An independent GLP-1 safety database. Real data from clinical trials, patient experiences, and regulatory reports — free, with every source cited.
2,969
Data points
15
Effects tracked
9
Drugs covered
8
Data sources
See your personalised risk profile for 15 side effects
Try itPredict your weight loss journey from STEP, SURMOUNT and SCALE trial data
Try itAssess your risk of muscle loss and get evidence-based recommendations
Try itUnderstand what happens when you stop — and how to prepare
Try itOur Companies House audit: 98 brand-new shell companies, no credible GLP-1 supplier, and documented harm.
Read moreIndia's patent expiry opens the door for dozens of affordable generic versions.
Read moreRegistered generics make weight management accessible to millions.
Read more
012,969 structured data points across 15 side effects and 9 medications — updated daily, sources cited.
02The free predictor estimates your side-effect risks and weight trajectory from your profile.
03Clinical trials side by side with real-world reports, plus weekly market and pricing analysis by country.
04Missing a side effect, drug, or data source? Your suggestions steer what we collect next.
Almost everything written about GLP-1 online comes from someone selling you something — the manufacturer, a clinic, or the grey market. We don't sell medication. We publish the data.
We don't prescribe, don't dispense, and earn nothing from your treatment — so our numbers have nothing to sell. Every data point carries its source: clinical trials, FDA FAERS, regulators, and patient reports. Methodology published in full.
Read the methodologyAn independent, fully cited GLP-1 safety and efficacy database — drawn from clinical trials, FDA FAERS, regulatory reports, and patient experiences. Personalised forecasts for weight loss, side effects, and muscle preservation, to take to your own doctor.
See your forecastWeekly-updated tracking of GLP-1 supply, demand, and pricing across major global markets — patent expiries, licensed generic launches, cross-market pricing, and what you can check yourself about a pack and its cold chain.
Explore the marketThe trials behind our pooled rates tracked adverse events for anywhere from 1.7 to 364 weeks — 12 days to 7 years. As of 3 October 2026, 755 of the 1,671 eligible registry rows that state a counting window (45.2%) come from trials of 26 weeks or less, yet across seven tracked effects those short trials carry 1.1–2.4% of the pooled weight, not their row-count share. Nausea's own median stated rate is 8.0% in trials of 26 weeks or less and 25.2% in trials over two years — computed by the same windowMix function that runs on magistra.health, and checked against the live data store.
ReadSURPASS-2 (NCT03987919) randomized 1,879 adults with type 2 diabetes on metformin to tirzepatide 5, 10 or 15 mg or semaglutide 1 mg, open-label, for up to 44 weeks. Across six tracked side effects and three tirzepatide doses — 18 comparisons — the largest gaps were diarrhoea at 10 mg (+4.9 points, z=2.17) and reduced appetite at 15 mg (+3.6 points, z=2.15), both past the single-test line and short of the Bonferroni-corrected bar. No gap is established; two are suggestive. Every row read from the registry.
ReadACHIEVE-3 (NCT06045221) randomized 1,698 adults with type 2 diabetes on metformin between two daily GLP-1 tablets, orforglipron and oral semaglutide, at two dose levels for 52 weeks. At the low pair (12 vs 7 mg) orforglipron reported more nausea (26.4% vs 13.1%), vomiting (17.0% vs 7.7%) and diarrhoea (21.7% vs 13.1%), all three clearing a 16-test correction; at the high pair (36 vs 14 mg) no gap cleared it. Open-label and Lilly-funded. Every row read from the registry.
ReadAccess the GLP-1 Safety Database via our public API. Free for citations, subscription for bulk access.
curl magistra.health/api/data?q=overview{
"totalDataPoints": 2,969,
"totalEffectsTracked": 15,
"drugsTracked": ["semaglutide", "tirzepatide", "liraglutide", ...],
"dataSources": [{ "source": "PubMed", "points": ... }, ...]
}Magistra is a data source, not a clinic. Everything below is available right now, free and without an account.
Side-effect risk, weight trajectory, muscle loss, and discontinuation outlook, fitted to your characteristics.
2,969 data points, each carrying its source, with clinical and real-world rates kept separate.
Free public API, citable dataset, and published methodology for researchers, analysts, and journalists.
The database grows daily. Leave your email and we'll write when a major dataset release or new finding lands. No medication sales.
See your personal GLP-1 side-effect risk