overall I really don’t have many bad side effects. Something that has been happening to me since \~before\~ I started Wegovy, but has kind of picked up a bit more since starting Wegovy, is that occasionally I will puke first thing in the morning. Especially if I’ve eaten too much the night before and went right to bed - I just kind of throw up that undigested food the next morning. However I just got back from a dinner where I had a few diff

Collected: 4/7/2026n=1Extraction: high
User reportvomitingmild

Reddit r/loseit — Throwing up occasionally but consistently

Ive been on the shots for about five months now and overall I really don’t have many bad side effects. Something that has been happening to me since \~before\~ I started Wegovy, but has kind of picked up a bit more since starting Wegovy, is that occasionally I will puke first thing in the morning. Especially if I’ve eaten too much the night before and went right to bed - I just kind of throw up that undigested food the next morning. However I just got back from a dinner where I had a few diff

Collected: 4/7/2026Extraction: high
User reportvomitingmild

Reddit r/Mounjaro — Throwing up occasionally but consistently

Ive been on the shots for about five months now and overall I really don’t have many bad side effects. Something that has been happening to me since \~before\~ I started Wegovy, but has kind of picked up a bit more since starting Wegovy, is that occasionally I will puke first thing in the morning. Especially if I’ve eaten too much the night before and went right to bed - I just kind of throw up that undigested food the next morning. However I just got back from a dinner where I had a few diff

Collected: 4/7/2026Extraction: high
News sourceemotional_bluntingmoderate

BritBrief — Retatrutide emotional side effects report

Retatrutide weight loss drug linked to emotional side effects in users. Reports of reduced capacity for emotional engagement, particularly in romantic relationships. Described as feelings of detachment and diminished connection.

Collected: 4/6/2026Extraction: low
News sourceemotional_bluntingmoderate

The Guardian — Retatrutide emotional side effects (Apr 2026)

Retatrutide (triple-agonist GLP-1/GIP/glucagon) linked to emotional blunting and reduced romantic feelings. Users report detachment, diminished emotional connection. Not yet in official safety profile. Health experts calling for more studies on emotional/psychological side effects.

Collected: 4/6/2026Extraction: medium
User reportfatigue25%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Fatigue / Low energy: 25%. Commonly reported but often linked to eating significantly less. Your body is adjusting to lower caloric intake. Users say it improves after 2-3 weeks.

Collected: 4/6/2026Extraction: medium
News sourcefatigue14%mild

British Journal of Pharmacology warning (2024)

Fatigue / Low energy: clinical rate of 14% at high dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourcefatigue10%mild

British Journal of Pharmacology warning (2024)

Fatigue / Low energy: clinical rate of 10% at medium dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourcefatigue6%mild

British Journal of Pharmacology warning (2024)

Fatigue / Low energy: clinical rate of 6% at low dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportfatigue14%mild

Reddit & Weegclub NL user discussions (2024-2026)

Fatigue / Low energy: clinical rate of 14% at high dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportfatigue10%mild

Reddit & Weegclub NL user discussions (2024-2026)

Fatigue / Low energy: clinical rate of 10% at medium dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportfatigue6%mild

Reddit & Weegclub NL user discussions (2024-2026)

Fatigue / Low energy: clinical rate of 6% at low dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studyfatigue14%mild

Real-world evidence review (PMC 2025)

Fatigue / Low energy: clinical rate of 14% at high dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studyfatigue10%mild

Real-world evidence review (PMC 2025)

Fatigue / Low energy: clinical rate of 10% at medium dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studyfatigue6%mild

Real-world evidence review (PMC 2025)

Fatigue / Low energy: clinical rate of 6% at low dose. Feeling tired or having less energy than usual, especially in the first weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportpancreatitis1%severe

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Pancreatitis (rare): 1%. Very rarely reported by users, but when it occurs it is described as extremely painful. Anyone who experienced it says: 'you will know immediately something is very wrong.'

Collected: 4/6/2026Extraction: medium
User reportpancreatitis1%severe

Patient advocacy forums reporting (2024-2026)

Pancreatitis (rare): clinical rate of 1% at high dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportpancreatitis1%severe

Patient advocacy forums reporting (2024-2026)

Pancreatitis (rare): clinical rate of 1% at medium dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportpancreatitis1%severe

Patient advocacy forums reporting (2024-2026)

Pancreatitis (rare): clinical rate of 1% at low dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: lown=200Extraction: high
News sourcepancreatitis1%severe

FDA adverse event reports (2024-2025)

Pancreatitis (rare): clinical rate of 1% at high dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourcepancreatitis1%severe

FDA adverse event reports (2024-2025)

Pancreatitis (rare): clinical rate of 1% at medium dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourcepancreatitis1%severe

FDA adverse event reports (2024-2025)

Pancreatitis (rare): clinical rate of 1% at low dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studypancreatitis1%severe

Washington University comprehensive study (2025)

Pancreatitis (rare): clinical rate of 1% at high dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studypancreatitis1%severe

Washington University comprehensive study (2025)

Pancreatitis (rare): clinical rate of 1% at medium dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studypancreatitis1%severe

Washington University comprehensive study (2025)

Pancreatitis (rare): clinical rate of 1% at low dose. Inflammation of the pancreas. RARE but SERIOUS. Symptoms: severe stomach pain radiating to the back, nausea, vomiting. Stop treatment immediately and seek medical help.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportheadache18%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Headache: 18%. Generally mild and short-lived. Users report it's most common in the first week and during dose increases.

Collected: 4/6/2026Extraction: medium
News sourceheadache14%mild

AAMC GLP-1 overview (2025)

Headache: clinical rate of 14% at high dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourceheadache12%mild

AAMC GLP-1 overview (2025)

Headache: clinical rate of 12% at medium dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourceheadache8%mild

AAMC GLP-1 overview (2025)

Headache: clinical rate of 8% at low dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportheadache14%mild

Weight loss medication user forums (2024-2026)

Headache: clinical rate of 14% at high dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportheadache12%mild

Weight loss medication user forums (2024-2026)

Headache: clinical rate of 12% at medium dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportheadache8%mild

Weight loss medication user forums (2024-2026)

Headache: clinical rate of 8% at low dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studyheadache14%mild

SURMOUNT-5 Trial (NEJM 2025)

Headache: clinical rate of 14% at high dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studyheadache12%mild

SURMOUNT-5 Trial (NEJM 2025)

Headache: clinical rate of 12% at medium dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studyheadache8%mild

SURMOUNT-5 Trial (NEJM 2025)

Headache: clinical rate of 8% at low dose. Mild to moderate headaches, especially in the first 1-2 weeks.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportreduced_appetite55%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Reduced appetite: 55%. Users frequently describe this as 'food noise disappearing' — the constant thinking about food stops. Most view this as positive, not a side effect.

Collected: 4/6/2026Extraction: medium
News sourcereduced_appetite22%mild

NAM Understanding GLP-1 Drugs (2025)

Reduced appetite: clinical rate of 22% at high dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourcereduced_appetite15%mild

NAM Understanding GLP-1 Drugs (2025)

Reduced appetite: clinical rate of 15% at medium dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourcereduced_appetite8%mild

NAM Understanding GLP-1 Drugs (2025)

Reduced appetite: clinical rate of 8% at low dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportreduced_appetite22%mild

Reddit r/Mounjaro & r/Ozempic user experiences (2024-2026)

Reduced appetite: clinical rate of 22% at high dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportreduced_appetite15%mild

Reddit r/Mounjaro & r/Ozempic user experiences (2024-2026)

Reduced appetite: clinical rate of 15% at medium dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportreduced_appetite8%mild

Reddit r/Mounjaro & r/Ozempic user experiences (2024-2026)

Reduced appetite: clinical rate of 8% at low dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studyreduced_appetite22%mild

Long-term GLP-1 meta-analysis (PMC 2025)

Reduced appetite: clinical rate of 22% at high dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studyreduced_appetite15%mild

Long-term GLP-1 meta-analysis (PMC 2025)

Reduced appetite: clinical rate of 15% at medium dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studyreduced_appetite8%mild

Long-term GLP-1 meta-analysis (PMC 2025)

Reduced appetite: clinical rate of 8% at low dose. Significantly less hunger and interest in food. This is actually the intended effect — but can feel unsettling at first.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportconstipation22%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Constipation: 22%. Often underreported in studies. Forum users mention it more than clinical data suggests. Fibre supplements help most people.

Collected: 4/6/2026Extraction: medium
News sourceconstipation18%mild

PCOM Safety review (2025)

Constipation: clinical rate of 18% at high dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourceconstipation12%mild

PCOM Safety review (2025)

Constipation: clinical rate of 12% at medium dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourceconstipation5%mild

PCOM Safety review (2025)

Constipation: clinical rate of 5% at low dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportconstipation18%mild

Viva Forum NL weight loss discussions (2025-2026)

Constipation: clinical rate of 18% at high dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportconstipation12%mild

Viva Forum NL weight loss discussions (2025-2026)

Constipation: clinical rate of 12% at medium dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportconstipation5%mild

Viva Forum NL weight loss discussions (2025-2026)

Constipation: clinical rate of 5% at low dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studyconstipation18%mild

Real-world evidence systematic review (PMC 2025)

Constipation: clinical rate of 18% at high dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studyconstipation12%mild

Real-world evidence systematic review (PMC 2025)

Constipation: clinical rate of 12% at medium dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studyconstipation5%mild

Real-world evidence systematic review (PMC 2025)

Constipation: clinical rate of 5% at low dose. Difficulty passing stools or less frequent bowel movements. Caused by slowed stomach emptying.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportdiarrhea30%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Diarrhoea: 30%. Users report it varies widely — some experience it daily for 1-2 weeks, others barely notice. Severity seems dose-dependent.

Collected: 4/6/2026Extraction: medium
News sourcediarrhea25%mild

Washington University side effects study (2025)

Diarrhoea: clinical rate of 25% at high dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourcediarrhea18%mild

Washington University side effects study (2025)

Diarrhoea: clinical rate of 18% at medium dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourcediarrhea10%mild

Washington University side effects study (2025)

Diarrhoea: clinical rate of 10% at low dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportdiarrhea25%mild

Trustpilot reviews of weight management services (2025-2026)

Diarrhoea: clinical rate of 25% at high dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportdiarrhea18%mild

Trustpilot reviews of weight management services (2025-2026)

Diarrhoea: clinical rate of 18% at medium dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportdiarrhea10%mild

Trustpilot reviews of weight management services (2025-2026)

Diarrhoea: clinical rate of 10% at low dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studydiarrhea25%mild

SURMOUNT-5 Trial (NEJM 2025)

Diarrhoea: clinical rate of 25% at high dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studydiarrhea18%mild

SURMOUNT-5 Trial (NEJM 2025)

Diarrhoea: clinical rate of 18% at medium dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studydiarrhea10%mild

SURMOUNT-5 Trial (NEJM 2025)

Diarrhoea: clinical rate of 10% at low dose. Loose or watery stools, sometimes with urgency. Second most common GI side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportnausea45%mild

Aggregated user reports (Reddit, forums, reviews)

User-reported rate for Nausea: 45%. Most users describe it as 'manageable' — like mild car sickness. Usually worst in week 1-2, then fades.

Collected: 4/6/2026Extraction: medium
News sourcenausea40%mild

RAND Corporation side effects study (2025)

Nausea: clinical rate of 40% at high dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
News sourcenausea28%mild

RAND Corporation side effects study (2025)

Nausea: clinical rate of 28% at medium dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
News sourcenausea15%mild

RAND Corporation side effects study (2025)

Nausea: clinical rate of 15% at low dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high
User reportnausea40%mild

Reddit r/loseit & r/Mounjaro user reports (2024-2026)

Nausea: clinical rate of 40% at high dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
User reportnausea28%mild

Reddit r/loseit & r/Mounjaro user reports (2024-2026)

Nausea: clinical rate of 28% at medium dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
User reportnausea15%mild

Reddit r/loseit & r/Mounjaro user reports (2024-2026)

Nausea: clinical rate of 15% at low dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high
Clinical studynausea40%mild

SURMOUNT-5 Trial (NEJM 2025)

Nausea: clinical rate of 40% at high dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: highn=300Extraction: high
Clinical studynausea28%mild

SURMOUNT-5 Trial (NEJM 2025)

Nausea: clinical rate of 28% at medium dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: mediumn=500Extraction: high
Clinical studynausea15%mild

SURMOUNT-5 Trial (NEJM 2025)

Nausea: clinical rate of 15% at low dose. Feeling sick to your stomach, sometimes with the urge to vomit. The most commonly reported side effect.

Collected: 4/6/2026Dose: lown=200Extraction: high

Last updated: 5/1/2026. This database is updated daily with new sources.

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